6 Questions
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit the cyclooxygenase (COX) enzyme, thereby preventing the synthesis of prostaglandins.
True
COX-1 is an inducible enzyme that is primarily responsible for the formation of prostaglandins during inflammation or injury.
False
Prostaglandins play a role in inducing pain, fever, and inflammation, as well as contracting the uterus during menstruation in non-pregnant women.
True
Opioid (narcotic) analgesics relieve pain by acting solely on the cortical regions of the brain and do not produce euphoria or addiction.
False
$\text{Arachidonic acid is released by the action of phospholipase A}_{2}$ on phospholipids, and it serves as a substrate for both the cyclooxygenase (COX) and lipoxygenase (LOX) enzymes.
True
COX-3, a newly discovered form of the cyclooxygenase enzyme, is primarily expressed in the brain and plays a central role in pain perception.
True
Test your knowledge on the classification of central analgesics based on their mode of action and effects. Learn about non-steroidal anti-inflammatory drugs and opioid analgesics used to relieve different types of pain.
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