Cardiovascular Physiology: Preload Factors
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Questions and Answers

Filling time, which is determined by the ______ rate, affects the preload immensely.

heart

Increased ______ will result in an increased atrial contractility, which will then cause an increase in ventricular filling.

atrial pressure

Ventricular ______ is the ventricle's capacity to generate force.

contractility

Increased ______ refers to the increased force at any given end diastolic volume.

<p>contractility</p> Signup and view all the answers

Without changing the end diastolic volume, we can increase the force at contractions through ______ innervation and circulating epinephrine.

<p>sympathetic</p> Signup and view all the answers

Increasing the amount of blood in the ventricle would stretch it out, putting the sarcomeres of their ______ length, and allowing them to contract with a greater force.

<p>ideal</p> Signup and view all the answers

An increase in end-diastolic volume will cause an increase in ______ volume.

<p>stroke</p> Signup and view all the answers

Stroke volume increases when end-diastolic volume increases because the cardiac muscle fibers contract more ______.

<p>forcefully</p> Signup and view all the answers

Increased sympathetic activity increases ______ volume, shifting the entire Starling curve up.

<p>stroke</p> Signup and view all the answers

Decreased sympathetic activity decreases ______ volume, shifting the entire Starling curve down.

<p>stroke</p> Signup and view all the answers

When the end-diastolic volume is greater, the myocardium ______ out.

<p>stretches</p> Signup and view all the answers

End diastolic volume is primarily determined by the end diastolic ______ (or preload).

<p>pressure</p> Signup and view all the answers

Epinephrine and norepinephrine bind to beta-1 adrenergic receptors in the heart, increasing ______ and the rate of crossbridge cycling.

<p>cAMP</p> Signup and view all the answers

Enhanced presence of Ca2+ results in increased ______ at end-diastolic volume.

<p>contractility</p> Signup and view all the answers

Afterload is the pressure that the ventricles have to work against to expel blood from the heart. It is impacted by the pressure of the ______.

<p>arteries</p> Signup and view all the answers

As mean arterial pressure (MAP) increases, afterload also ______.

<p>increases</p> Signup and view all the answers

Hypertension makes the heart pump harder to get the same volume of blood to the rest of the body, thus increasing the ______ on the heart.

<p>pressure</p> Signup and view all the answers

To demonstrate the idea of afterload, think about someone pushing a boulder up a steep hill. In this analogy, the person is like the ventricles pushing blood through the blood vessels, and gravity is the ______.

<p>afterload</p> Signup and view all the answers

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