Podcast
Questions and Answers
What is the primary mechanism of action of Azathioprine and Mercaptopurine?
What is the primary mechanism of action of Azathioprine and Mercaptopurine?
- Activation of immune response
- Inhibition of dihydrofolate reductase (correct)
- Interference with microtubule function
- Direct inhibition of DNA polymerase
Which of the following is a potential side effect of Azathioprine and Mercaptopurine?
Which of the following is a potential side effect of Azathioprine and Mercaptopurine?
- Bone marrow suppression (correct)
- Peripheral neuropathy
- Hypoglycemia
- Hypertension
What is the primary function of Methotrexate in autoimmune diseases?
What is the primary function of Methotrexate in autoimmune diseases?
- Blocking folic acid absorption
- Enhancing DNA replication
- Inhibiting RNA synthesis
- Inhibiting dihydrofolate reductase (correct)
Which autoimmune disease can be managed with Methotrexate?
Which autoimmune disease can be managed with Methotrexate?
What is the main concern associated with long-term use of Azathioprine and Mercaptopurine?
What is the main concern associated with long-term use of Azathioprine and Mercaptopurine?
In which condition might a patient be prescribed Prednisone-resistant antibody-mediated idiopathic thrombocytopenia purpura?
In which condition might a patient be prescribed Prednisone-resistant antibody-mediated idiopathic thrombocytopenia purpura?
Which of the following is a potential adverse effect of Methotrexate therapy?
Which of the following is a potential adverse effect of Methotrexate therapy?
What is the main purpose of Azathioprine and Mercaptopurine in managing autoimmune diseases?
What is the main purpose of Azathioprine and Mercaptopurine in managing autoimmune diseases?
What is the primary effect of Methotrexate on DNA synthesis in cells?
What is the primary effect of Methotrexate on DNA synthesis in cells?
What is the primary role of Azathioprine and Mercaptopurine in the treatment of glomerulonephritis in Lupus patients?
What is the primary role of Azathioprine and Mercaptopurine in the treatment of glomerulonephritis in Lupus patients?
