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Cell Migration and Actin in Cell Biology

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Cell Migration and Actin in Cell Biology

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Questions and Answers

Which of the following is responsible for the breakdown of the nuclear envelope during mitosis?

Anaphase-promoting complex (APC/C)

S-Cdk

M-Cdk (correct)

G1/S-Cdk

What is the primary function of condensins in the cell cycle?

Initiating DNA replication

Reorganizing and compacting chromosomes (correct)

Holding sister chromatids together

Regulating transcription during G1 phase

Which of the following is a potential cause of uncontrolled cell division, a hallmark of cancer?

Inactivation of M-Cdk

Inactivation of G1/S-Cdk

Inactivation of p21

Inactivation of p53 (correct)

What is the primary function of the Origin Recognition Complex (ORC) in the cell cycle?

Initiating DNA replication during S phase Signup and view all the answers

Which of the following is responsible for holding sister chromatids together during mitosis?

Cohesins Signup and view all the answers

Which of the following statements about actin structures is correct?

Actin polymerization drives the membrane forward. Signup and view all the answers

What is the primary function of focal adhesions?

To adhere the cell to the surface and transmit signals. Signup and view all the answers

What is the primary function of the cohesin complex during the cell cycle?

To keep sister chromatids together until anaphase Signup and view all the answers

Which of the following statements about intermediate filaments is incorrect?

They are the thinnest cytoskeletal filaments. Signup and view all the answers

Which of the following is the primary mechanism by which apoptosis avoids triggering an inflammatory response?

Apoptosis is a controlled and tidy process Signup and view all the answers

What is the primary function of cyclin-dependent kinases (CDKs) in the cell cycle?

To initiate and regulate the progression through the cell cycle phases. Signup and view all the answers

How do oncogenes contribute to cancer development?

Oncogenes disrupt the cell cycle and promote uncontrolled cell division Signup and view all the answers

Which of the following statements about cyclins is correct?

Different cyclins are used in different phases of the cell cycle. Signup and view all the answers

Which of the following is a key role of tumor suppressor proteins in cancer prevention?

Tumor suppressors negatively regulate cell cycle progression and cell growth Signup and view all the answers

Which phase of the cell cycle is most likely to be deregulated in cancer cells?

The G1 phase. Signup and view all the answers

What is the primary function of the anaphase-promoting complex (APC/C) during the cell cycle?

To trigger the separation of sister chromatids at anaphase Signup and view all the answers

What is the primary role of DNA damage repair mechanisms in preventing cancer development?

DNA repair mechanisms prevent the accumulation of genetic alterations that can lead to uncontrolled cell growth Signup and view all the answers