Blood Transfusion ABO Incompatibility

Play an AI-generated podcast conversation about this lesson

What is the purpose of washing red blood cells with a series of saline solutions with decreasing osmolality?

To remove glycerol from the red cells (correct)

To remove leukocytes from the blood

To remove plasma proteins from the red cells

To remove residual plasma IgA from the blood

What is the primary indication for using washed red blood cells?

Patients with immunodeficiency disorders

Patients with leukemia

Patients with sickle cell anemia

Patients with anaphylactic reactions to plasma proteins (correct)

What is the primary purpose of irradiating red blood cells?

To prevent transfusion-associated graft vs.host disease (correct)

To remove leukocytes from the blood

To inactivate viral pathogens in the blood

To prevent the transmission of blood-borne pathogens

What is a disadvantage of using washed red blood cells?

It is an open system Signup and view all the answers

What is the expected loss of red cells during the washing process?

10-20% of the total volume Signup and view all the answers

What is the storage temperature for washed red blood cells?

1-6°C Signup and view all the answers

What is a common sign of a transfusion reaction?

Jaundice Signup and view all the answers

What type of antibody is involved in delayed hemolytic transfusion reactions?

IgG Signup and view all the answers

What should be done immediately when a patient shows signs of a transfusion reaction?

Stop the transfusion Signup and view all the answers

What is the primary mechanism involved in immune-mediated hemolytic transfusion reactions?

Complement activation Signup and view all the answers

What is the typical time frame for acute hemolytic transfusion reactions?

Within 24 hours Signup and view all the answers

What is the primary objective of rechecking the patient and blood unit ABO group?

To ensure ABO compatibility Signup and view all the answers

What information is included on the labeling form/tag attached to the donor unit?

Patient's full name, ID number, ABO/Rh, donor number, and compatibility results Signup and view all the answers

What is the most common contaminant found in blood bags?

Yersinia enterocolitica Signup and view all the answers

What is the purpose of visually inspecting the blood unit before release?

To detect bacterial contamination or clots Signup and view all the answers

What is the process of releasing a blood product to the nurse or physician?

Comparing the requisition form, donor unit tag, and blood product label Signup and view all the answers

What should be done if the blood unit is unused?

Return it to the inventory Signup and view all the answers

What is the minimum time a nurse must stay with the patient after the infusion of blood?

15 minutes Signup and view all the answers

What is the purpose of using a filter during blood transfusion?

To remove gross blood clots and cellular debris Signup and view all the answers

Why is it essential to infuse blood within 4 hours of its release from the blood bank facility?

To prevent bacterial contamination Signup and view all the answers

What is the purpose of documenting the blood transfusion process?

To verify consent and track any transfusion reactions Signup and view all the answers

What is the standard size of the filter used to remove cellular and plasma components from the blood?

170-260 micrometers Signup and view all the answers

What is the consequence of infusing blood with 5% dextrose?

Hemolysis in vivo Signup and view all the answers

What is the primary cause of Transfusion-Associated Graft Vs Host Disease?

Immunocompetent donor lymphocytes Signup and view all the answers

Which of the following is a major complication of Transfusion-Associated Graft Vs Host Disease?

Sepsis and hemorrhage Signup and view all the answers

What is the primary method of prevention for Transfusion-Associated Graft Vs Host Disease?

Irradiation of blood products before transfusion Signup and view all the answers

What is the primary cause of Bacterial Contamination of Blood Products?

Improper cleansing during collection Signup and view all the answers

What is the primary complication of Transfusion-Associated Circulatory Overload?

Chronic Heart Failure Signup and view all the answers

What is the primary prevention method for Citrate Toxicity?

Remove-plasma Signup and view all the answers