Biology Module 1 Exam Review
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Questions and Answers

What is the primary role of mitochondria in a cell?

  • Protein synthesis
  • Cell division
  • Transport of materials
  • Energy production (correct)

Gram-negative bacteria have a thicker peptidoglycan layer than gram-positive bacteria.

False (B)

What are DAMPS and PAMPS in the context of the innate immune response?

DAMPS are damage-associated molecular patterns, and PAMPS are pathogen-associated molecular patterns.

The inflammatory response is primarily aimed at _________ and clearing out pathogens.

<p>preventing damage</p> Signup and view all the answers

Match the following components of the immune response with their descriptions:

<p>B cells = Cells responsible for producing antibodies T cells = Cells that may kill infected host cells directly Innate immune response = Immediate and non-specific response to pathogens Adaptive immune response = Slow but specific response to pathogens</p> Signup and view all the answers

Which of the following are the three major pathways of the complement system?

<p>Classical, lectin, and alternative (C)</p> Signup and view all the answers

IgM and IgG are immunoglobulins that indicate historical exposure to infections.

<p>True (A)</p> Signup and view all the answers

What term describes the process by which antibodies coat pathogens to enhance their phagocytosis?

<p>opsonization</p> Signup and view all the answers

The four types of hypersensitivity reactions can be remembered with the acronym ACID, with A representing __________.

<p>Allergic/Anaphylactic/Atopic</p> Signup and view all the answers

Match the following genetic transmission types with their characteristics:

<p>Autosomal dominant = Only one copy of the mutated gene is needed for a trait to be expressed Autosomal recessive = Two copies of the mutated gene must be present for the trait to be expressed X-linked dominant = Trait expressed with one mutated gene on the X chromosome X-linked recessive = Trait expressed primarily in males when a single mutated gene is present on the X chromosome</p> Signup and view all the answers

Flashcards

What is the cell membrane's role?

The cell membrane is a thin, flexible barrier that encloses the cell and controls what enters and leaves.

What is the role of ribosomes?

Ribosomes are responsible for protein synthesis. They read genetic information from messenger RNA (mRNA) and assemble amino acids into proteins.

What is Mitosis?

Mitosis is a type of cell division that produces two identical daughter cells from a single parent cell. It's used for growth and repair.

What is Meiosis?

Meiosis is a type of cell division that produces four non-identical daughter cells, each with half the chromosomes of the parent cell. It's used for sexual reproduction.

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What is innate immunity?

Innate immunity is the body's first line of defense against infection. It's non-specific and works immediately against any foreign invader.

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Classical Complement Pathway

The classical pathway is triggered by antigen-antibody complexes, leading to activation of complement proteins and opsonization.

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Lectin Complement Pathway

The lectin pathway is triggered by the binding of mannose-binding lectin (MBL) to carbohydrate structures on microbial surfaces.

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Alternative Complement Pathway

The alternative pathway is activated by microbial surface components, such as LPS, and does not require antibodies.

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Opsonization

Opsonization is a process that enhances phagocytosis. It involves coating microbes with complement proteins (like C3b) and other immune factors, making them more recognizable and digestible by phagocytes.

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CRISPR

CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. It's a gene editing tool that allows researchers to precisely modify DNA sequences.

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Study Notes

Module 1 Exam Review

  • Review of exam questions and answer choices are shown
  • Various topics related to cell structure, mitosis, meiosis, immune and adaptive immune responses, bacteria, viruses, fungal infections, prions, inflammation, complement and complex system, immunoglobulins, hypersensitivity reactions and genetic transmission.
  • Review of CRISPR, epigenetics, and their implications

Cell Structure

  • Understand the roles of organelles (Mitochondria, Golgi apparatus, Cell membrane, Ribosomes).

Mitosis

  • Review each mitosis phase.
  • Understand how chromatids form.

Meiosis

  • Review each meiosis phase.
  • Compare and contrast meiosis and mitosis.
  • Understand the purpose of meiosis.

Innate Immune Response

  • Identify cells involved in innate immune response.
  • Recognize host defenses against pathogens.
  • Identify components and their roles for inflammation.

Adaptive Immune Response

  • Identify cells involved in adaptive immune response.
  • Understand DAMPS, PAMPS, and TLRs.
  • Identify cells responsible for antibody creation.

Bacteria

  • Distinguish between gram-positive and gram-negative bacteria.
  • Identify infections caused by endotoxins and exotoxins.
  • Understand how bacteria protect themselves against innate immune system cells.

Viruses

  • Understand virus replication mechanisms.
  • Understand retroviruses (and why HIV is one).
  • Recognize cells responding to viral invasion.
  • Understand how viruses avoid immune surveillance.
  • Identify primary targets of HIV/AIDS.

Fungal Infections

  • Understand fungal transmission mechanisms (e.g., inhaled spores in lung infections)
  • Identify common fungal infections in immunocompromised individuals.

Prions

  • Define prions.
  • Understand prion infection mechanisms.
  • Recognize diseases caused by prions.

Inflammation

  • Differentiate between acute and chronic inflammation.
  • Understand the primary response to infection.

Complement and Complex System

  • Understand the 3 major complement pathways (classical, lectin, and alternative).
  • Understand opsonization.
  • Understand the role of complements and complexes in immune defense.

Immunoglobulins

  • Understand the roles of different immunoglobulins in the immune system.
  • Understand the structures of different immunoglobulins.
  • Understand how IgM and IgG indicate exposure to infection.

Hypersensitivity Reactions

  • Understand the four types of hypersensitivity reactions (A,C,I,D).
  • Recognize examples of each type.

Genetics

  • Know different types of genetic transmission: Autosomal dominant, Autosomal recessive, X-linked dominant, X-link recessive, and Mitochondrial.

CRISPR

  • Understand CRISPR mechanisms.
  • Review ethical issues associated with CRISPR.

Epigenetics

  • Understand how epigenetics influence human genome change.
  • Understand the possible reasons behind increased chromosomal abnormalities with older maternal and paternal ages.

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Module 1 Exam Review PDF

Description

Prepare for your Biology Module 1 exam with this comprehensive review quiz. It covers key topics including cell structure, mitosis, meiosis, immune responses, and the implications of CRISPR and epigenetics. Test your knowledge on various aspects of cellular biology and the immune system essential for understanding medical biology.

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