C. Difficile Infection and Pseudomembranous Colitis
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Questions and Answers

Pseudomembranous colitis is a severe and sometimes fatal form of ______ that results from the overgrowth of C.difficile in the colon.

colitis

The causative organism, C.difficile, produces and releases potent ______ that induce colitis and diarrhea.

enterotoxins

Pseudomembranous colitis is the most common ______ infection of the GI tract.

nosocomial

C.difficile is a ______ positive, spore-forming anaerobic rod that has been found in sand, soil, and feces.

<p>gram</p> Signup and view all the answers

C.difficile colonizes the gut in ______ to 3% of asymptomatic adults and up to 50% of older adults.

<p>2%</p> Signup and view all the answers

The risk of disease increases in areas where ______ are inhaled and when broad-spectrum antibiotics are in prolonged use.

<p>spores</p> Signup and view all the answers

Flashcards

Pseudomembranous colitis

A severe form of colitis caused by an overgrowth of C. difficile in the colon.

C. difficile enterotoxins

Powerful toxins produced by C. difficile that cause inflammation and diarrhea.

Nosocomial infection

An infection acquired in a hospital or healthcare setting.

C. difficile characteristics

C. difficile is a Gram-positive, spore-forming, anaerobic rod found in the environment.

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C. difficile asymptomatic colonization

C. difficile may colonize the gut in a small percentage of adults without causing any symptoms.

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Risk factors for C. difficile infection

Risk increases with inhaling spores, prolonged use of broad-spectrum antibiotics, and potentially in older adults.

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