35 Questions
What is the mechanism of action of natamycin in treating corneal fungal infections?
Binding irreversibly to ergosterol in the cell membrane
Which antifungal drug is specifically mentioned as the only topical drug for fungal infections?
Nystatin
What is the main adverse effect associated with the use of natamycin in eye infections?
Hyperemia
Which antifungal medication is a derivative of fluconazole?
Voriconazole
What is the broad-spectrum microbicide mentioned in the text with poorly understood antimicrobial mechanisms?
Tea Tree Oil
What is the mechanism of action of guanosine analog in treating viral infections?
Affects viral enzymes (DNA polymerase)
Which antiviral medication has a prodrug that is rapidly absorbed in the gastrointestinal tract and converted to penciclovir?
Famciclovir
What is the off-label use of acyclovir in bell palsy treatment?
500mg TID x 7 days
What adverse effect is commonly associated with antiviral eye treatments?
Blurred vision
Which antiviral drug is known for causing corneal defects as an adverse effect?
Idoxuridine
What dosage regimen is recommended for the treatment of HSV keratitis with Ganciclovir?
500mg TID
Which antiviral medication has the highest bioavailability as a prodrug of acyclovir?
Valacyclovir
What is the main action of trifluridine (Viroptic) in treating viral infections?
Competitively inhibits viral DNA polymerase
What is the appropriate dosage for Bell's Palsy treatment with Valacyclovir?
1g TID x 7 days
Which antiviral drug should be used with caution in patients with renal impairment and dehydration?
Ganciclovir
Which antiviral medication works as a prodrug rapidly absorbed in the gastrointestinal tract and converted to penciclovir?
Famciclovir
What is the main adverse effect associated with the use of trifluridine (Viroptic) in treating viral infections?
Corneal defects
Which antiviral drug should be used cautiously in patients with renal impairment and dehydration?
Valganciclovir
What is the broad-spectrum microbicide mentioned in the text with poorly understood antimicrobial mechanisms?
Tea Tree Oil
Which antiviral medication has the highest bioavailability as a prodrug of acyclovir?
Valacyclovir
What dosage regimen is recommended for the treatment of Bell's Palsy with Valacyclovir?
QID x 10 days
Which antiviral medication causes corneal defects as an adverse effect during treatment?
Trifluridine
What is the main action of acyclovir in treating viral infections?
Inhibits viral DNA polymerase
What is the off-label use of valacyclovir mentioned in the text?
Fungal keratitis treatment
Which antiviral medication is known for causing neurotoxicity as an adverse effect?
Trifluridine
Which antiviral medication has a differentiating mechanism of action due to an added hydroxymethyl group compared to Acyclovir?
Famciclovir
Which antiviral drug should be used with caution in patients with bone marrow depression and hypoplasia?
Zidovudine
What is the appropriate dosage regimen for Valacyclovir in treating Bell's Palsy within 72 hours of symptom onset?
500mg TID x 7 days
Which antiviral medication is known for causing nausea, vomiting, diarrhea, and headache as adverse effects?
Famciclovir
In HSV keratitis prophylaxis, what is the dosage recommendation for Acyclovir?
250mg TID
Which antiviral eye treatment is specifically mentioned as being discontinued?
Idoxuridine
What is the primary distinguishing factor for Vidarabine (Vira-A) among other antiviral medications mentioned?
Low toxicity profile
'Thymidine analogs' are primarily known to inhibit which enzyme to prevent DNA synthesis in virus-infected and normal host cells?
Thymidine synthetase
What distinguishes Guanosine analogs in terms of their effect on viral DNA replication?
(Termination of viral DNA chain growth)
'Bell Palsy' treatment with which antiviral medication involves the additional use of steroids for new onset cases within 72 hours?
(Valtrex) Valacyclovir
Test your knowledge of anti-viral drugs such as Vidarabine, Idoxuridine, and their pharmacology, usage, dosage, adverse effects, and miscellaneous information. Learn about their mechanisms of action and implications for HSV cornea treatment.
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