Cartilage and Bone Anatomy Quiz
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Questions and Answers

What type of tissue primarily makes up the bones?

Connective tissue.

Identify two functions of bones.

Support and protection.

What are 'sesamoid bones' and provide an example.

Bones that develop within tendons; the patella is an example.

What role do bones play in mineral storage?

<p>They store calcium and phosphate.</p> Signup and view all the answers

Explain the term 'pneumatized bones'.

<p>Hollow bones containing air pockets.</p> Signup and view all the answers

How do bones contribute to movement?

<p>By acting as a lever system for muscles.</p> Signup and view all the answers

What is the function of osteocalcin?

<p>It influences bone production, fat storage, and stimulates insulin production.</p> Signup and view all the answers

Define 'flat bones' and give two examples.

<p>Thin layers of compact bone surrounding spongy bone; examples include the skull and ribs.</p> Signup and view all the answers

What are irregular bones, and where are they typically found?

<p>Bones with varied shapes, found in the vertebrae and some facial bones.</p> Signup and view all the answers

What tissue types are present in bones, and why are they crucial?

<p>Connective, epithelial, and nervous tissue; they enable various bone functions.</p> Signup and view all the answers

What is the primary role of osteoclasts in bone formation?

<p>Osteoclasts break down bones by dissolving the calcified cartilage and allowing for new bone formation by osteoblasts.</p> Signup and view all the answers

Describe the process of endochondral ossification.

<p>Endochondral ossification involves the transformation of hyaline cartilage into bone, where chondrocytes proliferate, die, and are replaced by osteoblasts that form new bone.</p> Signup and view all the answers

What differentiates intramembranous ossification from endochondral ossification?

<p>Intramembranous ossification occurs directly within mesenchymal or connective tissue, while endochondral ossification involves a cartilage precursor.</p> Signup and view all the answers

Explain the significance of the epiphyseal plate in bone growth.

<p>The epiphyseal plate allows for the lengthening of bones during childhood and adolescence as chondrocytes proliferate and produce new cartilage.</p> Signup and view all the answers

What role do periosteal cells play in the growth of bone thickness?

<p>Periosteal cells differentiate into osteoblasts, producing bone matrix that results in bone thickness increase and formation of new ridges around blood vessels.</p> Signup and view all the answers

How do osteoblasts contribute to the formation of new bone tissue?

<p>Osteoblasts synthesize bone matrix and are responsible for mineralizing it, which leads to the formation of new bone.</p> Signup and view all the answers

What happens to chondrocytes during the process of calcification in bone growth?

<p>Chondrocytes enlarge and produce a calcified matrix before dying due to the lack of nutrients as the matrix becomes hardened.</p> Signup and view all the answers

What is the endosteum and its relevance to bone growth?

<p>The endosteum is a thin membrane lining the inner surface of the bone, formed from the periosteum during bone thickness growth, and is vital for new bone formation.</p> Signup and view all the answers

What are the three major types of cartilage and where is each typically found?

<p>The three major types of cartilage are hyaline cartilage found in joints, fibrocartilage that resists compression such as in intervertebral discs, and elastic cartilage which provides flexibility found in structures like the ear.</p> Signup and view all the answers

How do bones function as organs in the human body?

<p>Bones are considered organs because they are made up of multiple tissue types, including bone tissue, cartilage, blood vessels, and nerves, all working together to support and protect the body.</p> Signup and view all the answers

List the four classifications of bones by shape and provide an example for each.

<p>The classifications are long bones (e.g., femur), short bones (e.g., carpals), flat bones (e.g., skull), and irregular bones (e.g., vertebrae).</p> Signup and view all the answers

What are the main components of the extracellular matrix in bone tissue?

<p>The extracellular matrix in bone tissue consists primarily of collagen fibers and mineral deposits, primarily hydroxyapatite, which provide tensile strength and rigidity.</p> Signup and view all the answers

Differentiate between intramembranous and endochondral ossification.

<p>Intramembranous ossification occurs directly from mesenchymal tissue, forming flat bones like the skull, while endochondral ossification involves cartilage being replaced by bone, typical in long bones.</p> Signup and view all the answers

Describe the gross anatomy of a typical long bone.

<p>A typical long bone has a diaphysis (shaft), epiphyses (ends), and is comprised of both compact and spongy bone with a marrow cavity in the center.</p> Signup and view all the answers

What role do compression lines and tension lines play in bone structure?

<p>Compression lines are oriented to resist compressive forces, while tension lines are oriented to resist tensile forces, ensuring bones can withstand various loads.</p> Signup and view all the answers

Identify the two main divisions of the human skeleton and provide examples of bones from each.

<p>The two main divisions are the axial skeleton (e.g., skull, vertebrae) and the appendicular skeleton (e.g., femur, humerus).</p> Signup and view all the answers

What composes the perichondrium and what is its function in cartilage?

<p>The perichondrium is composed of an outer layer of fibroblasts and an inner layer of chondroblasts, serving as a supportive layer for cartilage and assisting in growth and repair.</p> Signup and view all the answers

How does fibrocartilage differ from hyaline cartilage in structure and function?

<p>Fibrocartilage contains large bundles of collagen for increased durability, enabling it to resist both compression and tension, while hyaline cartilage has a more homogeneous gel-like matrix suitable for smooth movement in joints.</p> Signup and view all the answers

What is the primary mineral component of the extracellular matrix in bone tissue?

<p>Hydroxyapatite.</p> Signup and view all the answers

How do osteoblasts contribute to bone formation?

<p>Osteoblasts secrete collagen fibers and initiate calcification.</p> Signup and view all the answers

Which type of bone cells are primarily involved in the resorption process?

<p>Osteoclasts.</p> Signup and view all the answers

What role does spongy bone play in the skeletal system?

<p>It reduces the weight of bones and supports red bone marrow.</p> Signup and view all the answers

Describe the structure of compact bone in terms of its organization.

<p>Compact bone is organized into osteons or Haversian systems.</p> Signup and view all the answers

What are the two layers of the periosteum?

<p>The outer fibrous layer and the inner cellular layer.</p> Signup and view all the answers

What is the primary function of osteocytes in bone tissue?

<p>Osteocytes maintain bone health and metabolism.</p> Signup and view all the answers

Explain the role of collagen fibers in the bone matrix.

<p>Collagen fibers provide elasticity and a framework for mineral crystal formation.</p> Signup and view all the answers

What distinguishes trabecular bone from cortical bone?

<p>Trabecular bone has no central canal and consists of trabeculae.</p> Signup and view all the answers

What types of cells are osteogenic cells and where are they found?

<p>Osteogenic cells are unspecialized bone cells found in the endosteum and periosteum.</p> Signup and view all the answers

What are the four primary functions of the periosteum?

<p>The periosteum isolates and protects the bone, provides a route for blood and nerve supply, participates in bone growth and repair, and attaches the bone to the connective tissue network.</p> Signup and view all the answers

How does the endosteum contribute to bone dynamics?

<p>The endosteum, a single layer of osteoprogenitor cells, plays an active role in bone growth and remodeling by covering trabeculae and the central canal of osteons.</p> Signup and view all the answers

Describe the blood supply to the diaphysis of a long bone.

<p>The diaphysis receives blood through a nutrient foramen which usually leads to a nutrient artery and nutrient vein.</p> Signup and view all the answers

What is the significance of the arrangement of compact and spongy bone concerning stress forces?

<p>Compact bone is thicker in areas subjected to greater forces, while spongy bone is organized to handle multidirectional tension, adapting to stress efficiently.</p> Signup and view all the answers

What role do surface markings on bones play in relation to tendons and ligaments?

<p>Surface markings provide anchor points for tendons and ligaments, adapting to the forces of tension and compression as muscles are used.</p> Signup and view all the answers

Study Notes

Cartilage

  • Connective tissue with collagen and/or elastic fibers in a gel-like structure.
  • Chondrocytes (cells) are located in lacunae (cavities).
  • Cartilage lacks nerves and blood vessels.
  • Some cartilage is surrounded by perichondrium, a connective tissue layer that supports the cartilage.

Types of Cartilage

  • Hyaline: Most common type; fine fibers in a gel-like matrix; found in most articulations (e.g., most joints).
  • Fibrocartilage: Large bundles of collagen; resists compression and tension forces (e.g., anulus fibrosus).
  • Elastic: Matrix of elastic fibers; provides flexibility (e.g., epiglottis).

Bones as Organs

  • Composed of connective tissue (bone, cartilage, adipose, blood), epithelial tissue, nervous tissue, and blood vessels.
  • Major functions of bones:
    • Support: Framework for the body, supporting weight and attachment for soft tissues.
    • Movement: Leverage system with muscles to produce movement.
    • Protection: Protects vital organs (e.g., skull, rib cage, vertebral column, pelvis).
    • Mineral Storage: Stores calcium and phosphate, which can be released into the bloodstream.
    • Blood Cell Production and Energy Storage: Red marrow produces red and white blood cells.
    • Energy Metabolism: Osteocalcin, a hormone produced by osteoblasts, influences bone production, fat storage, and stimulates insulin production.

Types of Bones

  • Flat bones: Thin layers of compact bone surrounding spongy bone (diploë). Examples: roof of skull, ribs, sternum, scapula.
  • Sutural bones: Oddly shaped bones inserted between flat bones of the skull. Structurally, these are flat bones.
  • Pneumatized bones: Hollow bones or containing air pockets. Example: ethmoid.
  • Long bones: Elongated shape. Examples: limbs, fingers, toes.
  • Short bones: Roughly cuboidal shape. Examples: carpals, tarsals.
  • Sesamoid bones: Present within tendons. Example: patella.
  • Irregular bones: Shape varies. Examples: vertebrae, some facial bones, heel bone.

Bone Formation

  • Endochondral Ossification: Mesenchymal cells differentiate into osteoblasts, chondrocytes, and osteoclasts.
  • Intramembranous Ossification: Osteoblasts differentiate within mesenchymal or fibrous connective tissue (also called dermis ossification); occurs in deeper layers of the dermis. Results in dermal bones. Examples: flat bones of the skull, facial bones, mandible, medial part of clavicle.

Bone Growth

  • Length: Occurs at the epiphyseal plate.
    • Chondrocytes divide and form columns.
    • Chondrocytes enlarge and produce a calcified matrix.
    • Chondrocytes die because the matrix has calcified.
    • Osteoclasts dissolve the calcified cartilage, and osteoblasts and blood vessels from the diaphysis invade the area to form new bone.
    • After adolescence, the epiphyseal plate becomes ossified, stopping growth.
  • Thickness (Appositional Growth): Occurs at the periosteum.
    • Periosteal cells differentiate into osteoblasts and produce bone matrix, creating ridges around blood vessels.
    • Ridges grow and fuse, forming a canal surrounding the blood vessel. The periosteum becomes endosteum.
    • Osteoblasts of the new endosteum form lamellae, closing the canal.
    • A new osteon is formed, and new circumferential lamellae are formed, creating new ridges.

Anatomy of a Long Bone

  • Epiphysis: Enlarged ends of the bone covered in hyaline cartilage.
  • Diaphysis: Shaft of the bone.
  • Metaphysis: Region between the epiphysis and diaphysis.
  • Periosteum: Tough, fibrous membrane that covers bone.
  • Endosteum: Thin membrane that lines the medullary cavity of the bone.
  • Medullary Cavity: Hollow space in the diaphysis of the bone filled with red marrow in children and yellow marrow in adults.

Structure of Short, Irregular, and Flat Bones

  • Compact Bone: External layers of compact bone covered by periosteum (internal and external tables).
  • Spongy Bone (Diploë): Internal layer of spongy bone covered by endosteum.
  • Bone Marrow: Present but not in a distinct marrow cavity.

Composition of Bone Tissue

  • Extracellular matrix: 15% water, 30% collagen fibers, 55% minerals.
    • Collagen fibers provide elasticity.
    • Mineral salts (hydroxyapatite, calcium phosphate, magnesium, fluoride, potassium, sulfate) provide rigidity.
  • Bone cells:
    • Osteogenic (osteoprogenitor) cells: Unspecialized bone cells; only bone cells that divide; found in the inner and outer lining of bones (endosteum and periosteum).
    • Osteoblasts: Bone-building cells; secrete collagen fibers and initiate calcification; become osteocytes when surrounded by matrix (osteogenesis).
    • Osteocytes: Main cells in healthy bone; involved in maintenance and metabolism.
    • Osteoclasts: Derived from white blood cells; concentrated in the endosteum; active in bone growth, remodeling, and resorption (which regulates calcium levels).

Compact Bone

  • Forms the outer cortex of bone, providing strength and support.
  • Consists of osteons (Haversian systems):
    • Lamellae: Concentric rings of bone matrix.
    • Canaliculi: Tiny canals connecting lacunae.
    • Central canal: Contains blood vessels and nerves.
    • Osteocytes: Bone cells located in lacunae.

Spongy Bone

  • Found internally, reducing the weight of bone.
  • Consists of trabeculae (thin bony plates) that support and protect red bone marrow.
  • Osteocytes in lacunae receive nutrients from blood vessels of the endosteum by diffusion.

Periosteum and Endosteum

  • Periosteum: Outer fibrous layer of bone; important for attachment of muscles, tendons, ligaments; and for nutrient delivery.
  • Endosteum: Single layer of osteoprogenitor cells that lines the medullary cavity and central canals of osteons; active in bone growth and remodeling.

Blood and Nerve Supply

  • Diaphysis: Contains the nutrient foramen (entry point for the nutrient artery and exit point for the nutrient vein).
  • Epiphysis and Metaphysis: Numerous veins and arteries penetrate through foramina.
  • Periosteum: Numerous small blood vessels branch from the nutrient artery and vein.
  • Nerve supply: Follows veins and arteries; sensory nerves; abundant nerve endings in the periosteum and cortical bone make fractures painful.

Forces at Work

  • The structural arrangement of bone tissue reflects the forces it encounters.
  • Compact bone is thicker where forces are greater, and the mesh of spongy bone is oriented to counteract stress.
  • Spongy bone is more appropriate for multidirectional tension.
  • Bones undergo constant remodeling throughout life, adapting to changing forces.

Bone Surface Markings

  • Develop as anchor points for tendons and ligaments as muscles are used (tension and compression forces modify topography).
  • Some markings allow passage of nerves and blood vessels and are present from birth.

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