Anti-Infective (Anti-Viral) Drugs Pharmacology Quiz
35 Questions
2 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the mechanism of action of natamycin in treating corneal fungal infections?

  • Binding irreversibly to ergosterol in the cell membrane (correct)
  • Inhibiting DNA replication of fungi
  • Activating antifungal enzymes within the fungal cells
  • Altering the fungal cell membrane composition

Which antifungal drug is specifically mentioned as the only topical drug for fungal infections?

  • Amphotericin B
  • Nystatin (correct)
  • Voriconazole
  • Fluconazole

What is the main adverse effect associated with the use of natamycin in eye infections?

  • Hyperemia (correct)
  • Nausea and vomiting
  • Hypokalemia
  • Chills and fever

Which antifungal medication is a derivative of fluconazole?

<p>Voriconazole (D)</p> Signup and view all the answers

What is the broad-spectrum microbicide mentioned in the text with poorly understood antimicrobial mechanisms?

<p>Tea Tree Oil (B)</p> Signup and view all the answers

What is the mechanism of action of guanosine analog in treating viral infections?

<p>Affects viral enzymes (DNA polymerase) (C)</p> Signup and view all the answers

Which antiviral medication has a prodrug that is rapidly absorbed in the gastrointestinal tract and converted to penciclovir?

<p>Famciclovir (B)</p> Signup and view all the answers

What is the off-label use of acyclovir in bell palsy treatment?

<p>500mg TID x 7 days (B)</p> Signup and view all the answers

What adverse effect is commonly associated with antiviral eye treatments?

<p>Blurred vision (D)</p> Signup and view all the answers

Which antiviral drug is known for causing corneal defects as an adverse effect?

<p>Idoxuridine (C)</p> Signup and view all the answers

What dosage regimen is recommended for the treatment of HSV keratitis with Ganciclovir?

<p>500mg TID (B)</p> Signup and view all the answers

Which antiviral medication has the highest bioavailability as a prodrug of acyclovir?

<p>Valacyclovir (D)</p> Signup and view all the answers

What is the main action of trifluridine (Viroptic) in treating viral infections?

<p>Competitively inhibits viral DNA polymerase (C)</p> Signup and view all the answers

What is the appropriate dosage for Bell's Palsy treatment with Valacyclovir?

<p>1g TID x 7 days (B)</p> Signup and view all the answers

Which antiviral drug should be used with caution in patients with renal impairment and dehydration?

<p>Ganciclovir (C)</p> Signup and view all the answers

Which antiviral medication works as a prodrug rapidly absorbed in the gastrointestinal tract and converted to penciclovir?

<p>Famciclovir (D)</p> Signup and view all the answers

What is the main adverse effect associated with the use of trifluridine (Viroptic) in treating viral infections?

<p>Corneal defects (B)</p> Signup and view all the answers

Which antiviral drug should be used cautiously in patients with renal impairment and dehydration?

<p>Valganciclovir (C)</p> Signup and view all the answers

What is the broad-spectrum microbicide mentioned in the text with poorly understood antimicrobial mechanisms?

<p>Tea Tree Oil (A)</p> Signup and view all the answers

Which antiviral medication has the highest bioavailability as a prodrug of acyclovir?

<p>Valacyclovir (B)</p> Signup and view all the answers

What dosage regimen is recommended for the treatment of Bell's Palsy with Valacyclovir?

<p>QID x 10 days (B)</p> Signup and view all the answers

Which antiviral medication causes corneal defects as an adverse effect during treatment?

<p>Trifluridine (C)</p> Signup and view all the answers

What is the main action of acyclovir in treating viral infections?

<p>Inhibits viral DNA polymerase (D)</p> Signup and view all the answers

What is the off-label use of valacyclovir mentioned in the text?

<p>Fungal keratitis treatment (D)</p> Signup and view all the answers

Which antiviral medication is known for causing neurotoxicity as an adverse effect?

<p>Trifluridine (C)</p> Signup and view all the answers

Which antiviral medication has a differentiating mechanism of action due to an added hydroxymethyl group compared to Acyclovir?

<p>Famciclovir (D)</p> Signup and view all the answers

Which antiviral drug should be used with caution in patients with bone marrow depression and hypoplasia?

<p>Zidovudine (A)</p> Signup and view all the answers

What is the appropriate dosage regimen for Valacyclovir in treating Bell's Palsy within 72 hours of symptom onset?

<p>500mg TID x 7 days (B)</p> Signup and view all the answers

Which antiviral medication is known for causing nausea, vomiting, diarrhea, and headache as adverse effects?

<p>Famciclovir (D)</p> Signup and view all the answers

In HSV keratitis prophylaxis, what is the dosage recommendation for Acyclovir?

<p>250mg TID (B)</p> Signup and view all the answers

Which antiviral eye treatment is specifically mentioned as being discontinued?

<p>Idoxuridine (A)</p> Signup and view all the answers

What is the primary distinguishing factor for Vidarabine (Vira-A) among other antiviral medications mentioned?

<p>Low toxicity profile (B)</p> Signup and view all the answers

'Thymidine analogs' are primarily known to inhibit which enzyme to prevent DNA synthesis in virus-infected and normal host cells?

<p>Thymidine synthetase (C)</p> Signup and view all the answers

What distinguishes Guanosine analogs in terms of their effect on viral DNA replication?

<p>(Termination of viral DNA chain growth) (B)</p> Signup and view all the answers

'Bell Palsy' treatment with which antiviral medication involves the additional use of steroids for new onset cases within 72 hours?

<p>(Valtrex) Valacyclovir (A)</p> Signup and view all the answers

More Like This

Mastering Anti-Infective Medications
10 questions
Pharmacology Midterm: Anti-infective Agents
0 questions
Antibiotic & Anti-Infective Drugs Overview
54 questions
Use Quizgecko on...
Browser
Browser