Podcast
Questions and Answers
Which cells can co-activate B cells in response to non-self antigens?
Which cells can co-activate B cells in response to non-self antigens?
- T8 cells
- T4 cells (correct)
- Dendritic cells
- Macrophages
In the immune system with perfect immune tolerance, what should not be able to activate T cells or B cells?
In the immune system with perfect immune tolerance, what should not be able to activate T cells or B cells?
- Immunoglobulins
- Non self-antigens
- APCs
- Self-antigens (correct)
What is the consequence of T8 cells recognizing self-antigens under MHCI antigen presentation?
What is the consequence of T8 cells recognizing self-antigens under MHCI antigen presentation?
- Costimulation of an immune response
- Activation of B cells
- Destruction of cells holding self antigens (correct)
- Activation of T4 cells
Which cells are capable of synthesizing antibodies in response to non-self antigens?
Which cells are capable of synthesizing antibodies in response to non-self antigens?
What can lead to an autoimmune disease?
What can lead to an autoimmune disease?
Which of the following is NOT a potential consequence of tolerance breakdown?
Which of the following is NOT a potential consequence of tolerance breakdown?
What do auto-antibodies and auto-reactive immune cells characterize?
What do auto-antibodies and auto-reactive immune cells characterize?
What is the role of the MHC locus in autoimmunity?
What is the role of the MHC locus in autoimmunity?
Which type of immune tolerance is essential to prevent autoimmunity?
Which type of immune tolerance is essential to prevent autoimmunity?
What is the consequence of autoimmune responses in the body?
What is the consequence of autoimmune responses in the body?
Which type of cells recognize antigens 'carried' by MHC I?
Which type of cells recognize antigens 'carried' by MHC I?
What is the consequence of T4 cells recognizing non self-antigens under MHCII presentation?
What is the consequence of T4 cells recognizing non self-antigens under MHCII presentation?
What characterizes autoimmune T cells or B cells in the immune system with a defect in immune tolerance?
What characterizes autoimmune T cells or B cells in the immune system with a defect in immune tolerance?
What is the role of autoantibodies and auto-reactive immune cells in the context of autoimmune diseases?
What is the role of autoantibodies and auto-reactive immune cells in the context of autoimmune diseases?
Which type of immune response can be co-activated by B cells in response to non self-antigens?
Which type of immune response can be co-activated by B cells in response to non self-antigens?
What is the central purpose of the lecture on autoimmunity?
What is the central purpose of the lecture on autoimmunity?
What is the consequence of tolerance breakdown?
What is the consequence of tolerance breakdown?
Which immune tolerance is essential to prevent autoimmunity?
Which immune tolerance is essential to prevent autoimmunity?
What is the role of the MHC locus in autoimmunity?
What is the role of the MHC locus in autoimmunity?
What is the key factor characterizing autoimmunity?
What is the key factor characterizing autoimmunity?
