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Cardiovascular System Medications: RAAS ACE Inhibitors and ARBs

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15 Questions

What is the most serious adverse effect associated with ACE inhibitors?

Angioedema

Which ACE inhibitor is used specifically for the treatment of myocardial infarction (MI)?

Lisinopril

What is the mechanism of action of direct renin inhibitors like aliskiren?

Inhibits the conversion of angiotensinogen to angiotensin I

Which class of antihypertensive drugs is associated with a lower risk of hyperkalemia compared to ACE inhibitors?

Aldosterone antagonists

What is the primary indication for the use of olmesartan?

Hypertension only

Which of the following antihypertensive drug classes is associated with a potential for rebound hypertension if stopped abruptly?

Beta-blockers

Which of the following drug interactions is most concerning with ACE inhibitors?

All of the above

Which of the following statements about eplerenone is correct?

It is a selective aldosterone receptor blocker with fewer side effects than spironolactone

What is the primary mechanism of action of angiotensin converting enzyme (ACE) inhibitors?

All of the above

How do angiotensin receptor blockers (ARBs) differ from ACE inhibitors in their mechanism of action?

ARBs do not inhibit kinase II, so they cause less cough and angioedema than ACE inhibitors

Which of the following is a common adverse effect shared by both ACE inhibitors and ARBs?

Diarrhea

Which patient population is most appropriate for treatment with ACE inhibitors or ARBs compared to beta blockers?

Patients with asthma

What is the primary difference in the syllable structure of ACE inhibitor and ARB drug names?

ACE inhibitors end in '-ipril', while ARBs end in '-artan'

What is a major therapeutic use of ACE inhibitors and ARBs beyond just treating hypertension?

Reducing the risk of cardiovascular mortality and morbidity

What is a common adverse effect that can occur with the first dose of ACE inhibitors or ARBs, especially in patients also taking diuretics?

First-dose hypotension

Learn about the Renin-Angiotensin-Aldosterone System (RAAS), including the mechanisms of action of Angiotensin Converting Enzyme Inhibitors (ACE Inhibitors) and Angiotensin Receptor Blockers (ARBs). Understand how these medications reduce angiotensin II levels, dilate blood vessels, and block receptors to treat cardiovascular conditions.

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