Podcast
Questions and Answers
Which molecule is the primary carrier of iron in the blood?
Which molecule is the primary carrier of iron in the blood?
- Ferrous sulfate
- Hemoglobin
- Ferritin
- Transferrin (correct)
What is the role of transferrin receptor 1 (TfR1) in iron uptake?
What is the role of transferrin receptor 1 (TfR1) in iron uptake?
- It facilitates receptor-mediated endocytosis (correct)
- It binds to iron(III)
- It reduces iron(III) to iron(II)
- It releases iron from transferrin
What happens to iron affinity for transferrin in the acidic environment of the endosome?
What happens to iron affinity for transferrin in the acidic environment of the endosome?
- It increases
- It remains the same
- It becomes toxic
- It decreases (correct)
How is iron transported into the cytosol from the endosome?
How is iron transported into the cytosol from the endosome?
What enzyme reduces iron(III) to iron(II) within the endosomal membrane?
What enzyme reduces iron(III) to iron(II) within the endosomal membrane?
Which molecule is responsible for binding the majority of iron in the blood?
Which molecule is responsible for binding the majority of iron in the blood?
What is the function of transferrin receptor 1 (TfR1) on the cell surface?
What is the function of transferrin receptor 1 (TfR1) on the cell surface?
What happens to the affinity of transferrin for iron in the acidic environment of the endosome?
What happens to the affinity of transferrin for iron in the acidic environment of the endosome?
Which enzyme reduces iron(III) to iron(II) within the endosomal membrane?
Which enzyme reduces iron(III) to iron(II) within the endosomal membrane?
How is iron transported into the cytosol from the endosome?
How is iron transported into the cytosol from the endosome?
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