Cancer and Contraception

Questions and Answers

What is a common clinical use of Ketoconazole?

Management of androgenic alopecia

Treatment of benign prostatic hyperplasia (BPH)

Treatment of prostate cancer (correct)

Reduction of sexual dysfunction

Which side effect is associated with Spironolactone?

Increased blood pressure

Severe headaches

Weight gain

Amenorrhea (correct)

What is the primary mechanism of action for Tamsulosin?

Aromatase inhibitor

Beta-agonist

Alpha-adrenergic antagonist (correct)

Calcium channel blocker

Which condition is Minoxidil primarily indicated for?

Severe refractory hypertension Signup and view all the answers

What side effect is commonly linked to the use of Ketoconazole?

Gynecomastia Signup and view all the answers

Which of the following is NOT a side effect of Minoxidil?

Weight loss Signup and view all the answers

Which treatment is primarily used for benign prostatic hyperplasia (BPH)?

Tamsulosin Signup and view all the answers

What is a common indication for the use of Spironolactone?

Androgenic alopecia Signup and view all the answers

Which condition is treated with both Ketoconazole and Spironolactone?

Gynecomastia Signup and view all the answers

Which is a clinical use of Spironolactone?

Treatment of polycystic ovarian syndrome (PCOS) Signup and view all the answers

What is a common side effect of Gonadotropin-Releasing Hormone (GnRH) Antagonists?

Hot flushes Signup and view all the answers

Which of the following is an indication for the use of synthetic estrogens like ethinyl estradiol?

Hormone Replacement Therapy Signup and view all the answers

Which condition is NOT typically associated with the use of Indomethacin?

Osteoporosis Signup and view all the answers

What type of cancer has been associated with increased risk due to hormone replacement therapy?

Clear cell adenocarcinoma of the vagina Signup and view all the answers

What is a contraindication for the use of estrogens in women?

Over 35 years old and tobacco use Signup and view all the answers

Which of the following hormonal therapies is indicated for the treatment of endometriosis?

GnRH Antagonists Signup and view all the answers

What is the primary mechanism of action of GnRH antagonists?

Inhibiting hormone secretion Signup and view all the answers

Which of the following is NOT a side effect of synthetic estrogens?

Respiratory depression Signup and view all the answers

In which patient population is hormone replacement therapy primarily indicated?

Postmenopausal women Signup and view all the answers

What potential side effect could result from the use of synthetic estrogens?

Bone density loss Signup and view all the answers

Which medication is indicated for the treatment of endometriosis?

Danazol Signup and view all the answers

What is a common side effect of Indomethacin?

Gastrointestinal bleeding Signup and view all the answers

Which of the following is a side effect of full androgen receptor agonists?

Premature closure of epiphyseal plate Signup and view all the answers

What is the mechanism of action of tocolytics such as Nifedipine?

Calcium channel blocker Signup and view all the answers

Which of the following is NOT a side effect associated with Partial Androgen Receptor Agonists?

Idiopathic weight loss Signup and view all the answers

Which indication is associated with the use of copper intrauterine devices?

Emergency contraception Signup and view all the answers

Which of the following can be a contraindication for combined contraception?

History of liver disease Signup and view all the answers

Which side effect is associated with hormone replacement therapy?

Endometrial cancer risk Signup and view all the answers

What is a potential consequence of long-term use of androgen receptor antagonists like Finasteride?

Increased LDL levels Signup and view all the answers

What is the primary indication for using tocolytics?

Maintaining pregnancy by preventing premature labor Signup and view all the answers

Which condition might a combined hormonal contraceptive be contraindicated for?

A history of migraines with aura Signup and view all the answers

What is a side effect of emergency contraception like Ulipristal?

Menstrual cycle disruption Signup and view all the answers

Which androgen receptor antagonist is known for treating prostate cancer?

Flutamide Signup and view all the answers

What is the primary action of copper intrauterine devices?

Creating a cytotoxic environment for sperm Signup and view all the answers

Which condition is primarily indicated for Gonadotropin-Releasing Hormone (GnRH) Antagonists?

Prostate cancer Signup and view all the answers

What is a common side effect associated with Synthetic Estrogens like Ethinyl Estradiol?

Hot flushes Signup and view all the answers

Which of the following is a contraindication for hormone replacement therapy?

Exposure to diethylbestrol in utero Signup and view all the answers

What increased risk is associated with hormone replacement therapy in females?

Clear cell adenocarcinoma of vagina Signup and view all the answers

Which side effect is linked to the use of Gonadotropin-Releasing Hormone (GnRH) Antagonist?

Hot flushes Signup and view all the answers

In which patient population are Synthetic Estrogens most commonly indicated?

Menopausal women for HRT Signup and view all the answers

Which of the following conditions is NOT commonly treated with hormone-related therapies?

Acne Signup and view all the answers

What potential side effect could occur from hormone replacement therapy?

Clear cell adenocarcinoma Signup and view all the answers

What is a side effect that is commonly associated with hormone replacement therapy in postmenopausal women?

Increased risk of clear cell adenocarcinoma Signup and view all the answers

Which indication is associated with the use of Synthetic Estrogens?

Hormone Replacement Therapy Signup and view all the answers

Which of the following medications is primarily indicated for Benign Prostatic Hyperplasia (BPH)?

Tamsulosin Signup and view all the answers

What side effect is commonly associated with the use of Ketoconazole?

Gynecomastia Signup and view all the answers

Which medication can cause sexual dysfunction as a side effect?

Spironolactone Signup and view all the answers

What is a common clinical use for Spironolactone?

Androgenic alopecia Signup and view all the answers

Minoxidil is primarily used for which of the following conditions?

Severe refractory hypertension Signup and view all the answers

Which of the following best describes a side effect of Minoxidil?

Hypotension Signup and view all the answers

What uncommon side effect may occur with prolonged use of Tamsulosin?

Ejaculation failure Signup and view all the answers

In which condition is Spironolactone NOT typically used?

Hypokalemia Signup and view all the answers

What is a major clinical use of Ketoconazole?

Fungal infections Signup and view all the answers

Which side effect may be associated with increased use of Tamsulosin?

Orthostatic hypotension Signup and view all the answers

Which side effect is commonly associated with the use of combined contraception?

Endometrial cancer risk Signup and view all the answers

Which of the following is an indication for the use of anti-progestins?

Emergency contraception Signup and view all the answers

What side effect is associated with the use of copper intrauterine devices?

Increased risk of pelvic inflammatory disease Signup and view all the answers

Which condition could be a contraindication for using hormone replacement therapy?

Breast cancer history Signup and view all the answers

Which of the following side effects is linked to androgen receptor antagonists like Abiraterone?

Weight gain Signup and view all the answers

What is a common indication for the use of tocolytics?

Preterm labor Signup and view all the answers

Which side effect is associated with the use of partial androgen receptor agonists?

Premature epiphyseal closure Signup and view all the answers

Which of the following medications is indicated for the treatment of endometriosis?

Danazol Signup and view all the answers

Which side effect is commonly experienced by individuals taking full androgen receptor agonists?

Hirsutism Signup and view all the answers

Which of the following is a side effect of hormone replacement therapy?

Increased risk of cardiovascular disease Signup and view all the answers

Which of the following conditions are treated with tocolytics such as Terbutaline?

Preterm labor Signup and view all the answers

Which of the following conditions indicates the need for copper intrauterine devices?

Long-term contraception Signup and view all the answers

What is the primary side effect associated with the use of tocolytics?

Hypokalemia Signup and view all the answers

What is a common indication for the use of Bicalutamide?

Prostate cancer Signup and view all the answers

Which side effect is frequently associated with Ketoconazole?

Gynecomastia Signup and view all the answers

What condition is Tamsulosin primarily used to treat?

Benign Prostatic Hyperplasia Signup and view all the answers

What common clinical use does Spironolactone have?

Treatment of Poly Cystic Ovarian Syndrome Signup and view all the answers

Which of the following is a well-known side effect of Minoxidil?

Severe refractory hypertension Signup and view all the answers

Which condition might result from the use of Tamsulosin?

Sexual dysfunction Signup and view all the answers

What is a clinical use of Minoxidil?

Androgenic alopecia Signup and view all the answers

Which of the following medications can cause gynecomastia as a side effect?

Spironolactone Signup and view all the answers

Which side effect is most likely associated with Spironolactone?

Amenorrhea Signup and view all the answers

What is a common application of Ketoconazole in a clinical setting?

Therapy for gynecomastia Signup and view all the answers

What condition is an indication for the use of Gonadotropin-Releasing Hormone (GnRH) Antagonists?

Endometriosis Signup and view all the answers

Which side effect is commonly associated with synthetic estrogens like ethinyl estradiol?

Liver toxicity Signup and view all the answers

Which of the following is a contraindication for hormone replacement therapy?

Previous breast cancer Signup and view all the answers

What is a common side effect of hormone replacement therapy in postmenopausal women?

Hot flushes Signup and view all the answers

What increased risk is associated with hormone replacement therapy for women?

Clear cell adenocarcinoma of the vagina Signup and view all the answers

Which condition is commonly treated with synthetic estrogens?

Hormone Replacement Therapy (HRT) Signup and view all the answers

Which of the following is a side effect of the use of Gonadotropin-Releasing Hormone (GnRH) Antagonists?

Flushing Signup and view all the answers

What condition could be a contraindication for synthetic estrogens?

History of thromboembolic disorders Signup and view all the answers

In which patient population are synthetic estrogens most commonly indicated?

Postmenopausal women Signup and view all the answers

What is a potential side effect of hormone replacement therapy?

Mood swings Signup and view all the answers

What is a common indication for the use of anti-progestins?

Emergency contraception Signup and view all the answers

Which side effect is commonly associated with combined contraception?

Breakthrough menstrual bleeding Signup and view all the answers

What is a contraindication for the use of hormone replacement therapy?

Liver disease Signup and view all the answers

Which side effect can occur with the use of tocolytics like Terbutaline?

Palpitations Signup and view all the answers

What is a common indication for copper intrauterine devices?

Long lasting reversible contraception Signup and view all the answers

Which condition is treated with tocolytics?

Labor complications Signup and view all the answers

Which side effect is notably linked to oral contraceptives?

Venous thromboembolism Signup and view all the answers

What is a common indication for partial androgen receptor agonists?

Hereditary angioedema Signup and view all the answers

Which condition is NOT associated with hormone replacement therapy?

Infertility management Signup and view all the answers

What side effect is common in patients taking full androgen receptor agonists?

Premature epiphyseal closure Signup and view all the answers

Which medication is indicated for the treatment of endometriosis?

Danazol Signup and view all the answers

What is a side effect associated with the use of mifepristone?

Nausea and vomiting Signup and view all the answers

Which side effect is commonly linked to the use of Nifedipine as a tocolytic?

Facial flushing Signup and view all the answers

What is a significant contraindication for using hormone replacement therapy in women?

Previous blood clot history Signup and view all the answers

Study Notes

Contraceptive Methods

Anti-progestins: Used for termination of pregnancy and emergency contraception.
Examples: Ulipristal and Mifepristone.

Combined Contraception

Components: Ethinyl Estradiol and Progestin.
Indications: Hormone Replacement Therapy (HRT) for postmenopausal women, menstrual abnormalities, hypogonadism, and ovarian failure.
Side Effects: Increased endometrial cancer risk, breakthrough bleeding, venous thromboembolism, hepatic adenoma.
Contraindications: Cardiovascular disease history, breast cancer history, liver disease, migraines, age above 35, and smoking.

Copper Intrauterine Device

Action: Long-lasting reversible contraception, most effective for emergency use.
Indications: Heavy menstrual bleeding and dysmenorrhea.
Contraindications: Pelvic inflammatory disease (PID).

Tocolytics

Purpose: Used to delay preterm labor.
Examples:
- Terbutaline - β2 agonist.
- Nifedipine - Ca2+ channel blocker.
- Indomethacin - NSAID.

Partial Androgen Receptor Agonists

Indications: Treat hereditary angioedema and endometriosis.
Side Effects: Idiopathic intracranial hypertension, decreased HDL levels, masculinization, hepatotoxicity, weight gain, hirsutism, edema, and acne.
Example: Danazol.

Full Androgen Receptor Agonists

Indications: Promote development of secondary sexual characteristics and treat hypogonadism.
Side Effects: Increased LDL and decreased HDL levels, testicular hypertrophy, and virilization in females.

Androgen Receptor Antagonists

Clinical Use: Treat prostate cancer and benign prostatic hyperplasia (BPH).
Examples:
- Abiraterone - used for prostate cancer.
- Finasteride - used for BPH, can cause hypertension, and sexual dysfunction.
- Flutamide and Bicalutamide - used for various cancers, with potential side effects like nausea and vomiting.

Gonadotropin-Releasing Hormone (GnRH) Antagonist

Usage: Primarily for prostate cancer treatment.
Side Effects: Hot flushes and potential liver toxicity.
Example: Degarelix.

Synthetic Estrogens

Indications: Hormone Replacement Therapy (HRT) for postmenopausal women.
Side Effects: Increased risk of clear cell adenocarcinoma of the vagina, particularly in women exposed to diethylstilbestrol (DES) in utero.
Contraindications: Tobacco use in females over 35 years old.### Bicalutamide
Indicated for prostate cancer treatment.
Associated side effect: gynecomastia.

Ketoconazole

Used in the management of prostate cancer.
Known side effects include sexual dysfunction.

Spironolactone

Utilized for conditions such as polycystic ovarian syndrome (PCOS).
Side effects include gynecomastia and amenorrhea.

Tamsulosin

Mechanism of action primarily targets benign prostatic hyperplasia (BPH).
Facilitates urination by relaxing prostate and bladder neck muscles.

Minoxidil

Primarily treats androgenic alopecia to promote hair growth.
Used for severe refractory hypertension, acting as a potent vasodilator.

Contraceptive Methods

Anti-progestins: Used for termination of pregnancy and emergency contraception.
Examples: Ulipristal and Mifepristone.

Combined Contraception

Components: Ethinyl Estradiol and Progestin.
Indications: Hormone Replacement Therapy (HRT) for postmenopausal women, menstrual abnormalities, hypogonadism, and ovarian failure.
Side Effects: Increased endometrial cancer risk, breakthrough bleeding, venous thromboembolism, hepatic adenoma.
Contraindications: Cardiovascular disease history, breast cancer history, liver disease, migraines, age above 35, and smoking.

Copper Intrauterine Device

Action: Long-lasting reversible contraception, most effective for emergency use.
Indications: Heavy menstrual bleeding and dysmenorrhea.
Contraindications: Pelvic inflammatory disease (PID).

Tocolytics

Purpose: Used to delay preterm labor.
Examples:
- Terbutaline - β2 agonist.
- Nifedipine - Ca2+ channel blocker.
- Indomethacin - NSAID.

Partial Androgen Receptor Agonists

Indications: Treat hereditary angioedema and endometriosis.
Side Effects: Idiopathic intracranial hypertension, decreased HDL levels, masculinization, hepatotoxicity, weight gain, hirsutism, edema, and acne.
Example: Danazol.

Full Androgen Receptor Agonists

Indications: Promote development of secondary sexual characteristics and treat hypogonadism.
Side Effects: Increased LDL and decreased HDL levels, testicular hypertrophy, and virilization in females.

Androgen Receptor Antagonists

Clinical Use: Treat prostate cancer and benign prostatic hyperplasia (BPH).
Examples:
- Abiraterone - used for prostate cancer.
- Finasteride - used for BPH, can cause hypertension, and sexual dysfunction.
- Flutamide and Bicalutamide - used for various cancers, with potential side effects like nausea and vomiting.

Gonadotropin-Releasing Hormone (GnRH) Antagonist

Usage: Primarily for prostate cancer treatment.
Side Effects: Hot flushes and potential liver toxicity.
Example: Degarelix.

Synthetic Estrogens

Indications: Hormone Replacement Therapy (HRT) for postmenopausal women.
Side Effects: Increased risk of clear cell adenocarcinoma of the vagina, particularly in women exposed to diethylstilbestrol (DES) in utero.
Contraindications: Tobacco use in females over 35 years old.### Bicalutamide
Indicated for prostate cancer treatment.
Associated side effect: gynecomastia.

Ketoconazole

Used in the management of prostate cancer.
Known side effects include sexual dysfunction.

Spironolactone

Utilized for conditions such as polycystic ovarian syndrome (PCOS).
Side effects include gynecomastia and amenorrhea.

Tamsulosin

Mechanism of action primarily targets benign prostatic hyperplasia (BPH).
Facilitates urination by relaxing prostate and bladder neck muscles.

Minoxidil

Primarily treats androgenic alopecia to promote hair growth.
Used for severe refractory hypertension, acting as a potent vasodilator.

Contraceptive Methods

Anti-progestins: Used for termination of pregnancy and emergency contraception.
Examples: Ulipristal and Mifepristone.

Combined Contraception

Components: Ethinyl Estradiol and Progestin.
Indications: Hormone Replacement Therapy (HRT) for postmenopausal women, menstrual abnormalities, hypogonadism, and ovarian failure.
Side Effects: Increased endometrial cancer risk, breakthrough bleeding, venous thromboembolism, hepatic adenoma.
Contraindications: Cardiovascular disease history, breast cancer history, liver disease, migraines, age above 35, and smoking.

Copper Intrauterine Device

Action: Long-lasting reversible contraception, most effective for emergency use.
Indications: Heavy menstrual bleeding and dysmenorrhea.
Contraindications: Pelvic inflammatory disease (PID).

Tocolytics

Purpose: Used to delay preterm labor.
Examples:
- Terbutaline - β2 agonist.
- Nifedipine - Ca2+ channel blocker.
- Indomethacin - NSAID.

Partial Androgen Receptor Agonists

Indications: Treat hereditary angioedema and endometriosis.
Side Effects: Idiopathic intracranial hypertension, decreased HDL levels, masculinization, hepatotoxicity, weight gain, hirsutism, edema, and acne.
Example: Danazol.

Full Androgen Receptor Agonists

Indications: Promote development of secondary sexual characteristics and treat hypogonadism.
Side Effects: Increased LDL and decreased HDL levels, testicular hypertrophy, and virilization in females.

Androgen Receptor Antagonists

Clinical Use: Treat prostate cancer and benign prostatic hyperplasia (BPH).
Examples:
- Abiraterone - used for prostate cancer.
- Finasteride - used for BPH, can cause hypertension, and sexual dysfunction.
- Flutamide and Bicalutamide - used for various cancers, with potential side effects like nausea and vomiting.

Gonadotropin-Releasing Hormone (GnRH) Antagonist

Usage: Primarily for prostate cancer treatment.
Side Effects: Hot flushes and potential liver toxicity.
Example: Degarelix.

Synthetic Estrogens

Indications: Hormone Replacement Therapy (HRT) for postmenopausal women.
Side Effects: Increased risk of clear cell adenocarcinoma of the vagina, particularly in women exposed to diethylstilbestrol (DES) in utero.
Contraindications: Tobacco use in females over 35 years old.### Bicalutamide
Indicated for prostate cancer treatment.
Associated side effect: gynecomastia.

Ketoconazole

Used in the management of prostate cancer.
Known side effects include sexual dysfunction.

Spironolactone

Utilized for conditions such as polycystic ovarian syndrome (PCOS).
Side effects include gynecomastia and amenorrhea.

Tamsulosin

Mechanism of action primarily targets benign prostatic hyperplasia (BPH).
Facilitates urination by relaxing prostate and bladder neck muscles.

Minoxidil

Primarily treats androgenic alopecia to promote hair growth.
Used for severe refractory hypertension, acting as a potent vasodilator.

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Description

This quiz explores the relationship between contraception and cancer. It covers various contraceptive methods and their potential links to different types of cancer. Test your knowledge on how contraception can impact health outcomes related to cancer.