Pharmacology Quiz: Parasympathomimetics & Signal Transduction
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Questions and Answers

What is the effect of M2 and M4 receptors on adenyl cyclase?

  • Activation of phospholipase C
  • Opening of Ca2+ channels
  • Stimulation of adenyl cyclase
  • Inhibition of adenyl cyclase (correct)

What is the main mechanism of action of indirect acting parasympathomimetics?

  • Stimulation of phospholipase C
  • Inhibition of adenyl cyclase
  • Direct binding to muscarinic receptors
  • Inhibition of cholinesterase enzyme (correct)

Which of the following is an example of a reversible cholinesterase inhibitor?

  • Carbachol
  • Physostigmine (correct)
  • Organophosphorus compounds
  • Pilocarpine

What is the effect of M1, M3, and M5 receptors on phospholipase C?

<p>Stimulation of phospholipase C (A)</p> Signup and view all the answers

What type of compounds are all choline esters?

<p>Quaternary compounds (D)</p> Signup and view all the answers

Which of the following is an example of a direct acting parasympathomimetic?

<p>Methacholine (C)</p> Signup and view all the answers

What is the effect of ACh on the atrium?

<p>Decrease in contractility (D)</p> Signup and view all the answers

What is the effect of ACh on vascular smooth muscles?

<p>Relaxation (B)</p> Signup and view all the answers

What is the effect of ACh on the urinary tract?

<p>Contraction of the bladder and relaxation of the ureter (B)</p> Signup and view all the answers

What is the effect of ACh on exocrine glands?

<p>Marked increase in glandular secretions (A)</p> Signup and view all the answers

What is the effect of ACh on the autonomic ganglia?

<p>Activates both sympathetic and parasympathetic ganglia (B)</p> Signup and view all the answers

What is the therapeutic use of bethanechol?

<p>Treatment of urinary retention (C)</p> Signup and view all the answers

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