Biologic Therapies for Inflammatory Bowel Disease Quiz
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Questions and Answers

What is the primary mechanism of action of Azathioprine and Mercaptopurine?

  • Activation of immune response
  • Inhibition of dihydrofolate reductase (correct)
  • Interference with microtubule function
  • Direct inhibition of DNA polymerase

    • Which of the following is a potential side effect of Azathioprine and Mercaptopurine?

  • Bone marrow suppression (correct)
  • Peripheral neuropathy
  • Hypoglycemia
  • Hypertension

    • What is the primary function of Methotrexate in autoimmune diseases?

  • Blocking folic acid absorption
  • Enhancing DNA replication
  • Inhibiting RNA synthesis
  • Inhibiting dihydrofolate reductase (correct)

    • Which autoimmune disease can be managed with Methotrexate?

    <p>Rheumatoid Arthritis</p> Signup and view all the answers

    What is the main concern associated with long-term use of Azathioprine and Mercaptopurine?

    <p>Liver dysfunction</p> Signup and view all the answers

    In which condition might a patient be prescribed Prednisone-resistant antibody-mediated idiopathic thrombocytopenia purpura?

    <p>Immune thrombocytopenic purpura not responding to Prednisone</p> Signup and view all the answers

    Which of the following is a potential adverse effect of Methotrexate therapy?

    <p>Interstitial lung disease</p> Signup and view all the answers

    What is the main purpose of Azathioprine and Mercaptopurine in managing autoimmune diseases?

    <p>Suppressing immune activity</p> Signup and view all the answers

    What is the primary effect of Methotrexate on DNA synthesis in cells?

    <p>Inhibition</p> Signup and view all the answers

    What is the primary role of Azathioprine and Mercaptopurine in the treatment of glomerulonephritis in Lupus patients?

    <p>Immune suppression to reduce kidney damage</p> Signup and view all the answers

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