10 Questions
What is the primary source of heme lost during degradation?
Erythrocytes
Which organ is responsible for the excretion of bilirubin diglucuronide into the bile?
Liver
What is the normal level of bilirubin in serum?
2-17 micromolar
What is the most common source of vitamin B9 (folate)?
Green leafy vegetables
What are the symptoms of a mild or borderline folate deficiency?
Loss of appetite and weight loss
Which enzyme uses B12 as a cofactor in the synthesis of methionine from homocysteine?
Methionine synthase
What is the role of 5,10-methylene THF in the body?
Act as a single methyl group donor
What hypothesis explains the similarity in signs and symptoms of B12 and folate deficiency?
5-Methyl-THF trap hypothesis
What is the function of formimino-glutamate (FIGLU) in the body?
Breakdown product of histidine
"Megaloblasts" are oversized RBC precursors found in which part of the body?
Bone marrow
Test your knowledge about the translocation and storage of iron in cells, including its incorporation into heme and iron-sulfur clusters, and its storage in the form of ferritin. Learn about the regulation of iron levels and the clinical measurement of ferritin for conditions such as anemia and hemochromatosis.
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