Central Nervous System (CNS) Infections: Meningitis Focus
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Questions and Answers

What is considered the gold standard for the diagnosis of bacterial meningitis?

  • CSF protein level
  • MRI of the brain
  • CSF culture (correct)
  • Clinical signs and symptoms
  • What may cause the Gram stain and CSF culture to be negative in patients with bacterial meningitis?

  • Prior antibiotic therapy (correct)
  • MRI of the brain
  • Polymerase chain reaction (PCR) techniques
  • CSF protein level
  • What are the goals of bacterial meningitis treatment?

  • Increased inflammation
  • Antibiotic resistance
  • Eradication of infection, symptom amelioration, and mortality reduction (correct)
  • ICP monitoring
  • What should the time period be from suspected diagnosis to initiation of antibiotic treatment in bacterial meningitis?

    <p>1 hour (C)</p> Signup and view all the answers

    How can problems of antibiotic penetration into the meninges be overcome?

    <p>Direct instillation of antibiotics intrathecally or intraventricularly (D)</p> Signup and view all the answers

    What is the focus of the lecture mentioned in the text?

    <p>Meningitis (C)</p> Signup and view all the answers

    Which of the following is NOT mentioned as a common cause of bacterial meningitis?

    <p>Mycobacterium tuberculosis (B)</p> Signup and view all the answers

    What is the critical first step in acquiring acute bacterial meningitis according to the text?

    <p>Nasopharyngeal colonization by the bacterial pathogen (B)</p> Signup and view all the answers

    What is mentioned as a risk factor for bacterial meningitis in the text?

    <p>Active exposure to cigarette smoke (C)</p> Signup and view all the answers

    What leads to cerebral edema, decreased cerebral blood flow, and death in cases of meningitis according to the text?

    <p>Activation of host inflammatory pathways (A)</p> Signup and view all the answers

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