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Questions and Answers
Which part of the nervous system is responsible for involuntary actions such as heart rate and digestion?
Which part of the nervous system is responsible for involuntary actions such as heart rate and digestion?
The myelination of nerve fibers increases the speed of nerve impulse transmission.
The myelination of nerve fibers increases the speed of nerve impulse transmission.
True
What are the two main types of postsynaptic potentials?
What are the two main types of postsynaptic potentials?
Excitatory postsynaptic potential (EPSP) and inhibitory postsynaptic potential (IPSP)
The structural unit of the nervous system is called a ______.
The structural unit of the nervous system is called a ______.
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Match the following brain structures with their primary functions:
Match the following brain structures with their primary functions:
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What triggers the release of neurotransmitters in the presynaptic knob?
What triggers the release of neurotransmitters in the presynaptic knob?
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Neurotransmitters can only be degraded by enzymes and cannot be taken up by the presynaptic cell.
Neurotransmitters can only be degraded by enzymes and cannot be taken up by the presynaptic cell.
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What happens after neurotransmitters bind to receptors on the postsynaptic membrane?
What happens after neurotransmitters bind to receptors on the postsynaptic membrane?
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When an action potential arrives, Ca2+ channels open and __________ moves into the presynaptic knob.
When an action potential arrives, Ca2+ channels open and __________ moves into the presynaptic knob.
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Match the following processes with their descriptions:
Match the following processes with their descriptions:
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What occurs during depolarization of the membrane potential?
What occurs during depolarization of the membrane potential?
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The all-or-none principle states that action potentials can vary in amplitude based on the degree of depolarization.
The all-or-none principle states that action potentials can vary in amplitude based on the degree of depolarization.
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What happens to the membrane potential during repolarization?
What happens to the membrane potential during repolarization?
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After-hyperpolarization occurs when the permeability of K+ remains high for a period of _____ seconds.
After-hyperpolarization occurs when the permeability of K+ remains high for a period of _____ seconds.
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Match the stages of an action potential with their characteristics:
Match the stages of an action potential with their characteristics:
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What role do astrocytes play in the nervous system?
What role do astrocytes play in the nervous system?
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Microglia are responsible for forming the myelin sheath in the CNS.
Microglia are responsible for forming the myelin sheath in the CNS.
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Which cells provide myelination in the peripheral nervous system (PNS)?
Which cells provide myelination in the peripheral nervous system (PNS)?
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____ cells provide metabolic support to neurons and help maintain the blood-brain barrier.
____ cells provide metabolic support to neurons and help maintain the blood-brain barrier.
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Match the type of glial cell to their function:
Match the type of glial cell to their function:
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What do Schwann cells form around an axon in the PNS?
What do Schwann cells form around an axon in the PNS?
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Unmyelinated axons have nodes of Ranvier.
Unmyelinated axons have nodes of Ranvier.
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What is the primary function of the axon in a neuron?
What is the primary function of the axon in a neuron?
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What primarily affects the conduction velocities of nerve fibers?
What primarily affects the conduction velocities of nerve fibers?
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Myelinated nerves with the smallest diameter have the highest conduction velocities.
Myelinated nerves with the smallest diameter have the highest conduction velocities.
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Name a neurotoxin that blocks voltage-gated Na+ channels.
Name a neurotoxin that blocks voltage-gated Na+ channels.
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Neurotoxins interfere with the normal function of the __________ system.
Neurotoxins interfere with the normal function of the __________ system.
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Match the following neurotoxins with their sources:
Match the following neurotoxins with their sources:
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Which neurotoxin is toxic at nanomolar concentrations?
Which neurotoxin is toxic at nanomolar concentrations?
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Presence of myelin decreases nerve conduction velocities.
Presence of myelin decreases nerve conduction velocities.
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What are the factors that determine conduction velocities of nerve fibers?
What are the factors that determine conduction velocities of nerve fibers?
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What is the function of serotonin in relation to mental health?
What is the function of serotonin in relation to mental health?
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The transmission of action potentials in axons can occur in both directions.
The transmission of action potentials in axons can occur in both directions.
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What neurotransmitter is commonly targeted by benzodiazepines to reduce anxiety?
What neurotransmitter is commonly targeted by benzodiazepines to reduce anxiety?
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Morphine is used primarily as a __________.
Morphine is used primarily as a __________.
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Match the following neurotransmitters with their effects:
Match the following neurotransmitters with their effects:
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Why do myelinated axons conduct action potentials faster than unmyelinated axons?
Why do myelinated axons conduct action potentials faster than unmyelinated axons?
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Anions have a higher concentration outside the cell compared to inside, resulting in a positive equilibrium potential.
Anions have a higher concentration outside the cell compared to inside, resulting in a positive equilibrium potential.
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What is the primary anatomical organization of neurons that contribute to behavioral activity called?
What is the primary anatomical organization of neurons that contribute to behavioral activity called?
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Study Notes
Nervous System Physiology
- The nervous system is divided into central nervous system (CNS) and peripheral nervous system (PNS).
- The CNS includes the brain and spinal cord.
- The PNS contains nerve fibers and ganglia.
- Sensory (afferent) pathways transmit information toward the CNS.
- Motor (efferent) pathways transmit information away from the CNS.
- Somatic nervous system controls voluntary movements.
- Autonomic nervous system controls involuntary functions (e.g., heart rate, digestion).
- Sympathetic and parasympathetic systems are parts of the autonomic nervous system.
Neuron Structure and Function
- Neurons are the basic units of the nervous system.
- Neurons have cell bodies (soma), dendrites, and axons.
- Dendrites receive signals.
- Axons transmit signals.
- Synapses are junctions between neurons.
- Glial cells support and protect neurons.
Neuron Electrical Properties
- Resting membrane potential is the electrical potential across a neuron at rest (-70mV).
- Action potentials are rapid, large changes in membrane potential that transmit signals.
- Action potential arise from changes in permeability of the membrane to ions.
- There are 3 phases: rising, falling and recovery, in action potential.
- Concentration gradients across the membrane, specific ion channels, and their permeability to ions are key to creating the resting potential.
Nerve Impulse Transmission
- Myelinated axons transmit signals faster than unmyelinated axons.
- The myelin sheath insulates the axon, increasing the speed of signal transmission.
- In unmyelinated axons, the signal propagates continuously.
- In myelinated axons, the signal jumps between nodes of Ranvier—a phenomenon called saltatory conduction.
Synaptic Transmission
- Synapses are junctions between neurons.
- Chemical synapses use neurotransmitters to transmit signals.
- Electrical synapses transmit signals directly through gap junctions.
- Neurotransmitters bind to receptors on the postsynaptic neuron, causing either an excitatory (depolarizing) or inhibitory (hyperpolarizing) postsynaptic potential (PSP).
Neurotransmitters
- Neurotransmitters are chemical messengers that transmit signals across synapses.
- Examples of neurotransmitters include acetylcholine, glutamate, GABA, and others.
- Neurotransmitters can have varied effects depending upon the receptor they bind.
- Neurotransmitters are categorized into various classes including amino acids, biogenic amines, peptides, etc.
Neural Integration
- Neural circuits are networks of interconnected neurons that process information.
- Divergent pathways allow one presynaptic neuron to influence multiple postsynaptic neurons.
- Convergent pathways allow multiple presynaptic neurons to influence a single postsynaptic neuron.
- Summation refers to the combining of graded potentials in relation to thresholding.
Types of Synapses
- Electrical synapses pass signals very quickly directly through gap junctions.
- Chemical synapses use neurotransmitters that bind to receptors, triggering post-synaptic potentials (PSPs)
- Types of chemical synapses include ionotropic (fast) and metabotropic (slow) chemical synapses
- Neurotransmitter receptors can be either ionotropic or metabotropic.
Neuronal Classifications
- Based on function, neurons can be categorized as sensory (afferent), motor (efferent), or interneurons.
- Based on structure, neurons are categorized as unipolar, bipolar, and multipolar.
- The differences in structure dictate their function and actions within the nervous system to aid in efficient cellular communication and response.
Glial Cells
- Supporting cells in the CNS.
- Glial cells (70-90% of the CNS cells) perform various functions: structural support, metabolic support, forming blood-brain-barrier and myelin sheath, removal of dead neurons.
- Different types of glial cells with different functions; Astrocytes, oligodendrocytes (CNS), schwann cells (PNS), microglia, ependymal cells.
Neurotoxins
- Neurotoxins are substances that interfere with the normal function of the nervous system, often impacting ion channels.
Key Definitions
- Action Potential: A rapid, large change in membrane potential that propagates along an axon.
- Graded Potential: A small, local change in membrane potential in response to a stimulus that does not necessarily propagate down the entire axon.
- Postsynaptic Potential: A change in the membrane potential of a postsynaptic neuron in response to neurotransmitters binding to receptors.
- Refractory Period: The period of time after an action potential during which the neuron cannot generate another action potential (absolute) or will only generate it with stronger stimuli (relative).
- EPSP: Excitatory postsynaptic potential (causes depolarization)
- IPSP: Inhibitory postsynaptic potential (causes hyperpolarization).
- Threshold Potential: The membrane potential at which an action potential is generated.
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Description
Test your knowledge on the nervous system with this quiz covering involuntary actions, neurotransmitter functions, and neural communication processes. Questions include matching brain structures with their functions, understanding postsynaptic potentials, and the impact of myelination on nerve impulses.