Podcast
Questions and Answers
Which class of progestins do norethindrone and norethindrone acetate belong to?
Which class of progestins do norethindrone and norethindrone acetate belong to?
- Estranes (correct)
- Gonanes
- Dienogest
- Antiandrogenic progestins
Which progestin in the estranes category is mentioned to have more estrogenic activity compared to other progestins in the same class?
Which progestin in the estranes category is mentioned to have more estrogenic activity compared to other progestins in the same class?
- Ethynodiol diacetate (correct)
- Norgestrel
- Norethindrone
- Levonorgestrel
What is the class of progestins that include norgestrel and levonorgestrel?
What is the class of progestins that include norgestrel and levonorgestrel?
- Estranes
- Antiandrogenic progestins
- Dienogest
- Gonanes (correct)
Drospirenone is related to which other compound mentioned above?
Drospirenone is related to which other compound mentioned above?
Which compound derived from drospirenone is mentioned as having antiandrogenic activity?
Which compound derived from drospirenone is mentioned as having antiandrogenic activity?
In monophasic COCs, drospirenone is estimated to have an antiandrogenic activity equivalent to how much spironolactone?
In monophasic COCs, drospirenone is estimated to have an antiandrogenic activity equivalent to how much spironolactone?
Which type of cancer is NOT associated with reduced risk with COC use?
Which type of cancer is NOT associated with reduced risk with COC use?
What is the likely risk factor for chlamydia infections in women using COCs?
What is the likely risk factor for chlamydia infections in women using COCs?
Which of the following STIs is NOT associated with COC use?
Which of the following STIs is NOT associated with COC use?
What is the impact of COC use on pelvic inflammatory disease (PID)?
What is the impact of COC use on pelvic inflammatory disease (PID)?
Which of the following is a potential benefit of COC use?
Which of the following is a potential benefit of COC use?
What is the correlation between COC use and bacterial vaginosis?
What is the correlation between COC use and bacterial vaginosis?
Which generation of progestins used in combined oral contraceptive pills includes Norethindrone acetate?
Which generation of progestins used in combined oral contraceptive pills includes Norethindrone acetate?
Which progestin, listed in the text, has a distinct classification from others?
Which progestin, listed in the text, has a distinct classification from others?
Which one of these progestins is NOT classified under the second generation?
Which one of these progestins is NOT classified under the second generation?
Which progestin belongs to the first generation but NOT to the second generation?
Which progestin belongs to the first generation but NOT to the second generation?
According to the information, which generation of progestins includes Gestodene?
According to the information, which generation of progestins includes Gestodene?
Under what circumstances can a provider be reasonably certain that a patient is not pregnant?
Under what circumstances can a provider be reasonably certain that a patient is not pregnant?
What is the typical timeframe for a patient to return for the contraceptive implant after receiving a single injection of DMPA?
What is the typical timeframe for a patient to return for the contraceptive implant after receiving a single injection of DMPA?
What is the primary reason for offering a single injection of DMPA before the contraceptive implant?
What is the primary reason for offering a single injection of DMPA before the contraceptive implant?
According to the Quick Start Algorithm for Hormonal Contraception, what is an indication that a patient is not pregnant?
According to the Quick Start Algorithm for Hormonal Contraception, what is an indication that a patient is not pregnant?
What is a reliable method of contraception, according to the text?
What is a reliable method of contraception, according to the text?
What is the purpose of the checklist used to assess the possibility of pregnancy?
What is the purpose of the checklist used to assess the possibility of pregnancy?
What additional contraception is required if two or more consecutive hormonal pills are missed?
What additional contraception is required if two or more consecutive hormonal pills are missed?
What happens to the risk of ovulation if two or more pills are missed?
What happens to the risk of ovulation if two or more pills are missed?
When should emergency contraception be used if pills were missed in the first week of the cycle?
When should emergency contraception be used if pills were missed in the first week of the cycle?
What happens if pills were missed in the last week of hormone pills?
What happens if pills were missed in the last week of hormone pills?
Which of the following statements is true regarding the use of progestin-containing contraceptives at the same time as ulipristal acetate?
Which of the following statements is true regarding the use of progestin-containing contraceptives at the same time as ulipristal acetate?
What happens if one pill is missed?
What happens if one pill is missed?
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Study Notes
Quick Start Algorithm for Hormonal Contraception
- Providers may offer a single injection of DMPA and ask the patient to return for the implant within 5 days of the first day of her next menstrual period to avoid the need for implant removal if the repeat urine pregnancy test is positive.
Pregnancy Assessment
- A provider can be reasonably certain that a patient is not pregnant if she has no symptoms or signs of pregnancy and meets any of the following criteria:
- Has not had intercourse since last normal menses.
- Has been correctly and consistently using a reliable method of contraception.
- Is within 7 days from the first day of menstrual bleeding.
Contraceptives and Cancer
- COC use is associated with a slightly increased risk of developing cervical cancer.
- COC use is associated with a reduced risk of developing ovarian and endometrial cancers.
Contraceptives and STI Acquisition
- COC use positively correlates with chlamydia infections but not with gonorrhea, herpes simplex virus-2, trichomoniasis, syphilis, and human papillomavirus.
- COCs may be associated with increased rates of chlamydia, but not with pelvic inflammatory disease (PID).
Missed Pills
- If one pill is missed, the patient can take the missed pill as soon as possible and continue with the usual regimen.
- If two or more pills are missed, the remaining pills should be taken at the usual time, and backup contraception is generally needed.
- If two or more pills are missed in the first week of the cycle and unprotected intercourse occurs, use of emergency contraception may be necessary.
Progestins
- There are different classes of progestins, including estranes (e.g. norethindrone, norethindrone acetate), gonanes (e.g. norgestrel, levonorgestrel), and antiandrogenic progestins (e.g. drospirenone, dienogest, cyproterone acetate).
- Antiandrogenic progestins have some antiandrogenic activity and are sometimes referred to as fourth-generation progestins.
- Drospirenone is a weak antiandrogen that has progestogenic, antiandrogenic, and anti-mineralocorticoid activity.
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