10 Questions
Which mechanism of immunologic tolerance involves the antigen-induced deletion of self-reactive T and B lymphocytes during their maturation?
Central tolerance
What is the state of unresponsiveness to an antigen (self-antigen) induced by exposure of specific lymphocytes to that antigen?
Immunologic tolerance
Where does the maturation of T cells and B cells take place for the antigen-induced deletion of self-reactive lymphocytes?
Thymus and bone marrow
Which objective of Seminar I involves the ability to correlate concepts to autoimmune diseases?
Objective 2
What are the two broad mechanisms recognized for eliminating or controlling self-recognizing lymphocytes?
Central tolerance and peripheral tolerance
Which mechanism of immunologic tolerance involves the antigen-induced deletion of self-reactive T and B lymphocytes during their maturation?
Central tolerance
Where does the antigen-induced deletion of self-reactive T lymphocytes and B lymphocytes primarily occur?
Thymus and bone marrow
What is the principal mechanism of central tolerance?
Antigen-induced deletion of self-reactive lymphocytes
What is the state of unresponsiveness to an antigen (self-antigen) induced by exposure of specific lymphocytes to that antigen?
Immunologic tolerance
What are the two broad mechanisms recognized for eliminating or controlling self-recognizing lymphocytes?
Central tolerance and peripheral tolerance
Test your knowledge on autoimmune diseases with this seminar quiz. Covering basic concepts of autoimmunity, correlation to autoimmune diseases, and laboratory tests, this quiz will help you understand immunologic tolerance and its implications in autoimmune conditions.
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