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Blood Components: Reentry into Vasculature

Explore how plasma and all the formed elements of blood reenter the vasculature, passing through narrow slits between stave cells into sinusoids. Learn about the selective removal of stiff or effete, swollen red blood cells by macrophages.

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@UnfetteredPsaltery
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Questions and Answers

Where do defective red blood cells undergo selective removal by macrophages?

Red pulp

Which of the following is a major function of the red pulp in the spleen?

Iron storage and recycling

What happens to iron released from hemoglobin during RBC degradation?

Stored by macrophages in the red pulp

After splenectomy, where do most abnormal erythrocytes get removed by macrophages?

<p>Liver sinusoids</p> Signup and view all the answers

What is the fate of iron-free heme in the spleen?

<p>Bound to hemopexin or excreted in bile</p> Signup and view all the answers

Which structure lacks significant smooth muscle and forms the splenic vein?

<p>Trabecular veins</p> Signup and view all the answers

What is the main function of the endothelial stave cells that line the sinusoids in the red pulp of the spleen?

<p>Filtering out effete erythrocytes</p> Signup and view all the answers

Which component of the splenic sinusoids is highly discontinuous and allows for the passage of blood cells?

<p>Basement membrane</p> Signup and view all the answers

In the spleen's open circulation mode, what happens to blood cells that cannot move between the stave cells in the splenic cords?

<p>They are engulfed by macrophages</p> Signup and view all the answers

Which structure in the spleen resembles a loosely organized wooden barrel, as depicted in a diagram?

<p>Endothelial stave cells</p> Signup and view all the answers

What is the main role of T lymphoblasts in the thymus, according to the text?

<p>Attaching to cytoreticulum composed of thymic epithelial cells</p> Signup and view all the answers

What is the key role of thymic epithelial cells (TECs) in the thymus, as mentioned in the text?

<p>Surrounding blood vessels in the blood-thymus barrier</p> Signup and view all the answers

What is the role of splenic cords in the red pulp?

<p>Contain a network of reticular cells and fibers filled with T and B lymphocytes</p> Signup and view all the answers

What characterizes the endothelial cells in the splenic sinusoids?

<p>Elongated and sparsely wrapped in reticular fibers</p> Signup and view all the answers

What is the function of the splenic sinusoids in the red pulp?

<p>Provide additional immune surveillance of blood</p> Signup and view all the answers

In the closed circulation through the splenic red pulp, what happens to the blood flow?

<p>Blood is always enclosed by endothelium</p> Signup and view all the answers

How are the splenic cords and splenic sinusoids arranged in the red pulp?

<p>Cords contain reticular cells and fibers filled with lymphocytes, separated by sinusoids</p> Signup and view all the answers

What distinguishes the open circulation in the splenic red pulp?

<p>Capillaries empty blood into stroma of splenic cords</p> Signup and view all the answers

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