Podcast
Questions and Answers
In human pedigrees, which characteristic indicates autosomal dominant inheritance?
In human pedigrees, which characteristic indicates autosomal dominant inheritance?
- Males and females are equally likely to be affected (correct)
- The trait typically appears only within a sibship, not in other generations
- The recurrence risk for each sib of the proband is 25%
- New mutations are relatively common
What characteristic of recessive traits in pedigrees makes them difficult to recognize?
What characteristic of recessive traits in pedigrees makes them difficult to recognize?
- Affected individuals can be the children of two unaffected carriers (correct)
- Affected children always have at least one affected parent
- Two affected parents can produce unaffected children
- Vertical pattern of inheritance
Why is Huntington’s disease inherited as a dominant allele?
Why is Huntington’s disease inherited as a dominant allele?
- If it appears in more than one family member, typically it is seen only within a sibship, not in other generations
- Every affected person has at least one affected parent (correct)
- Each child of an affected parent has a 50% risk of inheriting the trait
- Parents of affected individuals are unaffected but are heterozygous for the recessive allele
What is a key aspect of pedigrees with dominant traits?
What is a key aspect of pedigrees with dominant traits?
What characteristic distinguishes autosomal dominant inheritance from autosomal recessive inheritance?
What characteristic distinguishes autosomal dominant inheritance from autosomal recessive inheritance?
What is the molecular explanation for the shape of wrinkled peas in Mendel's experiment?
What is the molecular explanation for the shape of wrinkled peas in Mendel's experiment?
What is the molecular explanation for the color of green peas in Mendel's experiment?
What is the molecular explanation for the color of green peas in Mendel's experiment?
Which enzyme is responsible for breaking down chlorophyll in peas?
Which enzyme is responsible for breaking down chlorophyll in peas?
What happens when a recessive allele is present according to one of the general molecular principles mentioned?
What happens when a recessive allele is present according to one of the general molecular principles mentioned?
What is the effect of the R allele in Mendel's experiment?
What is the effect of the R allele in Mendel's experiment?
