10 Questions
What is the significance of elevated CK-MB levels above 5% MB in a patient?
It can indicate myocardial infarction.
What might be a reason for elevated cTnT levels in the absence of acute coronary syndrome?
Chronic renal failure (CRF).
Why is cTnI considered the most cardiac specific biomarker?
Because it is not elevated by chronic renal failure (CRF).
What is the normal range for myoglobin in the blood?
< 85 ng/ml.
Which cardiac biomarker has a normal range of < 0.1 ng/ml?
Troponin I (cTnI).
How long does it take for MB-Ck to return to normal levels after it initially elevates?
2 - 3 days
What is the peak time for Troponin T elevation?
12 - 24 hours
For how long can Troponin I levels remain elevated before returning to normal?
5 - 10 days
Within what time frame does Lactate dehydrogenase (LDH) initially elevate?
6 - 12 hours
How long after an AST (SGOT) elevation does it take for it to return to normal?
After 5 days
Study Notes
Cardiac Enzymes (Biomarkers)
-
CK-MB:
- Normally has less than 5% MB
- Normal level is less than 85 ng/ml
Myoglobin
- Normal level is less than 85 ng/ml
Troponin
-
cTnT:
- Normal level is less than 0.01 ng/ml
- May be elevated in cases of Chronic Renal Failure (CRF)
-
Troponin I:
- Normal level is less than 0.1 ng/ml
- Not elevated in cases of Chronic Renal Failure (CRF)
- Most cardiac specific
Time Course of Cardiac Biomarkers
CK-MB
- Initial elevation occurs between 3-12 hours
- Peaks at 24 hours
- Returns to normal in 2-3 days
Troponin I
- Initial elevation occurs between 3-12 hours
- Peaks at 24 hours
- Returns to normal in 5-10 days
Troponin T
- Initial elevation occurs between 3-12 hours
- Peaks at 12-24 hours
- Returns to normal in 5-14 days
AST (SGOT)
- Initial elevation occurs within a few hours (6-12 hours)
- Peaks at 36 hours
- Returns to normal after 5 days
Lactate Dehydrogenase (LDH)
- Initial elevation occurs within a few hours (6-12 hours)
- Peaks at 3 days
- Returns to normal after 1 week
This quiz covers the normal values of cardiac enzymes, including CK-MB, Myoglobin, Troponin, cTnT, and Troponin I, which are biomarkers used to diagnose cardiac conditions.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
