Molecular Genetics: Mendel's Pea Shape Explanation
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Questions and Answers

Which disease exhibits a dominant pattern of inheritance based on the pedigree analysis?

  • Huntington’s disease (correct)
  • Sickle cell anemia
  • Tay-Sachs disease
  • Cystic fibrosis
  • Which disease exhibits a recessive pattern of inheritance based on the pedigree analysis?

  • Marfan syndrome
  • Cystic fibrosis (correct)
  • Familial hypercholesterolemia
  • Neurofibromatosis type I
  • What is a key aspect of pedigrees with dominant traits?

  • Affected children always have at least one affected parent (correct)
  • Dominant traits show a horizontal pattern of inheritance
  • Dominant traits only affect males
  • Two affected parents never produce unaffected children
  • Which single-gene trait caused by a dominant allele has the highest frequency among humans?

    <p>Familial hypercholesterolemia</p> Signup and view all the answers

    What is the likelihood of an unaffected family member transmitting the phenotype to their children in autosomal dominant inheritance?

    <p>Unaffected family members do not transmit the phenotype to their children.</p> Signup and view all the answers

    What is a characteristic of diseases with recessive alleles in humans?

    <p>They often require both parents to be carriers in order for the offspring to be affected.</p> Signup and view all the answers

    What is the molecular explanation for the wrinkled peas in Mendel's pea shape experiment?

    <p>The R allele encodes Starch branching enzyme (Sbe1) and the r allele does not make Sbe1, leading to sucrose and unbranched starch build-up.</p> Signup and view all the answers

    What is the molecular explanation for the green peas in Mendel's pea color experiment?

    <p>The Y allele encodes Stay green enzyme (Sgr) and the y allele does not make Sgr, leading to chlorophyll not being broken down and the peas remaining green.</p> Signup and view all the answers

    Based on the general molecular principles, what does a dominant allele usually determine?

    <p>A normally functioning protein</p> Signup and view all the answers

    According to the general molecular principles, what does a recessive allele usually encode?

    <p>A non-functional protein</p> Signup and view all the answers

    What happens when the y allele is present in Mendel's pea color experiment?

    <p>Chlorophyll is not broken down and the peas remain green</p> Signup and view all the answers

    What is the consequence of having the r allele in Mendel's pea shape experiment?

    <p>Sucrose and unbranched starch build up, leading to wrinkled peas</p> Signup and view all the answers

    What is the molecular explanation for the wrinkled peas in Mendel's experiment?

    <p>The R allele encodes Starch branching enzyme (Sbe1), while the r allele does not make Sbe1, leading to build-up of sucrose and unbranched starch, causing wrinkled peas</p> Signup and view all the answers

    What is the role of the Y allele in determining pea color in Mendel's experiment?

    <p>The Y allele encodes the Stay green enzyme (Sgr), which helps break down chlorophyll, resulting in green peas</p> Signup and view all the answers

    Based on the general molecular principles mentioned, what does a dominant allele usually determine?

    <p>A normally functioning protein</p> Signup and view all the answers

    According to the general molecular principles mentioned, what does a recessive allele usually encode?

    <p>A non-functional protein</p> Signup and view all the answers

    What happens when the r allele is present in Mendel's experiment?

    <p>Sucrose and unbranched starch build up, leading to wrinkled peas</p> Signup and view all the answers

    What is the effect of the Y allele in Mendel's experiment?

    <p>Chlorophyll breakdown, resulting in green peas</p> Signup and view all the answers

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