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What key elements in the human body are mentioned as being relevant to MRI?
What key elements in the human body are mentioned as being relevant to MRI?
Which motion does not occur within an atom?
Which motion does not occur within an atom?
Which of the following nuclei is considered MR-active?
Which of the following nuclei is considered MR-active?
What is the primary reason hydrogen is used as the main MR-active nucleus in MRI?
What is the primary reason hydrogen is used as the main MR-active nucleus in MRI?
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What does Faraday’s law of electromagnetic induction describe?
What does Faraday’s law of electromagnetic induction describe?
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What does the magnetic moment of a nucleus represent?
What does the magnetic moment of a nucleus represent?
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Which of the following statements about the hydrogen nucleus is true?
Which of the following statements about the hydrogen nucleus is true?
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Which of the following is NOT a type of motion present within an atom?
Which of the following is NOT a type of motion present within an atom?
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What does AP stand for in anatomical terms?
What does AP stand for in anatomical terms?
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What is the primary use of the CISS sequence?
What is the primary use of the CISS sequence?
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Which technique is used for fluid suppression in brain studies?
Which technique is used for fluid suppression in brain studies?
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What does DESS stand for?
What does DESS stand for?
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What is the definition of acquisition time?
What is the definition of acquisition time?
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What are the characteristics of dual echo sequences?
What are the characteristics of dual echo sequences?
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Which of the following describes the purpose of ECG triggering?
Which of the following describes the purpose of ECG triggering?
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What is a characteristic of 3-D measurement in imaging?
What is a characteristic of 3-D measurement in imaging?
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What occurs to the magnetic moments of hydrogen nuclei in the absence of an applied magnetic field?
What occurs to the magnetic moments of hydrogen nuclei in the absence of an applied magnetic field?
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What is the result of magnetic moments aligning parallel to the main magnetic field (B0)?
What is the result of magnetic moments aligning parallel to the main magnetic field (B0)?
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What does the precession frequency (w0) depend on according to the Larmor equation?
What does the precession frequency (w0) depend on according to the Larmor equation?
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What happens to hydrogen nuclei at higher magnetic field strengths?
What happens to hydrogen nuclei at higher magnetic field strengths?
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How is the precessional frequency of hydrogen at 1.5 T expressed?
How is the precessional frequency of hydrogen at 1.5 T expressed?
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What characterizes the net magnetic vector (NMV) when magnetic moments align anti-parallel to B0?
What characterizes the net magnetic vector (NMV) when magnetic moments align anti-parallel to B0?
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What is true about the gyromagnetic ratio (γ) in relation to different MR-active nuclei?
What is true about the gyromagnetic ratio (γ) in relation to different MR-active nuclei?
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What occurs when hydrogen nuclei are placed parallel to the main magnetic field?
What occurs when hydrogen nuclei are placed parallel to the main magnetic field?
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What is the primary purpose of using ECG triggering during data acquisition in MRI?
What is the primary purpose of using ECG triggering during data acquisition in MRI?
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Which statement best describes dual echo sequences in MRI?
Which statement best describes dual echo sequences in MRI?
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What is the significance of the CISS sequence in MRI?
What is the significance of the CISS sequence in MRI?
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In the context of MRI, what does the term 'Dark fluid' refer to?
In the context of MRI, what does the term 'Dark fluid' refer to?
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What does the process of acquisition time in MRI refer to?
What does the process of acquisition time in MRI refer to?
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Which type of coils are mentioned in the context of signal transmission in MRI?
Which type of coils are mentioned in the context of signal transmission in MRI?
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Which imaging technique is defined by exciting the entire volume of interest instead of a single slice?
Which imaging technique is defined by exciting the entire volume of interest instead of a single slice?
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What characterizes the DESS sequence in MRI imaging?
What characterizes the DESS sequence in MRI imaging?
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What is the orientation of hydrogen nuclei when they align parallel to the main magnetic field (B0)?
What is the orientation of hydrogen nuclei when they align parallel to the main magnetic field (B0)?
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Which statement accurately describes precession frequency?
Which statement accurately describes precession frequency?
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What happens to the overall magnetic effect of hydrogen nuclei in the absence of an applied magnetic field?
What happens to the overall magnetic effect of hydrogen nuclei in the absence of an applied magnetic field?
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At a magnetic field strength of 1.5 T, what is the precessional frequency of hydrogen?
At a magnetic field strength of 1.5 T, what is the precessional frequency of hydrogen?
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Which characteristic of the net magnetic vector (NMV) corresponds to the alignment of hydrogen nuclei anti-parallel to the main magnetic field (B0)?
Which characteristic of the net magnetic vector (NMV) corresponds to the alignment of hydrogen nuclei anti-parallel to the main magnetic field (B0)?
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What does the gyromagnetic ratio (γ) signify in the context of MR-active nuclei?
What does the gyromagnetic ratio (γ) signify in the context of MR-active nuclei?
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In the Larmor equation, which variable represents precession frequency?
In the Larmor equation, which variable represents precession frequency?
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At which magnetic field strength is the precessional frequency of hydrogen nuclei the lowest according to the provided information?
At which magnetic field strength is the precessional frequency of hydrogen nuclei the lowest according to the provided information?
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What primarily determines the magnetic moment of a hydrogen nucleus in MRI?
What primarily determines the magnetic moment of a hydrogen nucleus in MRI?
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Which motion is NOT associated with the atomic structure described?
Which motion is NOT associated with the atomic structure described?
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What is the reason behind the use of protium in MRI imaging?
What is the reason behind the use of protium in MRI imaging?
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What does Faraday's law of electromagnetic induction imply about the behavior of charged particles?
What does Faraday's law of electromagnetic induction imply about the behavior of charged particles?
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Which component of an atom makes up most of its mass?
Which component of an atom makes up most of its mass?
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What best describes the function of hydrogen's magnetic moment in MRI?
What best describes the function of hydrogen's magnetic moment in MRI?
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Which of the following nuclei does NOT qualify as MR-active?
Which of the following nuclei does NOT qualify as MR-active?
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What happens when the magnetic moments of hydrogen nuclei are aligned anti-parallel to the main magnetic field?
What happens when the magnetic moments of hydrogen nuclei are aligned anti-parallel to the main magnetic field?
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What is the primary characteristic of the CISS sequence in MRI imaging?
What is the primary characteristic of the CISS sequence in MRI imaging?
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Which of the following best describes the dual echo measurement in MRI?
Which of the following best describes the dual echo measurement in MRI?
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In MRI, what does the term 'Dark fluid' specifically refer to?
In MRI, what does the term 'Dark fluid' specifically refer to?
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Which statement accurately reflects the purpose of ECG triggering in MRI?
Which statement accurately reflects the purpose of ECG triggering in MRI?
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What distinguishes a 3-D measurement technique from traditional imaging methods in MRI?
What distinguishes a 3-D measurement technique from traditional imaging methods in MRI?
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What does the acronym DESS stand for in the context of MRI imaging sequences?
What does the acronym DESS stand for in the context of MRI imaging sequences?
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Which type of coil is specifically known for enhancing signal reception in MRI?
Which type of coil is specifically known for enhancing signal reception in MRI?
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What occurs to the magnetic moments of hydrogen nuclei when they align parallel to the main magnetic field (B0)?
What occurs to the magnetic moments of hydrogen nuclei when they align parallel to the main magnetic field (B0)?
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What is a major advantage of the Turbo inversion recovery sequence used in MRI?
What is a major advantage of the Turbo inversion recovery sequence used in MRI?
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How is the precession frequency (w0) calculated according to the Larmor equation?
How is the precession frequency (w0) calculated according to the Larmor equation?
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What happens to the precession frequency of hydrogen nuclei when the magnetic field strength is increased?
What happens to the precession frequency of hydrogen nuclei when the magnetic field strength is increased?
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In the context of MR-active nuclei, what does the gyromagnetic ratio (γ) represent?
In the context of MR-active nuclei, what does the gyromagnetic ratio (γ) represent?
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At a magnetic field strength of 0.5 T, what is the precessional frequency of hydrogen nuclei?
At a magnetic field strength of 0.5 T, what is the precessional frequency of hydrogen nuclei?
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Which orientation of magnetic moments corresponds to high energy states in hydrogen nuclei?
Which orientation of magnetic moments corresponds to high energy states in hydrogen nuclei?
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What is the characteristic of the net magnetic vector (NMV) when hydrogen nuclei align anti-parallel to B0?
What is the characteristic of the net magnetic vector (NMV) when hydrogen nuclei align anti-parallel to B0?
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How do different MR-active nuclei influence precessional frequencies at various field strengths?
How do different MR-active nuclei influence precessional frequencies at various field strengths?
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Which property is primarily responsible for the hydrogen nucleus being an effective MR-active nucleus?
Which property is primarily responsible for the hydrogen nucleus being an effective MR-active nucleus?
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What type of motion occurs within the nucleus of an atom that enhances its magnetic properties?
What type of motion occurs within the nucleus of an atom that enhances its magnetic properties?
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Faraday's law indicates the relationship between which two phenomena?
Faraday's law indicates the relationship between which two phenomena?
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Why is protium specifically chosen for MRI instead of other isotopes of hydrogen?
Why is protium specifically chosen for MRI instead of other isotopes of hydrogen?
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Which of the following elements is NOT considered MR-active based on their nuclei properties?
Which of the following elements is NOT considered MR-active based on their nuclei properties?
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What aspect of the atomic structure directly influences the strength of the magnetic field generated by the hydrogen nucleus?
What aspect of the atomic structure directly influences the strength of the magnetic field generated by the hydrogen nucleus?
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What does the term 'net spin' refer to in the context of MR-active nuclei?
What does the term 'net spin' refer to in the context of MR-active nuclei?
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In MRI, why is Faraday's law significant for understanding the behavior of MR-active nuclei?
In MRI, why is Faraday's law significant for understanding the behavior of MR-active nuclei?
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Study Notes
Atomic Structure
- All matter is made up of atoms that form molecules
- Key elements in the human body include hydrogen, oxygen, carbon, and nitrogen
- Atoms have a central nucleus with orbiting electrons
- Nucleus contains protons (positive charge) and neutrons (no charge)
- Electrons have a negative charge and orbit the nucleus
- The nucleus is tiny but contains most of the atom's mass
- The nucleus is composed of protons and neutrons (nucleons)
- The nucleus occupies a tiny fraction of the atom's volume
Motion of Atoms
- Electrons spin on their own axis
- Electrons orbit the nucleus
- The nucleus spins on its own axis
MR-active Nuclei
- A nucleus with an uneven number of protons and neutrons has a net spin and is MR-active:
- ¹H (hydrogen)
- ¹³C (carbon)
- ¹⁵N (nitrogen)
- ¹⁷O (oxygen)
- ¹⁹F (fluorine)
- ²³Na (sodium)
Hydrogen Nucleus
- The isotope of hydrogen called protium is the most commonly used MR-active nucleus
- It has a mass and atomic number of 1, and its nucleus consists of a single proton and no neutrons
- Hydrogen is abundant in the human body and its single proton gives it a large magnetic moment
- These characteristics mean the maximum amount of magnetization in the body is utilized
Faraday's Law of Electromagnetic Induction
- A magnetic field is created by a moving charged particle
- The protium nucleus contains one positively charged proton that spins, making it a moving charged particle, which creates a magnetic field.
- The nucleus acts as a small magnet with a north and south pole.
- The north/south axis of each nucleus is represented by a magnetic moment
- This magnetic moment can align with an external magnetic field (B0)
Alignment
- In the absence of an external magnetic field, the magnetic moments of hydrogen nuclei are randomly oriented
- When placed in a strong static external magnetic field, the magnetic moments align with the field.
- This alignment is called magnetization.
- Nuclei aligned parallel to the field have a low energy (referred to as "spin up" nuclei)
- Nuclei aligned anti-parallel to the field have a high energy (referred to as "spin down" nuclei)
Net Magnetic Vector (NMV)
- The NMV represents the overall magnetic field strength in a sample.
- It is proportional to the external magnetic field strength (B0).
Precession and Precessional (Larmor) Frequency
- The magnetic moments of hydrogen nuclei precess around the B0 field.
- Precession frequency (w0) is the speed at which magnetic moments precess around B0
- The Larmor equation relates precession frequency, magnetic field strength, and gyromagnetic ratio: w0 = γB0
- w0: precession frequency
- B0: magnetic field strength
- γ: gyromagnetic ratio (constant)
- Precession frequency is proportional to the strength of the magnetic field.
- For hydrogen:
- At 1.5 T, the precessional frequency is 63.87 MHz.
- At 1.0 T, the precessional frequency is 42.57 MHz.
- At 0.5 T, the precessional frequency is 21.29 MHz.
Atomic Structure
- All matter is composed of atoms.
- Atoms combine to form molecules.
- Key elements in the human body are hydrogen, oxygen, carbon, and nitrogen.
- Atoms have a central nucleus and orbiting electrons.
- The nucleus contains protons (positive charge) and neutrons (no charge).
- Electrons (negative charge) orbit the nucleus.
Mass and Size of Nucleus
- The nucleus is tiny but contains most of the atom's mass.
- It is composed of protons and neutrons (collectively known as nucleons).
- The nucleus occupies a minute fraction of an atom's volume.
Motion in the Atom
- Three types of motion occur within an atom:
- Electrons spinning on their own axis
- Electrons orbiting the nucleus
- The nucleus itself spinning about its own axis
MR-active Nuclei
- MR-active nuclei have a net spin, meaning their protons and neutrons are not equal, resulting in a magnetic moment.
- Common MR-active nuclei include:
- 1H (hydrogen)
- 13C (carbon)
- 15N (nitrogen)
- 17O (oxygen)
- 19F (fluorine)
- 23Na (sodium)
The Hydrogen Nucleus
- The isotope of hydrogen called protium is the most commonly used MR-active nucleus in MRI.
- It has a mass and atomic number of 1, meaning its nucleus consists of a single proton and no neutrons.
- Hydrogen is abundant in the human body and its single proton gives it a relatively large magnetic moment, maximizing the available magnetization for MRI.
Faraday’s Law of Electromagnetic Induction
- Faraday's law states that a magnetic field is created by a charged moving particle.
- The protium nucleus's spinning proton, being charged, induces a magnetic field around it, acting as a small magnet.
- Each hydrogen nucleus has a north and a south pole of equal strength, represented by its magnetic moment.
Alignment
- In the absence of an external magnetic field, hydrogen nuclei's magnetic moments are randomly oriented, producing no overall magnetic effect.
- When placed in a strong static external magnetic field (B0), the magnetic moments of hydrogen nuclei align with it, resulting in:
- Low energy: Nuclei aligned parallel to B0, referred to as "spine up" nuclei.
- High energy: Nuclei aligned anti-parallel to B0, referred to as "spine down" nuclei.
Net Magnetic Vector (NMV)
- The alignment of hydrogen nuclei in an external magnetic field creates a net magnetic vector (NMV), also known as net magnetization (M0).
- The strength of the NMV is directly proportional to the strength of the external magnetic field (B0).
Precession and Precessional (Larmor) Frequency
- When placed in an external magnetic field, hydrogen nuclei's magnetic moments precess around the field's axis.
- The speed of this precession is called the precessional frequency (ω0) and is determined by the Larmor equation: ω0 = γB0
- ω0: Precessional frequency
- B0: Magnetic field strength
- γ: Gyromagnetic ratio (a constant for a given nucleus)
Magnetic Characteristics of Common Elements
- The gyromagnetic ratio (γ) is a constant for a specific nucleus.
- At different field strengths, the precessional frequencies of MR-active nuclei vary.
- For hydrogen, at:
- 1.5 T: 63.87 MHz
- 1.0 T: 42.57 MHz
- 0.5 T: 21.29 MHz
Atomic Structure
- All matter is composed of atoms.
- Atoms combine to form molecules.
- Key elements in the human body: hydrogen, oxygen, carbon, nitrogen.
- Atoms have a central nucleus and orbiting electrons.
- Nucleus contains protons (positive charge) and neutrons (no charge).
- Electrons (negative charge) orbit the nucleus.
Mass and Size of Nucleus
- Nucleus is tiny but contains most of the atom's mass.
- Composed of protons and neutrons (nucleons).
- Nucleus occupies a minute fraction of an atom's volume.
Motion in the Atom
- Three types of motion are present within the atom:
- Electrons spinning on their own axis
- Electrons orbiting the nucleus
- The nucleus itself spinning about its own axis.
MR-active nuclei
- Protons and Neutrons:
- P=N Has no spine =0
- P≠N Has net spine≠0
- MR-active nuclei:
- 1H (hydrogen)
- 13C (carbon)
- 15N (nitrogen)
- 17O (oxygen)
- 19F (fluorine)
- 23Na (sodium).
The Hydrogen Nucleus
- The isotope of hydrogen called protium is the most commonly used MR-active nucleus in MRI.
- It has a mass and atomic number of 1, so the nucleus consists of a single proton and has no neutrons.
- It is used because hydrogen is very abundant in the human body and because the solitary proton gives it a relatively large magnetic moment.
- These characteristics mean that the maximum amount of available magnetization in the body is utilized.
Faraday's Law of Electromagnetic Induction
- Faraday's law of electromagnetic induction states that a magnetic field is created by a charged moving particle (that creates an electric field).
- The protium nucleus contains one positively charged proton that spins and moves.
- Therefore, the nucleus has a magnetic field induced around it and acts as a small magnet.
- The magnet of each hydrogen nucleus has a north and a south pole of equal strength.
- The north/south axis of each nucleus is represented by a magnetic moment and is used in classical theory.
- Motion + electricity = magnet
Alignment
- In the absence of an applied magnetic field, the magnetic moments of hydrogen nuclei are randomly orientated and produce no overall magnetic effect.
- However, when placed in a strong static external magnetic field, the magnetic moments of hydrogen nuclei orientate with this magnetic field.
- This is called alignment.
Net Magnetic Vector (NMV)
- Align parallel to the main magnetic field (B0) (Net magnetic vector, NMV)
- Low energy
- Spine up nuclei
- Align Anti-parallel to the main magnetic field (B0)
- High energy
- Spine down nuclei
Precession and Precessional (Larmor) Frequency
- Precession frequency: The speed at which magnetic moments preces around B0 is called Precession frequency (w0).
- Larmor equation:
- W0 = y B0
- Where:
- W0: is the Precession frequency
- B0: is the magnetic field strength of the magnet
- Y: is the gyromagnetic ratio
Glossary
- Acquisition time = Period of time required to collect the image data.
- AP Anteroposterior = from the front to the back of the body.
- Axial= Orthogonal to the long axis of the body.
- CISS= Constructive interference steady state: a sequence which supposedly minimizes the interference-induced artifacts of a true FISP sequence; the CISS sequence is heavily T2-weighted and currently is used primarily as a high-resolution 3-D sequence for the inner ear
- Coil =Transmission or reception unit for the signals transmitted/ received by the magnet. There are transmission, reception, and combined transmission/reception coils, and they come as body and surface coils, the latter being available as rigid and flexible (wraparound) coils.
- CSF = Cerebrospinal fluid.
- Dark fluid = Turbo inversion recovery sequence: a technique with a long TI (approx. 2200ms for 1.0 and 1.5 T) used for fluid suppression, e.g., for suppressing the CSF in brain and spinal studies with T2 weighting (and long TE).
- DESS = Dual echo steady state: gradient echo sequence where both axial and transverse magnetization adds to the signal, e.g.the FISP sequence and its temporally reversed form PSIF. In DESS the two sequences (FISP as a ratio of T1 to T2, and PSIF as mostly T2-weighted sequence) are added.
- 3-D measurement = Volume measurement: imaging technique where each pulse excites not just a single slice but the entire volume of interest.
- Dual echo = Dual measurement: sequences characterized by two readout times (TE) for one (comparatively long) TR. Normally dual echo combines proton-densityweighted (short TE) and T2-weighted (long TE) measurements.
- ECG triggering (EGG gating)= Triggered by the signals of the heart: data acquisition takes place only during particular phases of the cardiac cycle (e.g. during systole or diastole); the patient has to be attached to a set of ECG leads.
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Description
Explore the fundamental concepts of atomic structure and the motion of atoms in this quiz. Test your knowledge on key elements in the human body, the behavior of electrons and nuclei, as well as MR-active nuclei. Perfect for students studying chemistry and physics.