16 Questions
Who first discovered the genetic role of DNA?
Frederick Griffith
What did Frederick Griffith call the phenomenon whereby some living cells became pathogenic when mixed with heat-killed remains of a pathogenic strain?
Transformation
Who conducted research showing that genes are located on chromosomes, leading to DNA and protein becoming candidates for the genetic material?
T. H. Morgan
What were the two components of chromosomes that became candidates for the genetic material?
DNA and protein
When did the identification of the molecules of inheritance pose a major challenge to biologists?
Early in the 20th century
What did T. H. Morgan's group show about genes?
They are located on chromosomes
What provided more evidence for DNA as the genetic material?
Studies of viruses that infect bacteria
What technique did Maurice Wilkins and Rosalind Franklin use to study molecular structure?
X-ray crystallography
Who showed that DNA is the genetic material of a phage known as T2?
Alfred Hershey and Martha Chase
What did Erwin Chargaff report in 1950?
The base composition of DNA varies from one species to the next
What did Oswald Avery, Maclyn McCarty, and Colin MacLeod identify as the transforming substance?
DNA
What allowed James Watson to deduce that DNA was helical?
X-ray crystallographic images of DNA
According to Chargaff's rules, what is the relationship between the number of A and T bases and the number of G and C bases in any species?
$A = T$ and $G = C$
What did Alfred Hershey and Martha Chase conclude based on their experiment with the T2 phage?
$DNA$ provides the genetic information
Who used X-ray crystallography to study molecular structure?
Rosalind Franklin
What did Franklin's X-ray crystallographic images of DNA suggest about its structure?
It is made up of two strands forming a double helix
Test your understanding of the concept 16.1: DNA is the genetic material and the search for the genetic material in the context of nucleic acids and inheritance. This quiz is based on lecture presentations by Nicole Tunbridge and Kathleen Fitzpatrick.
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