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Questions and Answers
Nitroglycerin is a prodrug that is converted by mitochondrial aldehyde dehydrogenase to give nitric oxide.
True
Propranolol is a selective β-agonist used for the treatment of glaucoma.
False
Propranolol's route of administration is mainly intravenous due to its high first-pass metabolism.
False
Nitroglycerin causes blood vessels dilation by inhibiting smooth muscle contraction.
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Heparin has a longer half-life compared to Propranolol.
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Digitalis is commonly used to treat hypertension and bronchoconstriction.
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Digitalis is extracted from the sunflower plant.
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CCF stands for Congenital Cardiac Failure.
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Digoxin acts mainly on the lungs in the treatment of congestive cardiac failure.
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Aspirin prevents clotting of blood by promoting platelet activation and aggregation.
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Digoxin is excreted via the liver.
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The onset of aspirin when taken orally is typically 1-2 hours.
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Warfarin is structurally related to vitamin C.
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Heparin-induced Thrombocytopenia (HIT) always leads to amputations.
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Aspirin inhibits blood clot formation by inactivating clotting factors.
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Heparin is safe to use in pregnancy due to its low therapeutic index.
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The antidote for heparin-induced thrombocytopenia is vitamin K.
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Warfarin-induced skin necrosis is most likely to occur in postmenopausal obese women.
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Propranolol increases heart rate and force of contraction by inhibiting smooth muscle contraction.
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Nitroglycerin dilates blood vessels by promoting smooth muscle relaxation.
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Digitalis is commonly used for the treatment of glaucoma.
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Heparin has a shorter half-life compared to Nitroglycerin.
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Warfarin is structurally related to vitamin K.
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Aspirin prevents clotting of blood by inactivating clotting factors.
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Aspirin is used at low doses to inhibit PGI2 formation in endothelium.
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Heparin and Low Molecular Weight Heparin (LMWH) prevent clotting of blood by activating clotting factors.
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Warfarin is a vitamin K antagonist that prevents the synthesis of clotting factors II, VII, IX, and X.
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Heparins are primarily given intramuscularly.
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The antidote for heparin-induced thrombocytopenia is protamine sulphate.
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Warfarin-induced skin necrosis is most likely to occur in young males.
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Digoxin is the main drug in the class of Cardiac Glycosides.
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Digoxin primarily acts on the heart and is used in the treatment of congestive cardiac failure (CCF).
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Hypertensive emergency is not a clinical use of Digoxin.
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Aspirin's onset when taken orally is 30-60 minutes.
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Aspirin prevents clotting of blood by irreversibly inhibiting the cyclooxygenase (COX) enzyme.
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Platelet activation and aggregation are prevented by aspirin through its effect on thromboxane A2 synthesis.
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