Cervical Cancer Diagnosis and Management

What clinical feature is associated with invasive cervical cancer?

What is a characteristic feature of tumors causing a barrel cervix?

Which diagnostic technique involves identifying atypical cells?

What type of metastasis risk correlates with cervical cancer tumors of 3mm?

What indicates that cancer has extended into the parametrial soft tissues?

What color indicates maturity in squamous cells?

Which feature is characteristic of High-Grade Squamous Intraepithelial Lesions (HSIL)?

What does diffuse positivity with p16 indicate in cervical lesions?

Which of the following tests is essential for diagnosing HPV cervical infection?

What does dual-stain testing identify in Pap test samples?

Which statement about the HPV test is correct?

What marker is used to identify cell activity in cervical lesions?

What significance does koilocytotic atypia have in squamous cells?

Which characteristic is typical of a hydatidiform mole?

What is a key histopathological feature of a complete hydatidiform mole?

Which of the following types of hydatidiform moles is known to be compatible with embryogenesis?

What does the term 'invasive hydatidiform mole' refer to?

Which is NOT a feature observed in molar pregnancies?

In the evaluation of gestational trophoblastic disease, which diagnostic technique is often used?

Which of the following closely resembles the diagnostic features of a hydatidiform mole?

What is the primary reason for performing surgical curettage in cases of hydatidiform mole?

Co-testing for cervical cancer includes the identification of atypical cells.
Dual staining (p16 and Ki-67) is a novel approach using molecular stains to detect high-risk HPV.
p16 positivity serves as a surrogate marker for high-risk HPV presence.

Invasive cervical cancers present with unexpected vaginal bleeding, leukorrhea, painful coitus (dyspareunia), or dysuria.
Palpation reveals tumor encirclement of the cervix, leading to a barrel-shaped cervix and cervical diameter widening beyond 4 cm.
Tumors may invade parametrial soft tissues, leading to pelvic lymph node involvement and uterine fixation to surrounding structures.

The risk of metastasis to the bladder is significant; tumors greater than 3 mm have a 10% chance.
Features include a barrel-shaped cervix with heterogeneous invasion into the parametrium.

Spectrum of SIL includes:
- Low-grade SIL (LSIL) with koilocytotic atypia.
- High-grade SIL (HSIL) with progressive atypia in all epithelial layers.
- HSIL with diffuse atypia and loss of maturation, indicating carcinoma in situ.

Defined by voluminous, cystic swelling resembling grape-like structures.
Molar lesions categorized as:
- Complete Moles: Not compatible with embryogenesis; seldom contain fetal parts.
- Partial Moles: Compatible with embryogenesis; may contain fetal parts.
- Invasive Moles: Complete moles that invade uterine walls.

Increased trophoblast proliferation is noted in histopathological examination of hydatidiform moles.
Enlargement and avascularity of chorionic villi are significant findings, along with formation of cisterns.

Pap tests and HPV tests are utilized for cervical cancer screening.
HPV test amplifies viral DNA via PCR, while Pap smear detects cellular abnormalities.
Surgical curettage may be performed for histopathological examination to remove foreign contents.