Cell Migration and Actin in Cell Biology
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Questions and Answers

Which of the following is responsible for the breakdown of the nuclear envelope during mitosis?

  • Anaphase-promoting complex (APC/C)
  • S-Cdk
  • M-Cdk (correct)
  • G1/S-Cdk

What is the primary function of condensins in the cell cycle?

  • Initiating DNA replication
  • Reorganizing and compacting chromosomes (correct)
  • Holding sister chromatids together
  • Regulating transcription during G1 phase

Which of the following is a potential cause of uncontrolled cell division, a hallmark of cancer?

  • Inactivation of M-Cdk
  • Inactivation of G1/S-Cdk
  • Inactivation of p21
  • Inactivation of p53 (correct)

What is the primary function of the Origin Recognition Complex (ORC) in the cell cycle?

<p>Initiating DNA replication during S phase (C)</p> Signup and view all the answers

Which of the following is responsible for holding sister chromatids together during mitosis?

<p>Cohesins (D)</p> Signup and view all the answers

Which of the following statements about actin structures is correct?

<p>Actin polymerization drives the membrane forward. (C)</p> Signup and view all the answers

What is the primary function of focal adhesions?

<p>To adhere the cell to the surface and transmit signals. (B)</p> Signup and view all the answers

What is the primary function of the cohesin complex during the cell cycle?

<p>To keep sister chromatids together until anaphase (B)</p> Signup and view all the answers

Which of the following statements about intermediate filaments is incorrect?

<p>They are the thinnest cytoskeletal filaments. (B)</p> Signup and view all the answers

Which of the following is the primary mechanism by which apoptosis avoids triggering an inflammatory response?

<p>Apoptosis is a controlled and tidy process (A)</p> Signup and view all the answers

What is the primary function of cyclin-dependent kinases (CDKs) in the cell cycle?

<p>To initiate and regulate the progression through the cell cycle phases. (D)</p> Signup and view all the answers

How do oncogenes contribute to cancer development?

<p>Oncogenes disrupt the cell cycle and promote uncontrolled cell division (B)</p> Signup and view all the answers

Which of the following statements about cyclins is correct?

<p>Different cyclins are used in different phases of the cell cycle. (B)</p> Signup and view all the answers

Which of the following is a key role of tumor suppressor proteins in cancer prevention?

<p>Tumor suppressors negatively regulate cell cycle progression and cell growth (D)</p> Signup and view all the answers

Which phase of the cell cycle is most likely to be deregulated in cancer cells?

<p>The G1 phase. (D)</p> Signup and view all the answers

What is the primary function of the anaphase-promoting complex (APC/C) during the cell cycle?

<p>To trigger the separation of sister chromatids at anaphase (C)</p> Signup and view all the answers

What is the primary role of DNA damage repair mechanisms in preventing cancer development?

<p>DNA repair mechanisms prevent the accumulation of genetic alterations that can lead to uncontrolled cell growth (D)</p> Signup and view all the answers

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