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Pharmacology Quiz: Parasympathomimetics & Signal Transduction

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Pharmacology Quiz: Parasympathomimetics & Signal Transduction

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Questions and Answers

What is the effect of M2 and M4 receptors on adenyl cyclase?

Activation of phospholipase C

Opening of Ca2+ channels

Stimulation of adenyl cyclase

Inhibition of adenyl cyclase (correct)

What is the main mechanism of action of indirect acting parasympathomimetics?

Stimulation of phospholipase C

Inhibition of adenyl cyclase

Direct binding to muscarinic receptors

Inhibition of cholinesterase enzyme (correct)

Which of the following is an example of a reversible cholinesterase inhibitor?

Carbachol

Physostigmine (correct)

Organophosphorus compounds

Pilocarpine

What is the effect of M1, M3, and M5 receptors on phospholipase C?

Stimulation of phospholipase C Signup and view all the answers

What type of compounds are all choline esters?

Quaternary compounds Signup and view all the answers

Which of the following is an example of a direct acting parasympathomimetic?

Methacholine Signup and view all the answers

What is the effect of ACh on the atrium?

Decrease in contractility Signup and view all the answers

What is the effect of ACh on vascular smooth muscles?

Relaxation Signup and view all the answers

What is the effect of ACh on the urinary tract?

Contraction of the bladder and relaxation of the ureter Signup and view all the answers

What is the effect of ACh on exocrine glands?

Marked increase in glandular secretions Signup and view all the answers

What is the effect of ACh on the autonomic ganglia?

Activates both sympathetic and parasympathetic ganglia Signup and view all the answers

What is the therapeutic use of bethanechol?

Treatment of urinary retention Signup and view all the answers