18 Questions
What is the primary cause of damage in reactions involving high LET radiations?
Direct ionization of atoms in molecules
What type of DNA damage is most likely to occur at low-dose exposures?
Single strand breaks
Which part of the cell is most sensitive to radiation?
Nucleus
What is the result of increased radiation exposure on the number of mutations?
The number of mutations increases
What is the likely outcome of double strand breaks that are too close to repair?
Mutations with adverse effects
What type of radiation is most likely to cause direct ionization of atoms in molecules?
High LET radiation
What is the most radiosensitive phase of the cell cycle?
G2-M phase
What is the relationship between cell division rate and radiosensitivity?
Radiosensitivity is directly proportional to cell division rate
Which type of cells are most at risk from radiation?
Actively dividing cells
What type of radiation damage occurs when ionization of atoms on key molecules takes place?
Direct action
What type of radiation is classified as indirectly ionizing?
Gamma and x-radiations
What is the effect of radiation on undifferentiated hematopoietic cells?
They are more sensitive to radiation and die easily
What is the consequence of DNA damage in germ cells?
Future offspring may be affected
What is the primary function of antioxidants in the cell?
To inhibit the oxidation of other molecules
What type of radiation is more likely to cause double-strand breaks in DNA?
High-LET radiation
What is the result of unrepairable DNA damage in somatic cells?
Cell death
What is the effect of increasing radiation exposure on the number of mutations?
It increases
What is the repair mechanism for single-strand breaks in DNA?
Using the undamaged strand as a template
Test your knowledge on the relationship between the cell cycle and radiosensitivity. Learn how the cell cycle phase affects a cell's sensitivity to radiation and how it's related to cell division and differentiation.
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