Podcast
Questions and Answers
Which component of a DNA virus is targeted by antivirals to stop DNA replication?
Which component of a DNA virus is targeted by antivirals to stop DNA replication?
- Capsid
- Genetic material (correct)
- Nucleus
- Envelope glycoproteins
In the context of viruses, what is the function of nucleotides?
In the context of viruses, what is the function of nucleotides?
- Promote viral fusion
- Structural unit for glycoproteins
- Storage of genetic information (correct)
- Act as antimicrobial agents
Which type of virus has a structure where glycoproteins are embedded with short spikes in the envelope?
Which type of virus has a structure where glycoproteins are embedded with short spikes in the envelope?
- RNA virus
- Retrovirus
- DNA virus (correct)
- Hepatitis virus
What is the primary role of antifungals in combating infections?
What is the primary role of antifungals in combating infections?
Which nucleotide base is found in both DNA and RNA?
Which nucleotide base is found in both DNA and RNA?
What is the specific viral enzyme required for the first phosphorylation in the viral life cycle described in the text?
What is the specific viral enzyme required for the first phosphorylation in the viral life cycle described in the text?
Which enzyme is responsible for converting RNA to DNA in the HIV retrovirus life cycle?
Which enzyme is responsible for converting RNA to DNA in the HIV retrovirus life cycle?
What is the name of the pathway used to incorporate thymidine into the growing viral genome?
What is the name of the pathway used to incorporate thymidine into the growing viral genome?
In the context of the viral life cycle described, what is the role of host enzymes?
In the context of the viral life cycle described, what is the role of host enzymes?
Which enzyme is essential for incorporating viral DNA into the growing genome after the triphosphate stage?
Which enzyme is essential for incorporating viral DNA into the growing genome after the triphosphate stage?
What is the main mechanism by which a virus attaches to a host cell?
What is the main mechanism by which a virus attaches to a host cell?
What is the role of viral thymidine kinase in the viral life cycle?
What is the role of viral thymidine kinase in the viral life cycle?
Which condition requires a greater decrease in immunity for its reactivation according to the text?
Which condition requires a greater decrease in immunity for its reactivation according to the text?
What factor can reactivate herpes zoster even with minimal sleep deprivation?
What factor can reactivate herpes zoster even with minimal sleep deprivation?
What process involves adding deoxyribonucleoside triphosphates to the growing DNA genome during viral replication?
What process involves adding deoxyribonucleoside triphosphates to the growing DNA genome during viral replication?
Which statement accurately describes viruses?
Which statement accurately describes viruses?
What is the main difference between viruses and bacteria?
What is the main difference between viruses and bacteria?
Which part of a virus consists of glycoproteins with spikes embedded in the envelope?
Which part of a virus consists of glycoproteins with spikes embedded in the envelope?
What type of nucleic acids can be found in viruses?
What type of nucleic acids can be found in viruses?
In the context of antiviral drugs, why is the mode of action different when compared to antibiotics?
In the context of antiviral drugs, why is the mode of action different when compared to antibiotics?
Which of the following is NOT a clinical use of Acyclovir?
Which of the following is NOT a clinical use of Acyclovir?
What is the primary target of Acyclovir in the treatment of viral infections?
What is the primary target of Acyclovir in the treatment of viral infections?
Which adverse reaction is most commonly associated with Acyclovir use?
Which adverse reaction is most commonly associated with Acyclovir use?
In which condition should Acyclovir be used with caution?
In which condition should Acyclovir be used with caution?
What is the prevalence of Acyclovir resistance in immunocompromised individuals?
What is the prevalence of Acyclovir resistance in immunocompromised individuals?
What is the role of thymidine kinase in the mechanism of action of nucleoside antivirals such as acyclovir and valacyclovir?
What is the role of thymidine kinase in the mechanism of action of nucleoside antivirals such as acyclovir and valacyclovir?
Which DNA viruses are effectively treated with nucleoside antivirals like famciclovir?
Which DNA viruses are effectively treated with nucleoside antivirals like famciclovir?
What happens when the immune system is unable to suppress Cytomegalovirus (CMV)?
What happens when the immune system is unable to suppress Cytomegalovirus (CMV)?
Which category of viruses are Herpes Simplex Virus 1 and 2 (HSV 1 and 2) classified under?
Which category of viruses are Herpes Simplex Virus 1 and 2 (HSV 1 and 2) classified under?
In the viral life cycle, what specific process is blocked by nucleoside antivirals like acyclovir and valacyclovir?
In the viral life cycle, what specific process is blocked by nucleoside antivirals like acyclovir and valacyclovir?
In the viral life cycle, which enzyme is responsible for incorporating nucleoside triphosphates into new viral genomes?
In the viral life cycle, which enzyme is responsible for incorporating nucleoside triphosphates into new viral genomes?
What is the role of acyclovir monophosphate in interrupting the replication of viral DNA?
What is the role of acyclovir monophosphate in interrupting the replication of viral DNA?
Which oral antiviral agent is commonly used for treating Herpes Zoster?
Which oral antiviral agent is commonly used for treating Herpes Zoster?
What is the mechanism of action of Valacyclovir in treating viral infections?
What is the mechanism of action of Valacyclovir in treating viral infections?
Which off-label use is associated with Acyclovir (Zovirax)?
Which off-label use is associated with Acyclovir (Zovirax)?
What role does viral DNA polymerase play in the viral life cycle?
What role does viral DNA polymerase play in the viral life cycle?
What is the primary target of antiviral medication like Acyclovir in the viral life cycle?
What is the primary target of antiviral medication like Acyclovir in the viral life cycle?
Which antiviral agent is commonly used for treating Herpes Simplex infections?
Which antiviral agent is commonly used for treating Herpes Simplex infections?
How do antivirals like Famciclovir exert their effects against viruses?
How do antivirals like Famciclovir exert their effects against viruses?
Which enzyme is responsible for phosphorylating nucleosides to create deoxyribonucleoside triphosphates in the viral life cycle?
Which enzyme is responsible for phosphorylating nucleosides to create deoxyribonucleoside triphosphates in the viral life cycle?
Flashcards
Viral DNA Polymerase Action
Viral DNA Polymerase Action
The process of adding deoxyribonucleoside triphosphates to the growing DNA genome during viral replication.
Viral Genetic Material
Viral Genetic Material
The component of a DNA virus targeted by antivirals to inhibit DNA replication.
Antifungal Function
Antifungal Function
The primary role of antifungals in combating infections.
Shared Nucleotide Base
Shared Nucleotide Base
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Viral Thymidine Kinase
Viral Thymidine Kinase
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Reverse Transcriptase
Reverse Transcriptase
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Salvage Pathway
Salvage Pathway
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Viral Attachment
Viral Attachment
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Viral Thymidine Kinase Role
Viral Thymidine Kinase Role
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Viruses vs. Bacteria
Viruses vs. Bacteria
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Viral Envelope
Viral Envelope
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Acyclovir Target
Acyclovir Target
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Acyclovir Side Effect
Acyclovir Side Effect
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Acyclovir Resistance Prevalence
Acyclovir Resistance Prevalence
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Nucleoside Antiviral Action
Nucleoside Antiviral Action
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Herpes Simplex Virus Category
Herpes Simplex Virus Category
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Nucleoside Antiviral Block
Nucleoside Antiviral Block
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Viral Thymidine Kinase
Viral Thymidine Kinase
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Acyclovir Monophosphate Role
Acyclovir Monophosphate Role
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Valacyclovir Action
Valacyclovir Action
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Viral DNA Polymerase Role
Viral DNA Polymerase Role
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Antiviral Target
Antiviral Target
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Herpes Simplex Treatment
Herpes Simplex Treatment
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Famciclovir Action
Famciclovir Action
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Nucleoside Phosphorylation
Nucleoside Phosphorylation
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CMV Infection Outcome
CMV Infection Outcome
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Herpes Zoster Treatment
Herpes Zoster Treatment
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Acyclovir Off-Label Use
Acyclovir Off-Label Use
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