Cardiovascular System Medications: RAAS and ACE Inhibitors Quiz

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What is the mechanism of action of quinidine?

Inhibits metabolism leading to increased toxicity (correct)
Works on smooth muscle to promote dilation of veins
Directly promotes dilation of veins
Causes reflex tachycardia

Which adverse effect is a unique concern for African American population when using quinidine?

Headache
Lupus-like syndrome (correct)
Sudden severe pain
Anorexia

What is the primary use of organic nitrates like nitroglycerin?

To cause reflex tachycardia
To decrease O2 demand in the body (correct)
To increase O2 demand in the body
To prevent anorexia

What is a common side effect of quinidine toxicity that serves as an early warning sign?

Anorexia (B) Signup and view all the answers

How does grapefruit juice impact drug interactions with certain medications?

Inhibits metabolism leading to increased toxicity (D) Signup and view all the answers

What is the main effect of organic nitrates like nitroglycerin on blood vessels?

Causes dilation of veins (B) Signup and view all the answers

What is the primary mechanism of action of angiotensin converting enzyme (ACE) inhibitors?

Reduces levels of angiotensin II, which dilates blood vessels (C) Signup and view all the answers

How do angiotensin receptor blockers (ARBs) differ from ACE inhibitors in their mechanism of action?

ARBs block the receptors for angiotensin II, while ACE inhibitors reduce the production of angiotensin II (D) Signup and view all the answers

What is the primary advantage of ARBs over ACE inhibitors?

ARBs are less likely to cause cough and angioedema (A) Signup and view all the answers

How do ACE inhibitors and ARBs both affect the renin-angiotensin-aldosterone system (RAAS)?

ACE inhibitors and ARBs both decrease RAAS activity (B) Signup and view all the answers

What is the primary difference between the effects of ACE inhibitors and ARBs on bradykinin levels?

ACE inhibitors increase bradykinin levels, while ARBs do not (A) Signup and view all the answers

What is the primary reason ACE inhibitors may be preferred over ARBs in some patients?

ACE inhibitors are less likely to cause first-dose hypotension (C) Signup and view all the answers

What is the primary mechanism of action for calcium channel blockers (CCBs)?

Preventing calcium from entering cells, especially in the heart and blood vessels (C) Signup and view all the answers

Which of the following is NOT a therapeutic use of calcium channel blockers?

Hyperkalemia (B) Signup and view all the answers

What is the primary effect of preventing calcium entry into cardiac cells?

Decreased heart rate and decreased myocardial contraction (B) Signup and view all the answers

Which of the following is NOT a common adverse effect associated with calcium channel blockers?

Hyperkalemia (B) Signup and view all the answers

Which of the following calcium channel blockers primarily affects the heart?

Verapamil (D) Signup and view all the answers

What is the primary mechanism by which calcium channel blockers cause vasodilation?

Inhibiting calcium entry into vascular smooth muscle cells (C) Signup and view all the answers