18 Questions
What is the main clinical use of digoxin?
Treatment of congestive cardiac failure
Which adverse effect is commonly associated with digoxin use?
Hypokalemia
What is the mechanism of action of aspirin?
Reduction of prostaglandin synthesis
Which enzyme does digoxin inhibit to increase intracellular calcium concentrations?
Na+/K+ ATPase pump
What is the primary role of aspirin in platelet function?
Inhibition of thromboxane A2 production
Which of the following medications interacts negatively with digoxin?
NSAIDs
Why is aspirin used at low doses?
To prevent platelet aggregation by inhibiting PGI2 formation
What is the primary mechanism of action of heparins?
Inactivation of clotting factors IIa, IXa, Xa, XIa, XIIa
What is the antidote for heparin-induced thrombocytopenia?
Protamine sulfate
How does warfarin function as an anticoagulant?
Inhibits the synthesis of clotting factors II, VII, IX, X
What is monitored when using warfarin as an anticoagulant?
Prothrombin time (PT), international normalized ratio (INR)
What causes warfarin-induced skin necrosis?
A rare, serious adverse drug reaction to warfarin
What is the primary mechanism of action of Propranolol?
Inhibits the contraction of the heart by blocking β1 receptors
Which of the following is NOT a major adverse effect of Propranolol?
Hypertension
What is the primary effect of Nitroglycerin on blood vessels?
Relaxation of smooth muscle leading to vasodilation
What is the role of mitochondrial aldehyde dehydrogenase (MtALDH) in the action of Nitroglycerin?
Convert Nitroglycerin to NO
What is the half-life of Propranolol?
4 hours
What is the peak concentration time of Nitroglycerin when administered intravenously?
Approximately 4.4 minutes
Learn about various cardiovascular drugs such as Propranolol, Nitroglycerin, Digitalis, Aspirin, Heparin, and Warfarin with their respective functions and mechanisms of action. This quiz covers the basics of how these drugs affect the cardiovascular system.
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