10 Questions
What is the main function of the constant membrane proteins of the heavy chains in a B cell receptor (BCR)?
Deliver intracellular signals following antigen recognition
What is the significance of the Fab region in a monomeric antibody?
It binds to antigens
Why is the Fc fragment of an antibody named 'Fragment crystallizable'?
It mediates effector functions like antibody-dependent cellular cytotoxicity
Where is the hinge region located in a BCR?
At the center, allowing bending of the molecule
What is the function of the hinge region in an antibody molecule?
Allows flexibility for independent movement of antigen-binding Fab regions
What does the fragment antigen-binding (Fab fragment) of an antibody bind to?
Antigens
Which antibody region is responsible for mediating effector functions like antibody-dependent cellular cytotoxicity?
'Fragment crystallizable' (Fc) region
What are the components making up a B cell receptor (BCR)?
Two heavy and two light chains joined by disulfide bonds with constant and variable regions
What happens to naive B cells that have not yet encountered antigens?
They remain dormant until activated by antigens
What is the role of the variable domain in both heavy and light chains of a B cell receptor?
Confers specificity in antigen binding
Test your knowledge on the structure of a B cell receptor, including the composition of its chains and regions. Learn about why the Fc fragment is named as such and the characteristics of the Fab region in a monomeric antibody.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
