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Biologic Therapies for Inflammatory Bowel Disease Quiz

Test your knowledge on biologic therapies used to treat inflammatory bowel disease, including chimeric monoclonal antibodies and other drugs like Cyclosporine and Methotrexate. Explore how most biologic treatments target Tumor Necrosis Factor (TNF) and are administered via IV. Learn about the roles of the Innate and Adaptive Immune Systems in combating pathogens.

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Questions and Answers

What is the primary mechanism of action of Azathioprine and Mercaptopurine?

Inhibition of dihydrofolate reductase

Which of the following is a potential side effect of Azathioprine and Mercaptopurine?

Bone marrow suppression

What is the primary function of Methotrexate in autoimmune diseases?

Inhibiting dihydrofolate reductase

Which autoimmune disease can be managed with Methotrexate?

<p>Rheumatoid Arthritis</p> Signup and view all the answers

What is the main concern associated with long-term use of Azathioprine and Mercaptopurine?

<p>Liver dysfunction</p> Signup and view all the answers

In which condition might a patient be prescribed Prednisone-resistant antibody-mediated idiopathic thrombocytopenia purpura?

<p>Immune thrombocytopenic purpura not responding to Prednisone</p> Signup and view all the answers

Which of the following is a potential adverse effect of Methotrexate therapy?

<p>Interstitial lung disease</p> Signup and view all the answers

What is the main purpose of Azathioprine and Mercaptopurine in managing autoimmune diseases?

<p>Suppressing immune activity</p> Signup and view all the answers

What is the primary effect of Methotrexate on DNA synthesis in cells?

<p>Inhibition</p> Signup and view all the answers

What is the primary role of Azathioprine and Mercaptopurine in the treatment of glomerulonephritis in Lupus patients?

<p>Immune suppression to reduce kidney damage</p> Signup and view all the answers

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