12 Questions
What is the effect of M2 and M4 receptors on adenyl cyclase?
Inhibition of adenyl cyclase
What is the main mechanism of action of indirect acting parasympathomimetics?
Inhibition of cholinesterase enzyme
Which of the following is an example of a reversible cholinesterase inhibitor?
Physostigmine
What is the effect of M1, M3, and M5 receptors on phospholipase C?
Stimulation of phospholipase C
What type of compounds are all choline esters?
Quaternary compounds
Which of the following is an example of a direct acting parasympathomimetic?
Methacholine
What is the effect of ACh on the atrium?
Decrease in contractility
What is the effect of ACh on vascular smooth muscles?
Relaxation
What is the effect of ACh on the urinary tract?
Contraction of the bladder and relaxation of the ureter
What is the effect of ACh on exocrine glands?
Marked increase in glandular secretions
What is the effect of ACh on the autonomic ganglia?
Activates both sympathetic and parasympathetic ganglia
What is the therapeutic use of bethanechol?
Treatment of urinary retention
This quiz tests your knowledge of parasympathomimetics, their classifications, and the signal transduction pathways involved. Questions cover the mechanisms of M1, M2, M3, and M4 receptors and their effects on second messengers.
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