Blood Transfusion ABO Incompatibility

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29 Questions

What is the purpose of washing red blood cells with a series of saline solutions with decreasing osmolality?

To remove glycerol from the red cells

What is the primary indication for using washed red blood cells?

Patients with anaphylactic reactions to plasma proteins

What is the primary purpose of irradiating red blood cells?

To prevent transfusion-associated graft vs.host disease

What is a disadvantage of using washed red blood cells?

It is an open system

What is the expected loss of red cells during the washing process?

10-20% of the total volume

What is the storage temperature for washed red blood cells?

1-6°C

What is a common sign of a transfusion reaction?

Jaundice

What type of antibody is involved in delayed hemolytic transfusion reactions?

IgG

What should be done immediately when a patient shows signs of a transfusion reaction?

Stop the transfusion

What is the primary mechanism involved in immune-mediated hemolytic transfusion reactions?

Complement activation

What is the typical time frame for acute hemolytic transfusion reactions?

Within 24 hours

What is the primary objective of rechecking the patient and blood unit ABO group?

To ensure ABO compatibility

What information is included on the labeling form/tag attached to the donor unit?

Patient's full name, ID number, ABO/Rh, donor number, and compatibility results

What is the most common contaminant found in blood bags?

Yersinia enterocolitica

What is the purpose of visually inspecting the blood unit before release?

To detect bacterial contamination or clots

What is the process of releasing a blood product to the nurse or physician?

Comparing the requisition form, donor unit tag, and blood product label

What should be done if the blood unit is unused?

Return it to the inventory

What is the minimum time a nurse must stay with the patient after the infusion of blood?

15 minutes

What is the purpose of using a filter during blood transfusion?

To remove gross blood clots and cellular debris

Why is it essential to infuse blood within 4 hours of its release from the blood bank facility?

To prevent bacterial contamination

What is the purpose of documenting the blood transfusion process?

To verify consent and track any transfusion reactions

What is the standard size of the filter used to remove cellular and plasma components from the blood?

170-260 micrometers

What is the consequence of infusing blood with 5% dextrose?

Hemolysis in vivo

What is the primary cause of Transfusion-Associated Graft Vs Host Disease?

Immunocompetent donor lymphocytes

Which of the following is a major complication of Transfusion-Associated Graft Vs Host Disease?

Sepsis and hemorrhage

What is the primary method of prevention for Transfusion-Associated Graft Vs Host Disease?

Irradiation of blood products before transfusion

What is the primary cause of Bacterial Contamination of Blood Products?

Improper cleansing during collection

What is the primary complication of Transfusion-Associated Circulatory Overload?

Chronic Heart Failure

What is the primary prevention method for Citrate Toxicity?

Remove-plasma

This quiz covers the steps to take when dealing with ABO incompatibility in blood transfusions, including rechecking patient and blood unit ABO groups and checking for clinically significant antibodies.

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