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Bacterial Virulence Factors: Teichoic Acid and Septic Shock

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33 Questions

What is the term used for a short pilus that is used to attach a bacterium to a surface?

Fimbria

What is the main role of fimbriae (pili) in bacteria?

To mediate the attachment of bacteria to specific receptors on the human cell surface

What is the specialized type of pilus that forms the attachment between the male (donor) and the female (recipient) bacteria during conjugation?

Sex pilus

What is the key difference between the intracellular structures of bacteria and eukaryotes?

Bacteria do not contain membrane-enclosed organelles, while eukaryotes do.

What is the main function of the bacterial chromosome?

To encode the genetic information for the bacterial cell.

What is the role of plasmids in bacteria?

To be smaller, circular, extrachromosomal pieces of DNA that can be easily gained or lost by a bacterium and can be transferred between bacteria via horizontal gene transfer.

What is the main function of ribosomes in bacteria?

To produce proteins through the process of protein synthesis.

What is the purpose of endospore formation in bacteria?

To allow the bacterial cell to enter a dormant, resistant state in response to environmental stress.

What is the main difference between the structure of bacterial and eukaryotic ribosomes?

Bacterial ribosomes are smaller than eukaryotic ribosomes.

What is the significance of the location of an endospore within a bacterial cell?

It determines the species of the bacterium.

Which of the following organisms require oxygen to live?

Aerobes

What is the term used for organisms that can live with or without oxygen?

Facultative organisms

Which of the following terms describes organisms that grow best at very high temperatures (above 100°C)?

Hyperthermophiles

Most bacteria in the human body grow best at which pH range?

pH 7.2-7.5

Which of the following elements is a major component of bacterial proteins, structures, and membranes?

Carbon

Which of the following elements serves as a cofactor for enzymes and as a basic cation in bacterial cells?

Potassium

What is the main reason less ATP is produced during fermentation compared to aerobic respiration?

The reduction-oxidation potential is less for fermentation reactions

Which of the following statements about fermentation is true?

ATP is synthesized from an energy-rich intermediate

Which fermentation pathway is most common in bacteria?

Lactic acid fermentation

What is the name of the most common glycolytic pathway that occurs under both aerobic and anaerobic conditions?

Embden Meyerhof-Parnas (EMP) pathway

Which of the following is NOT an example of a fermentation product mentioned in the text?

Vinegar

What structures are located in the outer layer of the gram-positive cell wall and extend from it?

Teichoic Acid Fibers

Which component of the gram-negative cell wall is considered Endotoxin?

Lipopolysaccharide (LPS)

What is the lipid portion of the outer membrane of gram-negative bacteria impermeable to?

Many molecules

Which channels in gram-negative bacteria allow the movement of hydrophilic low-molecular-weight substances, ions, sugars, and amino acids?

Porins

What is the medical importance of Teichoic Acid Fibers in gram-positive bacteria?

Activating pathways similar to LPS in gram-negative bacteria

Which units make up the Lipopolysaccharide (LPS) of the outer membrane of gram-negative bacteria?

Lipid A, core polysaccharide, and O-specific polysaccharide

What is the function of flagella in bacteria?

Aids in bacterial motility through chemotaxis

Which structure of the flagella is responsible for bacterial motility?

Motor complex

What is the function of glycocalyx in bacteria?

Protection from phagocytosis and desiccation

Which external structure of bacteria is involved in the formation of biofilms?

Slime layer

What is the main difference between a capsule and a slime layer in bacteria?

Capsules are impermeable structures, while slime layers are permeable.

What is the purpose of fimbriae (pili) on the surface of bacteria?

Attachment to other cells or surfaces

Explore the role of teichoic acid fibers in the gram-positive cell wall and how they contribute to bacterial virulence factors such as adherence and septic shock. Understand the medical importance of teichoic acids in inducing septic shock and activating inflammatory responses.

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