Biopsychology Session 2 Lectures 5-7
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Questions and Answers

What cell sends inhibitory signals?

  • Horizontal cell (correct)
  • Ganglion cell
  • Photoreceptor
  • Bipolar cell
  • What is the main source of colour vision?

  • Rods in the retina
  • Cones in the retina
  • Cones in the fovea (correct)
  • Rods in the fovea
  • When is the visual system developed?

  • Trichromatic theory
  • Opponent process theory
  • Retinex theory (correct)
  • Astigmatism theory
  • What color theory can explain an afterimage?

    <p>Opponent process theory</p> Signup and view all the answers

    When trying to infer how you can move around, you use the __ stream that sends information to the __ lobe.

    <p>dorsal, parietal</p> Signup and view all the answers

    Why is the fovea specialized in details?

    <p>Each photoreceptor is connected to one bipolar cell which is connected to a single midget ganglion cell.</p> Signup and view all the answers

    What is the blind spot and why do we not notice it?

    <p>The blind spot is where the optic nerve leaves the retina. We do not notice it because our brain compensates for it with the other eye.</p> Signup and view all the answers

    Is vision contralateral, like how your left hand is connected to your right hemisphere?

    <p>Both</p> Signup and view all the answers

    What are the two types of photoreceptors?

    <p>Rods and Cones</p> Signup and view all the answers

    What causes colour vision deficiency?

    <p>Impairment in seeing colours</p> Signup and view all the answers

    Damage to the Ventral Stream can cause visual agnosia.

    <p>True</p> Signup and view all the answers

    What theory of pitch perception is correct?

    <p>None, a combination is required to fully explain it</p> Signup and view all the answers

    How does the vestibular system help with balance?

    <p>The vestibular system helps with balance by detecting every movement due to fluid and moving the hair cells.</p> Signup and view all the answers

    What is the dermatome?

    <p>Spinal nerves that send info from periphery to brain</p> Signup and view all the answers

    The vomeronasal organ contains receptors that detect:

    <p>Only pheromones</p> Signup and view all the answers

    What statement is incorrect?

    <p>Golgi tendon organs are located parallel to a muscle</p> Signup and view all the answers

    Which motor cortex is similar in function to the prefrontal cortex?

    <p>Supplementary motor cortex</p> Signup and view all the answers

    A patient has an overly active thalamus. Is it more likely that the person has Parkinson's or Huntington's disease? Why?

    <p>The person is more likely to have Huntington's disease. In Huntington's disease, damage in the basal ganglia increases thalamus activity.</p> Signup and view all the answers

    What is not true about the cerebellum?

    <p>It has more neurons than in the rest of the entire brain</p> Signup and view all the answers

    Autoreceptors are located on the _______

    <p>presynaptic membrane</p> Signup and view all the answers

    Which of the following is true of Oligodendrocytes and Schwann cells?

    <p>Schwann cells provide myelin for nerve cells</p> Signup and view all the answers

    What is required for the control group when performing a lesion?

    <p>Sham lesion</p> Signup and view all the answers

    Neurotransmitters are secreted from the

    <p>Axon terminal</p> Signup and view all the answers

    Hyperpolarization is _____ because of how slow ____ is

    <p>potential becoming overly negative, K+</p> Signup and view all the answers

    What is an advantage of myelination?

    <p>Myelin allows for quick and efficient transmission of action potential</p> Signup and view all the answers

    What happens if a stimulus reaches -60 mV?

    <p>fast firing action potential</p> Signup and view all the answers

    Match up the correct receptor type and effect

    <p>a. ionotropic = more time required to open an ion channel b. metabotropic = G protein activations leads to activation of a second messenger c. metabotropic = short-lived effect on ion channels d. metabotropic = direct opening of an ion channel</p> Signup and view all the answers

    Cerebrospinal fluid is produced within ____

    <p>ventricles</p> Signup and view all the answers

    The basal ganglia does not consist of

    <p>amygdala</p> Signup and view all the answers

    What procedure uses magnetic waves to alter brain neural activity?

    <p>transcranial magnetic stimulation</p> Signup and view all the answers

    What is a key advantage of a reversible lesion?

    <p>each animal can serve as its own control</p> Signup and view all the answers

    A unique feature of the fovea is that it

    <p>contains only cone photoreceptors</p> Signup and view all the answers

    The ventral visual stream projects to ____ and is involved in _____

    <p>temporal lobe, what an object is</p> Signup and view all the answers

    Put the parts of the auditory system in the correct order from where the sound enters

    <p>a. hair cells = 3 b. pinna = 1 c. auditory canal = 2 d. oval window &amp; cochlea = 4 e. stirrup, anvil and hammer = 5</p> Signup and view all the answers

    Study Notes

    Biopsychology: Vision

    • The process of vision involves:
      • Light entering through the pupil and being focused by the lens and cornea
      • Projection of light onto the retina
      • Recognition of different wavelengths by photoreceptors
      • Activation of bipolar and ganglion cells
      • Refinement of the image by amacrine cells and horizontal cells
    • The fovea is specialized for detail because each photoreceptor is connected to one bipolar cell, which is connected to a single midget ganglion cell
    • The blind spot is where the optic nerve leaves the retina, but it is compensated for by the other eye

    Photoreceptors

    • There are two types of photoreceptors: rods and cones
    • Rods are found throughout the retina, while cones are only found in the fovea
    • Both types of photoreceptors release photopigments when struck by light, modifying receptor sensitivity to different wavelengths

    Colour Vision

    • There are three theories of colour vision:
      • Trichromatic theory: colour is determined by comparing the response of three types of cones with different wavelength sensitivities
      • Opponent-process theory: colour is perceived in terms of opposites (e.g. blue-yellow, red-green, black-white)
      • Retinex theory: the ability to see colour despite changes in lighting, by comparing visual input with previously encountered information

    Anatomy of Visual Processing

    • The optic nerve pathway involves:
      • The optic nerve leaving the eye
      • The optic nerve crossing in the optic chiasm
      • The optic nerve traveling to the lateral geniculate nucleus (part of the thalamus)
      • The lateral geniculate nucleus sending information to the visual cortex

    Lateral Inhibition

    • Lateral inhibition allows for optimal object-background differentiation by:
      • Activating neighbouring neurons to heighten contrast
      • Inhibiting bipolar cells in the middle of the illuminated area
      • Allowing bipolar cells on the border to receive only a slight inhibitory signal

    Cells

    • There are several types of cells involved in visual processing, including:
      • Photoreceptors: activate bipolar and horizontal cells
      • Bipolar cells: activate ganglion cells
      • Ganglion cells: have a doughnut-shaped receptive field and respond to movement and large patterns
      • Parvocellular neurons: detect details and colour, found near the fovea
      • Magnocellular neurons: respond to movement and large patterns, found throughout the retina
      • Koniocellular neurons: have some colour sensitivity, found throughout the retina

    Development of Visual Cortex

    • The visual system develops before birth, but requires experience to develop, particularly:
      • Synchronizing activity of neighbouring receptors to form connections with cells
      • Visual-experience for fine-tuning
      • Retinal disparity (discrepancy between left and right eye) for stereoscopic depth perception

    Ventral and Dorsal Pathway

    • The ventral stream (what pathway) is involved in recognizing objects, while the dorsal stream (how pathway) guides movement with visual input
    • Damage to the ventral stream can cause visual agnosia (inability to recognize objects)

    Visual Hierarchy

    • The visual hierarchy involves:
      • Receptive fields becoming larger and more specialized
      • V1 (primary visual cortex): basic features (such as lines and edges)
      • V2 (secondary visual cortex): patterns
      • V3: colour
      • V4: recognition
      • V5 (middle temporal cortex): motion

    Object Recognition

    • Most brain areas do not respond more to one object than another, but exceptions include:
      • Parahippocampal cortex: responds more to pictures of places
      • Fusiform gyrus: responds more to faces, and damage in this area can cause prosopagnosia (face blindness)

    Mechanical and Chemical Senses

    • The auditory system involves:
      • Sound waves differing in amplitude, frequency, and timbre
      • Sound entering at the pinna and traveling through the auditory canal
      • Vibration of the oval window creating motion in the liquid in the cochlea
      • Recognition of different sounds by the auditory cortex### Pitch Perception
    • Theories of pitch perception:
      • Place theory: certain hair cells respond to specific frequencies, but limited as individual areas of the basilar membrane cannot vibrate on their own.
      • Frequency theory: the entire basilar membrane vibrates at the same frequency as the sound, but limited for low frequencies.
      • Volley principle: several neural populations fire simultaneously, but out of phase with each other.

    Auditory Cortex

    • 2 pathways of auditory processing:
      • Pathway to process identity: anterior temporal cortex (ventral stream).
      • Pathway to process location: posterior temporal cortex (dorsal stream).
    • Primary auditory cortex (A1): processes complex sounds.
    • A2: processes nature sounds.
    • Superior temporal cortex: processes motion and is responsible for motion deafness when damaged.

    Sound Localization

    • Methods for sound localization:
      • Difference in time of arrival.
      • Difference in intensity (shadow of the head).
      • Phase difference between the ears.

    Hearing Loss

    • Types of hearing loss:
      • Deafness: due to environmental factors (e.g., exposure to loud sounds).
      • Conductive deafness: middle ear unable to send soundwaves to cochlea, usually temporary, and treatable with surgery or implants.
      • Nerve deafness: damage to cochlea, hair cells, or auditory nerve, can be inherited or due to exposure.

    Vestibular System

    • Responsible for balance and distinguishing between self and external movement.
    • Semicircular canals filled with fluid and lined with hair cells.

    Somatosensation

    • Experience of touch, pressure, pain, itch, temperature, and movement.
    • Somatosensory receptors:
      • Pacinian corpuscles: detect vibration and sudden displacement on skin.
      • Merkel's disks: detect light touch.
      • Meissner's corpuscle: detect skin movement and object handling.
      • Ruffini ending: detect skin stretching, movement, and finger position.

    Awareness of Touch

    • Information in the CNS:
      • Info from the head to the brain via cranial nerves.
      • Touch info from periphery to brain via spinal nerves (dermatome).
    • Pain:
      • Same pathway as touch.
      • Starts from bare nerve endings in the skin.
      • Dull pain is slow due to unmyelinated axons.
      • Sharp pain is fast due to myelinated axons.

    Pain Relief

    • Mechanisms of pain relief:
      • Opioid mechanism: opiates and endorphins bind to receptors in the spinal cord and midbrain.
      • Gate theory: pain differs from time to time, and the body closes the 'gate' for pain with endorphins.
      • Anti-inflammatory drugs: reduce release of chemicals in damaged tissue.
      • Placebo: the mere expectation of pain relief.

    Taste

    • Taste receptors:
      • 50 receptors for 5 different tastes.
      • Located in papillae.
      • Combination of taste and smell (endopiriform cortex).
    • Experience:
      • Adaptation: reduction of taste due to fatigue of receptor.
      • Cross-adaptation: reduction in response to a different taste.
    • Taste coding in the brain:
      • Taste nerves go to the nucleus of the tractus solitarius (NTS) in the medulla.
      • To somatosensory cortex for touch.
      • To insula (primary taste cortex).

    Olfaction

    • Smell:
      • Olfactory cells line the epithelium.
      • Cilia (threadlike dendrites) and metabotropic effects.
      • Info sent to olfactory bulb.
      • Women generally have a better sense of smell.
    • Pheromones:
      • Unconsciously affect behavior.
      • Only respond to vomeronasal organ.
      • Synchronize menstrual cycles.

    Movement

    • Muscle contractions:
      • Muscle control by axon releasing acetylcholine.
      • In neuromuscular junction (synapse motor neuron).
    • Types of muscles:
      • Smooth muscles: digestive system.
      • Skeletal/striated muscles: movement of body.
      • Cardiac muscles: heart.
    • Aerobic or anaerobic:
      • Slow-twitch fibers: aerobic, do not fatigue, oxygen as energy source.
      • Fast-twitch fibers: anaerobic, create oxygen debt, ATP and glycogen as energy source.

    Muscle Proprioceptors

    • Proprioceptors:
      • Detects the stretch and tension of muscles.
      • Signals to spinal cord to adjust muscle.
      • Stretch reflex.
    • 2 types of proprioceptors:
      • Muscle spindles: located parallel to muscles, respond to stretch, and provide negative feedback.
      • Golgi tendon organs: located in tendons, respond to increase in tension, and inhibit further contraction to prevent damage.

    Motor Patterns

    • Reflex:
      • Consistent, automatic response to a stimuli.
      • Ballistic (once they occur, they cannot be stopped or corrected).
    • Sequential movements:
      • Central pattern generators: neural mechanisms of rhythmic patterns of movement.
      • Motor program: a fixed sequence of movements.

    Primary Motor Cortex

    • Orders movement outcome.
    • Posterior parietal cortex: monitors position of body in environment.
    • Supplementary motor cortex: planning, rapid sequence movements, and habits.
    • Prefrontal cortex: planning, habits, and stores relevant movement info.
    • Premotor cortex: active immediately before movement.

    Spinal Cord

    • Corticospinal tract: pathway from cerebral cortex to spinal cord.
    • Lateral corticospinal tract: axons from primary motor cortex and the red nucleus.
    • Medial corticospinal tract: axons from midbrain, tectum, and vestibular nucleus.

    Cerebellum

    • Balance, coordination, timing of action, and attention.
    • Cerebellar cortex:
      • Receives sensory input from spinal cord through cranial nerves.
      • Contains Purkinje cells.
      • Parallel fibers activate Purkinje cells one after another.
      • The more Purkinje cells activated, the longer their inhibitory message.
      • Inhibits nuclei in cerebellum and vestibular nuclei in the brain stem.

    Basal Ganglia

    • Spontaneous behavior, habits, and reward.
    • Striatum (caudate nucleus and putamen):
      • Receives input from cerebral cortex and substantia nigra.
      • Sends info to globus pallidus.
    • Globus pallidus:
      • Sends info to thalamus and frontal cortex.
    • 2 pathways:
      • Direct pathway: striatum inhibits globus pallidus, further inhibiting the thalamus.
      • Indirect pathway: inhibits competing movements.

    Movement Disorders

    • Parkinson's disease:
      • Gradual loss of dopamine-releasing axons from the substantia nigra.
      • Less inhibitory input to globus pallidus increases inhibitory signal to thalamus.
      • Symptoms: muscle tremors, slow movement, and difficulty initiating voluntary movements.
      • Treatment options: L-dopa treatment and experimenting with brain implants.
    • Huntington's disease:
      • Severe neurological disorder due to damaging protein huntington.
      • Symptoms: jerks, facial twitches, and tremors.
      • Extensive brain damage in basal ganglia and cerebral cortex.
      • Confirmed causal genetic relationship.### Oligodendrocytes and Schwann Cells
    • Oligodendrocytes are found within the brain and provide myelin for nerve cells
    • Schwann cells provide myelin for peripheral nerve cells
    • A single Schwann cell wraps a single segment of a peripheral nerve cell

    Neurotransmitters

    • Neurotransmitters are secreted from the axon terminal
    • Autoreceptors are located on the presynaptic membrane

    Lesions

    • A sham lesion is required for the control group when performing a lesion
    • A key advantage of a reversible lesion is that axons of passage are not affected by reversible procedures and each animal can serve as its own control

    Myelination

    • Myelination allows for quick and efficient transmission of action potential
    • Myelination does not change the height of action potential
    • Myelination does not increase the energy requirement of a nerve cell

    Action Potential

    • Hyperpolarization is when the potential becomes overly negative, usually due to potassium (K+) ions
    • If a stimulus reaches -60 mV, no action potential occurs

    Receptors

    • Ionotropic receptors directly open an ion channel
    • Metabotropic receptors use G protein activation to activate a second messenger, leading to a longer-lived effect on ion channels

    Brain Structure

    • Cerebrospinal fluid is produced within the ventricles
    • The parietal lobe is involved in somatosensory function
    • The occipital lobe is involved in visual function
    • The temporal lobe is involved in auditory function
    • The basal ganglia consists of the putamen, globus pallidus, and caudate nucleus, but not the amygdala
    • The ventral visual stream projects to the temporal lobe and is involved in object recognition

    Auditory System

    • The correct order of the auditory system is: auditory canal, eardrum, stirrup, anvil, and hammer, oval window and cochlea, hair cells

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    This quiz covers the material from lectures 5-7 of session 2 in a biopsychology course, including practical information and preparation for a partial exam.

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