Cell Cycle Quiz
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Questions and Answers

What is the longest part of the cell cycle?

  • G2 phase
  • Prophase
  • Interphase (correct)
  • Mitosis

Which cells in humans contain 46 chromosomes?

  • Egg and sperm cells
  • Somatic cells (correct)
  • All of the cells in the body (correct)
  • Cells in anaphase

Which characteristic would not be exhibited by cancer cells?

  • Density-dependent inhibition (correct)
  • Apoptosis
  • Metastasis
  • Passing through the restriction point

What typically occurs after a cell passes the restriction point in G1 phase?

<p>Undergo chromosome duplication (A)</p> Signup and view all the answers

What is the primary role of the mitotic spindle during cell division?

<p>To separate sister chromatids (A)</p> Signup and view all the answers

What is a karyotype?

<p>A pictorial display of an individual's chromosomes (D)</p> Signup and view all the answers

What are autosomes?

<p>The first 22 pairs of chromosomes (D)</p> Signup and view all the answers

What happens during telophase of mitosis?

<p>Nuclear membranes form around separated chromosomes (B)</p> Signup and view all the answers

At which phase of the cell cycle do centrioles begin to move apart and chromatin condenses into chromosomes?

<p>Prophase (B)</p> Signup and view all the answers

Why do specialized cells like neurons and muscle cells divide infrequently?

<p>They have entered the G0 phase of the cell cycle. (D)</p> Signup and view all the answers

What is cytokinesis?

<p>The division of the cytoplasm. (B)</p> Signup and view all the answers

Which phase of cell division involves alignment of chromosomes on the equator of the cell?

<p>Metaphase (B)</p> Signup and view all the answers

What is the role of the mitotic spindle during cell division?

<p>To separate sister chromatids. (D)</p> Signup and view all the answers

What explains the phenomenon where neighboring cells signal each other to stop dividing?

<p>Density-dependent inhibition (C)</p> Signup and view all the answers

Which statement is true regarding transformed (cancer) cells?

<p>They lose cell cycle control. (C)</p> Signup and view all the answers

What defines a genome?

<p>All the genetic material of an organism. (B)</p> Signup and view all the answers

What occurs during the first meiotic division?

<p>All of the above occur. (D)</p> Signup and view all the answers

Which statement is not true regarding homologous chromosomes?

<p>Crossing over occurs between sister chromatids. (A)</p> Signup and view all the answers

How do cancer cells differ from normal cells?

<p>Cancer cells continue to divide despite density-dependent inhibition. (B)</p> Signup and view all the answers

Which macromolecules are eukaryotic chromosomes primarily composed of?

<p>DNA and proteins (D)</p> Signup and view all the answers

What does not occur during mitosis?

<p>Synthesis of DNA (C)</p> Signup and view all the answers

In which phase do sister chromatids separate?

<p>Anaphase of mitosis (B), Anaphase II of meiosis (D)</p> Signup and view all the answers

What is a key difference between asexual and sexual reproduction?

<p>Asexual reproduction only uses mitosis. (B)</p> Signup and view all the answers

A human cell containing 22 autosomes and a Y chromosome is classified as what?

<p>A sperm (B)</p> Signup and view all the answers

If a heterozygous pea plant is crossed with a homozygous tall pea plant, what is the probability that the offspring will be dwarf in size?

<p>0 (C)</p> Signup and view all the answers

The frequency of Down syndrome in the human population is most closely correlated with which of the following?

<p>Age of the mother (B)</p> Signup and view all the answers

Why do the F1 offspring of Mendel's classic pea cross always look like one of the two parental varieties?

<p>One phenotype was completely dominant over another. (B)</p> Signup and view all the answers

Independent assortment of chromosomes results from which process?

<p>Meiosis I (A)</p> Signup and view all the answers

With the genotype BbHh, how many unique gametes can be produced?

<p>4 (D)</p> Signup and view all the answers

Which of the following describes a male's genetic makeup for the X chromosome?

<p>Hemizygous (C)</p> Signup and view all the answers

Which condition is the only viable monosomy known to occur in newborns?

<p>Turner syndrome (A)</p> Signup and view all the answers

How are closely linked genes inherited?

<p>They are inherited together due to their proximity on the same chromosome. (C)</p> Signup and view all the answers

Flashcards

Restriction point

A point in the G1 phase where a cell commits to division or proceeds to G0

Sister chromatids separate

During anaphase of mitosis, cohesion proteins break down, separating sister chromatids, allowing chromosomes to move to opposite poles.

Mitostic spindle begins to form

In prophase, the spindle apparatus starts to assemble, composed of microtubules that will play a key role in chromosome alignment and separation.

Cytokinesis

Division of the cytoplasm following mitosis - forming two separate daughter cells.

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Chromosome replication

Process of duplicating chromosomes occurring in the S phase of the cell cycle.

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Chromosome alignment

Chromosomes align at the metaphase plate (equatorial plane) during metaphase of mitosis/meiosis.

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Nuclear membrane reformation

Reformation of the nuclear membrane around separated chromosomes, marking the end of mitosis.

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Longest stage cell cycle

Interphase, consists of three substages (G1, S, G2), is the longest stage and is crucial as it precedes mitosis.

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Meiosis I

The first division in meiosis, where homologous chromosomes separate.

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Centriole movement

Centrioles begin to separate during prophase of mitosis

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Specialized cell division

Neurons and muscles cells frequently enter G0, a non-dividing state.

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Sister Chromatids Separation

Occurs during anaphase of mitosis and anaphase II of meiosis.

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Cytokinesis

Cytoplasm division following mitosis

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Homologous Chromosomes

Pair of chromosomes with the same gene sequence

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Cancer Cells and Division

Cancer cells often ignore density-dependent inhibition and continue to divide uncontrollably.

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S-Phase

DNA is copied during the S-phase of the cell cycle.

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Interphase

The phase of the cell cycle that includes G1, S, and G2.

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Eukaryotic Chromosomes

Composed of DNA and proteins (histones).

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Mitosis vs. Sexual Reproduction

Mitosis produces identical copies, DNA replication happens earlier, whereas reproduction involves meiosis and produces distinct offspring from two parents

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Sister Chromatids

Identical copies of a chromosome

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Meiosis II

The second division in meiosis, similar to mitosis, where sister chromatids separate.

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Density-dependent inhibition

Cells stop dividing when they touch each other.

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Genome

The complete set of genetic material in an organism.

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Asexual Reproduction

Reproduction that involves a single parent creating genetically identical offspring via mitosis.

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Down Syndrome Aneuploidy

A genetic condition caused by an extra copy of chromosome 21, resulting in developmental delays and physical characteristics.

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Mother's Age & Down Syndrome

The risk of a child having Down syndrome increases with the mother's age.

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Complete Dominance in Pea Plants

A characteristic where one allele masks the expression of another allele, resulting in a single phenotype.

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Mendel's Pea Cross F1 Offspring

Offspring from a cross between different pea plant varieties often only display one parent's trait, due to complete dominance.

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Independent Assortment

The random distribution of homologous chromosomes during meiosis, leading to genetic variation in offspring.

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Barr Body Purpose

Inactive X chromosome in females, regulating gene expression to prevent a double dose of X-chromosome genes, a common occurrence during development.

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Monohybrid Cross

A genetic cross involving only one trait, examining the inheritance of a specific characteristic.

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Sex-Linked Recessive Example

A genetic condition where the gene for the trait is located on a sex chromosome (typically X in humans), affecting mostly males.

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Study Notes

Fill in the Blank

  • A non-dividing state is a phase when a cell has not passed the restriction point
  • Sister chromatids separate and chromosomes move apart
  • Mitotic spindle forms
  • Cell plate forms or cleavage furrow pinches cells apart
  • Chromosomes replicate
  • Chromosomes line up at the equatorial plane
  • Nuclear membranes form around separated chromosomes
  • Chromosomes become visible
  • Kinetochore-microtubule interactions move chromosomes to the midline
  • Longest stage of the cell cycle, composed of three substages
  • Microtubules interact with kinetochore proteins at the centromere region

Multiple Choice

  • The longest part of the cell cycle is interphase
  • Humans have 46 chromosomes in somatic cells, and that number is found in somatic cells
  • Cancer cells do not exhibit density-dependent inhibition
  • A cell that passes the restriction point in G1 will most likely undergo chromosome duplication
  • The restoration of the diploid chromosome number after halving in meiosis is due to fertilization

Additional Information

  • DNA replication
  • Somatic cell division is mitosis
  • A karyotype is a pictorial display of an individual's chromosomes
  • Autosomes are the first 22 pairs of chromosomes
  • During meiosis I: synapsis of homologous chromosomes occurs, the chromosome number becomes haploid, crossing over between nonsister chromatids occurs, paternal and maternal chromosomes assort randomly
  • Meiosis II is similar to mitosis because sister chromatids separate
  • Homologous chromosomes are not true for mitosis
  • The synapse during the S phase of meiosis
  • They travel together to the metaphase plate in prometaphase of meiosis I
  • Each parent contributes one set of homologous chromosomes to an offspring
  • Crossing over occurs between nonsister chromatids of homologous chromosomes as indicated by chiasmata
  • Cancer cells are always in the M phase of the cell cycle, suffering from density-dependence inhibition, and continue dividing even when densely packed together
  • Eukaryotic chromosomes are composed of DNA and proteins
  • A human cell containing 22 autosomes and a Y chromosome is a somatic cell of a male
  • Sister chromatids separate in anaphase of mitosis and anaphase II of meiosis
  • Asexual reproduction produces genetically identical offspring (mitosis)
  • Sexual reproduction involves two parents, producing genetically distinct offspring (meiosis)
  • Centrioles begin to move apart and chromatin condenses into chromosomes during prophase
  • Cytokinesis is the division of the cytoplasm
  • S-phase is when DNA is copied
  • G1, S, and G2 stages make up interphase
  • Bacteria cells use binary fission
  • Sister chromatids are identical
  • Chromosomes separate during anaphase
  • Human cells have 46 chromosomes, not 46 pairs
  • The microtubule-organizing center in animal cells is called centrosomes
  • Gametes are haploid
  • Crossing over occurs in meiosis I, but not meiosis II
  • A zygote is a cell right before fertilization
  • Meiosis starts with 1 cell and produces 4 cells
  • Mitosis starts with 1 cell and produces 2 genetically identical cells
  • The region where sister chromatids are most closely held together is called the centromere
  • Sister chromatids are held together by cohesins
  • The mitotic spindle plays a role in separating sister chromatids
  • Metaphase is characterized by alignment of chromosomes on the equator of the cell
  • Cells stop dividing when cell surface proteins contact neighboring cells through density-dependent inhibition
  • A genome is the complete set of an organism's genes
  • A syndrome is a group of traits typically found in conjunction with a particular chromosomal aberration or gene mutation
  • In pea plants, the tall phenotype is dominant to the dwarf phenotype
  • The frequency of Down syndrome in humans is most closely correlated with the age of the mother
  • F1 offspring of Mendel's pea cross always look like one of the parental varieties because each allele affects phenotypic expression independently
  • Phenotype is the observable characteristics of an organism

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Description

Test your knowledge on the phases of the cell cycle and key concepts such as interphase, mitosis, and chromosome behavior. This quiz includes fill-in-the-blank and multiple-choice questions that cover essential definitions and processes related to cell division and replication.

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