Questions and Answers
What is one of the primary functions of blood?
Blood helps maintain normal pH levels in the body.
True
What are the three main cellular elements of blood?
Erythrocytes, leukocytes, thrombocytes
Blood prevents infection by carrying __________, which are vital for immune response.
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Match the function of blood with its description:
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Erythropoietin (EPO) is primarily produced in which organ?
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Platelets are responsible for transporting oxygen in the blood.
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What role do plasma proteins play in blood?
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What is the main function of hemoglobin (Hb) in erythrocytes?
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Erythropoietin (EPO) is released by the heart in response to low oxygen levels.
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What is the approximate number of red blood cells (RBCs) produced per second?
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The process of formation of RBCs is called __________.
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What color does oxyhemoglobin appear?
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Match the following components with their associated functions:
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A high number of red blood cells in the blood decreases blood viscosity.
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What is one dietary requirement for erythropoiesis?
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What blood type is considered the universal donor?
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A patient with type AB blood can receive blood from any blood type without risk of transfusion reactions.
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What causes transfusion reactions when mismatched blood is infused?
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Type A blood has the _____ agglutinogen on its red blood cells.
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Which of the following statements regarding blood type inheritance is correct?
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Match the following blood types with their characteristics:
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The presence of anti-A antibodies in the plasma would enable a person with type B blood to receive type AB blood safely.
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What are the small blood vessels that can become clogged during a transfusion reaction?
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What is a possible negative consequence of abusing erythropoietin (EPO) by athletes?
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All leukocytes, or white blood cells, contain visible cytoplasmic granules.
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What hormone is released by the kidneys to stimulate red bone marrow in the production of red blood cells?
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Leukocytosis is defined as a WBC count over _____ per µl.
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Match the following types of leukocytes with their characteristics:
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What can cause hemoglobin levels to decrease?
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The primary function of leukocytes is to aid in oxygen transport in the blood.
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What happens to hematocrit levels when EPO is misused by athletes?
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A patient with blood type O can receive blood from which of the following types?
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Anti-Rh antibodies are spontaneously formed in Rh- individuals.
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What is erythroblastosis fetalis?
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RhoGAM serum is used to prevent Rh- mothers from becoming __________.
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Match the blood tests with their descriptions:
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What factor indicates the presence of the D antigen in a person's blood?
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First pregnancy of an Rh- mother with an Rh+ fetus poses risks of hemolytic disease.
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What is the most common Rh factor among the named Rh agglutinogens?
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Study Notes
Functions of Blood
- Blood serves as the primary transport medium in the cardiovascular system, facilitating vital physiological functions.
- Major functions include:
- Transport: Delivers oxygen and nutrients to cells, removes metabolic wastes, and transports hormones from endocrine glands to target organs.
- Regulation: Helps maintain body temperature, normal pH levels via buffers, and fluid volume in the circulatory system.
- Protection: Prevents blood loss through clot formation and helps defend against infections with immune agents like antibodies and white blood cells.
Cellular Components of Blood
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Blood consists of cellular elements and the extracellular matrix known as plasma.
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Erythrocytes (Red Blood Cells):
- Contain hemoglobin (Hb), capable of transporting up to four molecules of oxygen.
- Approximately 250 million Hb molecules present in each RBC.
- Functions include oxygen loading in lungs (forming oxyhemoglobin) and unloading in tissues (forming deoxyhemoglobin).
- Carbon dioxide binding occurs in tissues, with 20% of CO2 binding to Hb forming carbaminohemoglobin.
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Leukocytes (White Blood Cells):
- Complete cells with nuclei and organelles, crucial for immune defense.
- Classified into granulocytes (with visible granules) and agranulocytes (without visible granules).
- Leukocytosis refers to a WBC count exceeding 11,000 cells per microliter, commonly a response to infection.
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Thrombocytes (Platelets):
- Key players in clot formation, aiding in the prevention of blood loss.
Erythropoiesis and Erythropoietin (EPO)
- Erythropoiesis: The formation of RBCs that takes approximately 15 days.
- Critical factors include:
- Hormonal controls, specifically erythropoietin (EPO), released by kidneys (and some from the liver), which increases RBC production in response to hypoxia.
- Dietary requirements impact RBC production; deficiencies (e.g., iron) can hinder hemoglobin synthesis.
Blood Typing and Transfusion Reactions
- Human blood types include ABO (A, B, AB, O) and Rh factor (positive or negative).
- Blood type is inherited; A and B are dominant, while O is recessive.
- Mismatched transfusion can provoke severe immune responses leading to agglutination and potential life-threatening complications.
- Type O is considered a universal donor, while type AB is a universal recipient due to the absence of anti-A and anti-B antibodies.
Rh Factor Implications
- 52 named Rh antigens, with D being the most significant.
- Rh positive indicates D antigen presence.
- Anti-Rh antibodies do not occur spontaneously in Rh-negative individuals but develop upon exposure to Rh-positive blood.
- Hemolytic disease of the newborn can occur when an Rh-negative mother has an Rh-positive fetus, requiring preventative measures like RhoGAM serum.
Diagnostic Blood Tests
- Blood analysis provides insights into overall health:
- Low hematocrit levels may indicate anemia.
- Blood glucose tests are utilized for diabetes screening.
- High leukocyte counts may suggest infection.
- Microscopic examination can reveal abnormalities in RBC size or shape, which are indicative of various health conditions.
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Description
This quiz covers the various functions of blood, including its role in transport and immune response. It also examines the cellular elements and extracellular matrix of blood, focusing on erythrocytes, leukocytes, and thrombocytes. Test your understanding of these critical components of the circulatory system.