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Calcium Channel Blockers: Dihydropyridines
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Calcium Channel Blockers: Dihydropyridines

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Questions and Answers

What is the primary mechanism of action of dihydropyridine calcium channel blockers?

  • Inhibits calcium leading to vascular smooth muscle relaxation (correct)
  • Enhances heart rate and cardiac output
  • Causes vasoconstriction by blocking vasodilation
  • Increases contractility of cardiac muscle
  • Which adverse effect is most commonly associated with dihydropyridine calcium channel blockers?

  • Bradycardia
  • Edema (correct)
  • Heart block
  • Tachycardia
  • In which population are dihydropyridine calcium channel blockers often used as a first line treatment for hypertension?

  • Elderly women
  • Caucasian adults
  • African Americans (correct)
  • Hispanic children
  • Which of the following statements about dihydropyridine calcium channel blockers is accurate?

    <p>They have no effect on heart rate.</p> Signup and view all the answers

    Which drug is a dihydropyridine calcium channel blocker?

    <p>Amlodipine</p> Signup and view all the answers

    Study Notes

    Calcium Channel Blockers (CCB) - Dihydropyridines

    • Amlodipine (Norvasc) and Nicardipine (Cardene) are dihydropyridine calcium channel blockers.
    • They inhibit calcium influx, leading to relaxation of vascular smooth muscle and vasodilation.
    • Key indication: Hypertension.
    • Common adverse effects: Edema, orthostatic hypotension.
    • Typically considered first-line treatment for hypertension in African Americans.
    • Dihydropyridines are a subclass of calcium channel blockers.
    • These drugs do not affect heart rate.

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    Description

    This quiz focuses on dihydropyridine calcium channel blockers, specifically Amlodipine and Nicardipine. It covers their mechanism of action, indications, adverse effects, and their role in treating hypertension, particularly in African Americans. Test your knowledge on these important medications and their effects!

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