Autoimmunity Process & Pathophysiology Lecture Learning Objectives

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Which cells can co-activate B cells in response to non-self antigens?

T8 cells

T4 cells (correct)

Dendritic cells

Macrophages

In the immune system with perfect immune tolerance, what should not be able to activate T cells or B cells?

Immunoglobulins

Non self-antigens

APCs

Self-antigens (correct)

What is the consequence of T8 cells recognizing self-antigens under MHCI antigen presentation?

Costimulation of an immune response

Activation of B cells

Destruction of cells holding self antigens (correct)

Activation of T4 cells

Which cells are capable of synthesizing antibodies in response to non-self antigens?

B lymphocytes Signup and view all the answers

What can lead to an autoimmune disease?

Recognition of self-antigens as non-self antigens Signup and view all the answers

Which of the following is NOT a potential consequence of tolerance breakdown?

Auto-antibody formation Signup and view all the answers

What do auto-antibodies and auto-reactive immune cells characterize?

Autoimmunity Signup and view all the answers

What is the role of the MHC locus in autoimmunity?

Susceptibility to autoimmunity Signup and view all the answers

Which type of immune tolerance is essential to prevent autoimmunity?

Ignorance (hidden and sequestrated antigens) Signup and view all the answers

What is the consequence of autoimmune responses in the body?

Formation of auto-antibodies Signup and view all the answers

Which type of cells recognize antigens 'carried' by MHC I?

T8 cells Signup and view all the answers

What is the consequence of T4 cells recognizing non self-antigens under MHCII presentation?

Costimulation of an immune response against the cells with non self-antigens Signup and view all the answers

What characterizes autoimmune T cells or B cells in the immune system with a defect in immune tolerance?

Activation by non self-antigens Signup and view all the answers

What is the role of autoantibodies and auto-reactive immune cells in the context of autoimmune diseases?

Targeting of self-antigens Signup and view all the answers

Which type of immune response can be co-activated by B cells in response to non self-antigens?

Immune response against non self-antigens Signup and view all the answers

What is the central purpose of the lecture on autoimmunity?

To introduce the concept of autoimmune responses and discuss the breakdown of immune tolerance Signup and view all the answers

What is the consequence of tolerance breakdown?

Selection (e.g., Thymus) Signup and view all the answers

Which immune tolerance is essential to prevent autoimmunity?

Central and Peripheral immune tolerance Signup and view all the answers

What is the role of the MHC locus in autoimmunity?

It plays a role in the susceptibility of autoimmunity Signup and view all the answers

What is the key factor characterizing autoimmunity?

Presence of auto-antibodies and auto-reactive immune cells Signup and view all the answers

Autoimmunity Process & Pathophysiology Lecture Learning Objectives

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Questions and Answers

Which cells can co-activate B cells in response to non-self antigens?

In the immune system with perfect immune tolerance, what should not be able to activate T cells or B cells?

What is the consequence of T8 cells recognizing self-antigens under MHCI antigen presentation?

Which cells are capable of synthesizing antibodies in response to non-self antigens?

What can lead to an autoimmune disease?

Which of the following is NOT a potential consequence of tolerance breakdown?

What do auto-antibodies and auto-reactive immune cells characterize?

What is the role of the MHC locus in autoimmunity?

Which type of immune tolerance is essential to prevent autoimmunity?

What is the consequence of autoimmune responses in the body?

Which type of cells recognize antigens 'carried' by MHC I?

What is the consequence of T4 cells recognizing non self-antigens under MHCII presentation?

What characterizes autoimmune T cells or B cells in the immune system with a defect in immune tolerance?

What is the role of autoantibodies and auto-reactive immune cells in the context of autoimmune diseases?

Which type of immune response can be co-activated by B cells in response to non self-antigens?

What is the central purpose of the lecture on autoimmunity?

What is the consequence of tolerance breakdown?

Which immune tolerance is essential to prevent autoimmunity?

What is the role of the MHC locus in autoimmunity?

What is the key factor characterizing autoimmunity?

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Autoimmunity Process &amp; Pathophysiology Lecture Learning Objectives

Podcast Beta

Questions and Answers

Which cells can co-activate B cells in response to non-self antigens?

In the immune system with perfect immune tolerance, what should not be able to activate T cells or B cells?

What is the consequence of T8 cells recognizing self-antigens under MHCI antigen presentation?

Which cells are capable of synthesizing antibodies in response to non-self antigens?

What can lead to an autoimmune disease?

Which of the following is NOT a potential consequence of tolerance breakdown?

What do auto-antibodies and auto-reactive immune cells characterize?

What is the role of the MHC locus in autoimmunity?

Which type of immune tolerance is essential to prevent autoimmunity?

What is the consequence of autoimmune responses in the body?

Which type of cells recognize antigens 'carried' by MHC I?

What is the consequence of T4 cells recognizing non self-antigens under MHCII presentation?

What characterizes autoimmune T cells or B cells in the immune system with a defect in immune tolerance?

What is the role of autoantibodies and auto-reactive immune cells in the context of autoimmune diseases?

Which type of immune response can be co-activated by B cells in response to non self-antigens?

What is the central purpose of the lecture on autoimmunity?

What is the consequence of tolerance breakdown?

Which immune tolerance is essential to prevent autoimmunity?

What is the role of the MHC locus in autoimmunity?

What is the key factor characterizing autoimmunity?

More Like This

MCQ Autoimmunity Quiz

Autoimmunity and Self-Tolerance Quiz

Guest Lecture: Multiple Sclerosis

Autoimmunity

Autoimmunity Process & Pathophysiology Lecture Learning Objectives