Skeletal Muscle Calcium Ion Flux

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What is the main function of skeletal muscle in relation to the skeleton?

To move bones of the skeleton at joints

What is the functional unit of the skeletal muscle?

Sarcomere

What is the role of troponin in muscle contraction?

To bind to calcium and expose actin binding site for myosin

What is the outcome of thin filaments sliding along thick filaments during muscle contraction?

The I bands disappear and the A bands remain constant

What is the role of myosin in muscle contraction?

To have ATPase activity and move along the thin filaments

What is the site of binding for myosin on the thin filaments?

Actin

What is the role of calcium in muscle contraction?

To bind to troponin-C and expose actin binding site for myosin

What is the structural protein of the thin filaments?

Actin

What is the result of the troponin-tropomyosin complex moving during muscle contraction?

The actin binding site for myosin is exposed

What is the composition of troponin?

Three subunits: troponin-T, troponin-I, and troponin-C

This quiz covers the electrochemical gradient of calcium ions in skeletal muscle cells, including the role of dihydropyridine and ryanodine receptors in regulating calcium ion flux from the sarcoplasmic reticulum to the cytosol.

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