5 Questions
What is a major obstacle in anti-viral drug discovery compared to antibacterial drug discovery?
Limitation of standardized in vitro cellular systems and in vivo animal models for studying viruses
Why is developing highly specific, effective, and safe antiviral drugs a complex process?
Viruses have a great ability to develop high rates of resistance to most antiviral drugs
What is a significant limitation of the majority of available antiviral drugs?
They inhibit only active replicating viruses, but do not eliminate non-replicating or latent viruses
Why does the development of highly specific, effective, and safe antiviral drugs still require extensive efforts and technical support?
Viruses are intracellular microorganisms which depend on the host cellular machinery for replication
Why are standardized in-vitro susceptibility tests and standardized antiviral drug-sensitivity tests currently unavailable?
There is no standardized in vitro cellular systems and in vivo animal models for studying viruses
Explore the obstacles and difficulties encountered in the discovery, development, and evolution of anti-viral drug therapy for a range of highly pathogenic viruses. From HCV and HBV to HIV, SARS, and COVID-19, understand the challenges faced in combating these viral diseases.
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