Pseudomembranous Colitis: Causes and Pathogenesis

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Questions and Answers

What is the primary cause of pseudomembranous colitis?

  • Prolonged use of broad-spectrum antibiotics
  • Loss of anaerobic gut bacteria (correct)
  • Inhalation of spores in hospitals
  • Overgrowth of C.difficile in the colon

What is the most common population affected by pseudomembranous colitis?

  • Patients in hospitals and nursing homes
  • Older adults (correct)
  • Infants and young children
  • Patients with suppressed immune systems

What is the percentage of asymptomatic adults who have C.difficile in their gut?

  • 1% to 2%
  • 2% to 3% (correct)
  • 5% to 10%
  • 10% to 20%

What is the purpose of C.difficile in pseudomembranous colitis?

<p>To produce potent enterotoxins (A)</p> Signup and view all the answers

What is the result of the overgrowth of C.difficile in the colon?

<p>Severe and sometimes fatal form of colitis (A)</p> Signup and view all the answers

What is the characteristic of C.difficile spores?

<p>They are relatively resistant to many disinfectants (C)</p> Signup and view all the answers

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