Podcast
Questions and Answers
Nitroglycerin is a prodrug that is converted by mitochondrial aldehyde dehydrogenase to give nitric oxide.
Nitroglycerin is a prodrug that is converted by mitochondrial aldehyde dehydrogenase to give nitric oxide.
True
Propranolol is a selective β-agonist used for the treatment of glaucoma.
Propranolol is a selective β-agonist used for the treatment of glaucoma.
False
Propranolol's route of administration is mainly intravenous due to its high first-pass metabolism.
Propranolol's route of administration is mainly intravenous due to its high first-pass metabolism.
False
Nitroglycerin causes blood vessels dilation by inhibiting smooth muscle contraction.
Nitroglycerin causes blood vessels dilation by inhibiting smooth muscle contraction.
Signup and view all the answers
Heparin has a longer half-life compared to Propranolol.
Heparin has a longer half-life compared to Propranolol.
Signup and view all the answers
Digitalis is commonly used to treat hypertension and bronchoconstriction.
Digitalis is commonly used to treat hypertension and bronchoconstriction.
Signup and view all the answers
Digitalis is extracted from the sunflower plant.
Digitalis is extracted from the sunflower plant.
Signup and view all the answers
CCF stands for Congenital Cardiac Failure.
CCF stands for Congenital Cardiac Failure.
Signup and view all the answers
Digoxin acts mainly on the lungs in the treatment of congestive cardiac failure.
Digoxin acts mainly on the lungs in the treatment of congestive cardiac failure.
Signup and view all the answers
Aspirin prevents clotting of blood by promoting platelet activation and aggregation.
Aspirin prevents clotting of blood by promoting platelet activation and aggregation.
Signup and view all the answers
Digoxin is excreted via the liver.
Digoxin is excreted via the liver.
Signup and view all the answers
The onset of aspirin when taken orally is typically 1-2 hours.
The onset of aspirin when taken orally is typically 1-2 hours.
Signup and view all the answers
Warfarin is structurally related to vitamin C.
Warfarin is structurally related to vitamin C.
Signup and view all the answers
Heparin-induced Thrombocytopenia (HIT) always leads to amputations.
Heparin-induced Thrombocytopenia (HIT) always leads to amputations.
Signup and view all the answers
Aspirin inhibits blood clot formation by inactivating clotting factors.
Aspirin inhibits blood clot formation by inactivating clotting factors.
Signup and view all the answers
Heparin is safe to use in pregnancy due to its low therapeutic index.
Heparin is safe to use in pregnancy due to its low therapeutic index.
Signup and view all the answers
The antidote for heparin-induced thrombocytopenia is vitamin K.
The antidote for heparin-induced thrombocytopenia is vitamin K.
Signup and view all the answers
Warfarin-induced skin necrosis is most likely to occur in postmenopausal obese women.
Warfarin-induced skin necrosis is most likely to occur in postmenopausal obese women.
Signup and view all the answers
Propranolol increases heart rate and force of contraction by inhibiting smooth muscle contraction.
Propranolol increases heart rate and force of contraction by inhibiting smooth muscle contraction.
Signup and view all the answers
Nitroglycerin dilates blood vessels by promoting smooth muscle relaxation.
Nitroglycerin dilates blood vessels by promoting smooth muscle relaxation.
Signup and view all the answers
Digitalis is commonly used for the treatment of glaucoma.
Digitalis is commonly used for the treatment of glaucoma.
Signup and view all the answers
Heparin has a shorter half-life compared to Nitroglycerin.
Heparin has a shorter half-life compared to Nitroglycerin.
Signup and view all the answers
Warfarin is structurally related to vitamin K.
Warfarin is structurally related to vitamin K.
Signup and view all the answers
Aspirin prevents clotting of blood by inactivating clotting factors.
Aspirin prevents clotting of blood by inactivating clotting factors.
Signup and view all the answers
Aspirin is used at low doses to inhibit PGI2 formation in endothelium.
Aspirin is used at low doses to inhibit PGI2 formation in endothelium.
Signup and view all the answers
Heparin and Low Molecular Weight Heparin (LMWH) prevent clotting of blood by activating clotting factors.
Heparin and Low Molecular Weight Heparin (LMWH) prevent clotting of blood by activating clotting factors.
Signup and view all the answers
Warfarin is a vitamin K antagonist that prevents the synthesis of clotting factors II, VII, IX, and X.
Warfarin is a vitamin K antagonist that prevents the synthesis of clotting factors II, VII, IX, and X.
Signup and view all the answers
Heparins are primarily given intramuscularly.
Heparins are primarily given intramuscularly.
Signup and view all the answers
The antidote for heparin-induced thrombocytopenia is protamine sulphate.
The antidote for heparin-induced thrombocytopenia is protamine sulphate.
Signup and view all the answers
Warfarin-induced skin necrosis is most likely to occur in young males.
Warfarin-induced skin necrosis is most likely to occur in young males.
Signup and view all the answers
Digoxin is the main drug in the class of Cardiac Glycosides.
Digoxin is the main drug in the class of Cardiac Glycosides.
Signup and view all the answers
Digoxin primarily acts on the heart and is used in the treatment of congestive cardiac failure (CCF).
Digoxin primarily acts on the heart and is used in the treatment of congestive cardiac failure (CCF).
Signup and view all the answers
Hypertensive emergency is not a clinical use of Digoxin.
Hypertensive emergency is not a clinical use of Digoxin.
Signup and view all the answers
Aspirin's onset when taken orally is 30-60 minutes.
Aspirin's onset when taken orally is 30-60 minutes.
Signup and view all the answers
Aspirin prevents clotting of blood by irreversibly inhibiting the cyclooxygenase (COX) enzyme.
Aspirin prevents clotting of blood by irreversibly inhibiting the cyclooxygenase (COX) enzyme.
Signup and view all the answers
Platelet activation and aggregation are prevented by aspirin through its effect on thromboxane A2 synthesis.
Platelet activation and aggregation are prevented by aspirin through its effect on thromboxane A2 synthesis.
Signup and view all the answers
