Biology Module 1 Exam Review

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Questions and Answers

What is the primary role of mitochondria in a cell?

  • Photosynthesis
  • Cell division
  • Energy production (correct)
  • Protein synthesis

Meiosis produces genetically identical cells.

False (B)

What are DAMPS and PAMPS?

DAMPS are damage-associated molecular patterns, and PAMPS are pathogen-associated molecular patterns.

Bacteria are classified as either ______ or ______ based on the structure of their cell wall.

<p>gram positive, gram negative</p> Signup and view all the answers

Match the immune cells with their primary functions:

<p>B cells = Produce antibodies T cells = Kill infected cells Macrophages = Engulf pathogens Neutrophils = Fight bacterial infections</p> Signup and view all the answers

Which of the following are the three major pathways of the complement system?

<p>Classical, Lectin, Alternative (B)</p> Signup and view all the answers

Opsonization is a process that promotes phagocytosis by marking pathogens for destruction.

<p>True (A)</p> Signup and view all the answers

What are the four types of hypersensitivity reactions?

<p>Type I: Allergic/Anaphylactic/Atopic, Type II: Cytotoxic, Type III: Immune complex deposition, Type IV: Delayed</p> Signup and view all the answers

The __________ type of genetic transmission involves a mutation that can be passed from an affected parent to 50% of their offspring regardless of gender.

<p>Autosomal dominant</p> Signup and view all the answers

Match the type of immunoglobulin with its primary function:

<p>IgA = Mucosal immunity IgE = Allergic responses IgM = First antibody produced IgG = Most abundant in serum</p> Signup and view all the answers

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Flashcards

Mitosis

A type of cell division that produces two identical daughter cells, each with the same number of chromosomes as the parent cell.

Meiosis

A type of cell division that produces four daughter cells, each with half the number of chromosomes as the parent cell. This is essential for sexual reproduction.

Mitochondria

The powerhouse of the cell. It is responsible for producing energy (ATP) through cellular respiration.

Ribosomes

Small, round organelles that are responsible for protein synthesis. Proteins are essential for many cellular functions.

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Cell membrane

A thin, flexible membrane that encloses the cell and controls what goes in and out. It is selectively permeable, meaning it allows some substances to pass through while blocking others.

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Complement System

A system of proteins that work together to defend against pathogens, involving three main pathways: classical, lectin, and alternative. These pathways lead to a cascade of events that activate inflammatory responses, attract immune cells, and eliminate pathogens.

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Opsonization

The process where antibodies bind to antigens on the surface of a pathogen, making it more easily identifiable and targeted by phagocytic cells.

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Type I Hypersensitivity

A type of hypersensitivity reaction triggered by the binding of IgE antibodies to mast cells, which release histamine and other inflammatory mediators, causing immediate allergic responses.

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Type II Hypersensitivity

A type of hypersensitivity reaction caused by the binding of antibodies to antigens on the surface of cells, leading to the destruction of those cells by complement activation or immune cells.

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Type III Hypersensitivity

A type of hypersensitivity reaction that involves the formation of immune complexes (antigen-antibody complexes) that deposit in tissues, triggering inflammation and tissue damage.

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Study Notes

Module 1 Exam Review

  • Review of module 1 material is required for the exam
  • Study of cell structure and organelles, including mitochondria, Golgi apparatus, cell membrane, and ribosomes is necessary.
  • Understanding the phases of mitosis and how chromatids form is crucial.
  • Review of meiosis, including phases, comparison with mitosis, and purpose.
  • Review of innate immune response; including cells involved, host defenses, and initial inflammatory response.
  • Review of adaptive immune response; including cells involved, DAMPS, PAMPS, TLRs, and antibody creation.
  • Study of bacteria, including differences between gram-positive and gram-negative bacteria, infections caused by endotoxins and exotoxins, and bacterial defense mechanisms.
  • Review of viral mechanisms of replication, retroviruses (HIV as an example), response to viral invasion, methods of avoiding immune surveillance, and primary targets within HIV/AIDS.
  • Study of fungal infections, transmission mechanisms (including inhaled spores in lung infections), and common infections in immunocompromised patients.
  • Study of prions, their nature, infection mechanisms, and associated disorders.
  • Understanding the difference between acute and chronic inflammation, and the primary response to infection is necessary.
  • Review of the complement and complex system, including pathways (classical, lectin, and alternative), opsonization, and complements' role in immune defense.
  • Study of immunoglobulins, including their roles in the immune system, structures, and how levels of IgM and IgG can indicate infection exposure.

Hypersensitivity Reactions

  • There are four types of hypersensitivity reactions (ACID or ABCD).
  • It's important to know the examples of each type (allergic/anaphylactic/atopic, cytotoxic, immune complex deposition, delayed hypersensitivity) and to note the abbreviations and mnemonic device (ACID or ABCD)

Genetics

  • Review of genetic transmission types: autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive, and mitochondrial inheritance.

CRISPR

  • Study the CRISPR mechanism (how it works).
  • Review of ethical issues related to CRISPR technology.
  • Review of live session videos or slides for further understanding, if available.

Epigenetics

  • Review of how epigenetics influences human genome changes over time.
  • Understand the potential reasons for increased chromosomal abnormalities with advanced maternal and paternal age.

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Module 1 Exam Review PDF

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