Autoimmune Diseases Seminar Quiz
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Questions and Answers

Which mechanism of immunologic tolerance involves the antigen-induced deletion of self-reactive T and B lymphocytes during their maturation?

  • Immunologic recognition
  • Peripheral tolerance
  • Central tolerance (correct)
  • Autoimmune activation
  • What is the state of unresponsiveness to an antigen (self-antigen) induced by exposure of specific lymphocytes to that antigen?

  • Autoimmune activation
  • Immunologic tolerance (correct)
  • Immunologic recognition
  • Antigenic unresponsiveness
  • Where does the maturation of T cells and B cells take place for the antigen-induced deletion of self-reactive lymphocytes?

  • Thymus and bone marrow (correct)
  • Lungs and kidneys
  • Liver and pancreas
  • Spleen and lymph nodes
  • Which objective of Seminar I involves the ability to correlate concepts to autoimmune diseases?

    <p>Objective 2</p> Signup and view all the answers

    What are the two broad mechanisms recognized for eliminating or controlling self-recognizing lymphocytes?

    <p>Central tolerance and peripheral tolerance</p> Signup and view all the answers

    Which mechanism of immunologic tolerance involves the antigen-induced deletion of self-reactive T and B lymphocytes during their maturation?

    <p>Central tolerance</p> Signup and view all the answers

    Where does the antigen-induced deletion of self-reactive T lymphocytes and B lymphocytes primarily occur?

    <p>Thymus and bone marrow</p> Signup and view all the answers

    What is the principal mechanism of central tolerance?

    <p>Antigen-induced deletion of self-reactive lymphocytes</p> Signup and view all the answers

    What is the state of unresponsiveness to an antigen (self-antigen) induced by exposure of specific lymphocytes to that antigen?

    <p>Immunologic tolerance</p> Signup and view all the answers

    What are the two broad mechanisms recognized for eliminating or controlling self-recognizing lymphocytes?

    <p>Central tolerance and peripheral tolerance</p> Signup and view all the answers

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