Cardiovascular System Medications: RAAS ACE Inhibitors and ARBs
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Questions and Answers

What is the most serious adverse effect associated with ACE inhibitors?

  • Renal failure
  • Angioedema (correct)
  • Hyperkalemia
  • Hypotension

    • Which ACE inhibitor is used specifically for the treatment of myocardial infarction (MI)?

  • Losartan
  • Lisinopril (correct)
  • Captopril
  • Enalapril

    • What is the mechanism of action of direct renin inhibitors like aliskiren?

  • Increases the production of angiotensin-converting enzyme
  • Stimulates the release of aldosterone from the adrenal glands
  • Inhibits the conversion of angiotensinogen to angiotensin I (correct)
  • Blocks the binding of angiotensin II to AT1 receptors

    • Which class of antihypertensive drugs is associated with a lower risk of hyperkalemia compared to ACE inhibitors?

    <p>Aldosterone antagonists</p> Signup and view all the answers

    What is the primary indication for the use of olmesartan?

    <p>Hypertension only</p> Signup and view all the answers

    Which of the following antihypertensive drug classes is associated with a potential for rebound hypertension if stopped abruptly?

    <p>Beta-blockers</p> Signup and view all the answers

    Which of the following drug interactions is most concerning with ACE inhibitors?

    <p>All of the above</p> Signup and view all the answers

    Which of the following statements about eplerenone is correct?

    <p>It is a selective aldosterone receptor blocker with fewer side effects than spironolactone</p> Signup and view all the answers

    What is the primary mechanism of action of angiotensin converting enzyme (ACE) inhibitors?

    <p>All of the above</p> Signup and view all the answers

    How do angiotensin receptor blockers (ARBs) differ from ACE inhibitors in their mechanism of action?

    <p>ARBs do not inhibit kinase II, so they cause less cough and angioedema than ACE inhibitors</p> Signup and view all the answers

    Which of the following is a common adverse effect shared by both ACE inhibitors and ARBs?

    <p>Diarrhea</p> Signup and view all the answers

    Which patient population is most appropriate for treatment with ACE inhibitors or ARBs compared to beta blockers?

    <p>Patients with asthma</p> Signup and view all the answers

    What is the primary difference in the syllable structure of ACE inhibitor and ARB drug names?

    <p>ACE inhibitors end in '-ipril', while ARBs end in '-artan'</p> Signup and view all the answers

    What is a major therapeutic use of ACE inhibitors and ARBs beyond just treating hypertension?

    <p>Reducing the risk of cardiovascular mortality and morbidity</p> Signup and view all the answers

    What is a common adverse effect that can occur with the first dose of ACE inhibitors or ARBs, especially in patients also taking diuretics?

    <p>First-dose hypotension</p> Signup and view all the answers

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