Podcast
Questions and Answers
Which mechanism of immunologic tolerance involves the antigen-induced deletion of self-reactive T and B lymphocytes during their maturation?
Which mechanism of immunologic tolerance involves the antigen-induced deletion of self-reactive T and B lymphocytes during their maturation?
- Immunologic recognition
- Peripheral tolerance
- Central tolerance (correct)
- Autoimmune activation
What is the state of unresponsiveness to an antigen (self-antigen) induced by exposure of specific lymphocytes to that antigen?
What is the state of unresponsiveness to an antigen (self-antigen) induced by exposure of specific lymphocytes to that antigen?
- Autoimmune activation
- Immunologic tolerance (correct)
- Immunologic recognition
- Antigenic unresponsiveness
Where does the maturation of T cells and B cells take place for the antigen-induced deletion of self-reactive lymphocytes?
Where does the maturation of T cells and B cells take place for the antigen-induced deletion of self-reactive lymphocytes?
- Thymus and bone marrow (correct)
- Lungs and kidneys
- Liver and pancreas
- Spleen and lymph nodes
Which objective of Seminar I involves the ability to correlate concepts to autoimmune diseases?
Which objective of Seminar I involves the ability to correlate concepts to autoimmune diseases?
What are the two broad mechanisms recognized for eliminating or controlling self-recognizing lymphocytes?
What are the two broad mechanisms recognized for eliminating or controlling self-recognizing lymphocytes?
Which mechanism of immunologic tolerance involves the antigen-induced deletion of self-reactive T and B lymphocytes during their maturation?
Which mechanism of immunologic tolerance involves the antigen-induced deletion of self-reactive T and B lymphocytes during their maturation?
Where does the antigen-induced deletion of self-reactive T lymphocytes and B lymphocytes primarily occur?
Where does the antigen-induced deletion of self-reactive T lymphocytes and B lymphocytes primarily occur?
What is the principal mechanism of central tolerance?
What is the principal mechanism of central tolerance?
What is the state of unresponsiveness to an antigen (self-antigen) induced by exposure of specific lymphocytes to that antigen?
What is the state of unresponsiveness to an antigen (self-antigen) induced by exposure of specific lymphocytes to that antigen?
What are the two broad mechanisms recognized for eliminating or controlling self-recognizing lymphocytes?
What are the two broad mechanisms recognized for eliminating or controlling self-recognizing lymphocytes?