Atherosclerosis and Venous Thromboembolism Quiz
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Questions and Answers

What is the primary manifestation of Venous thromboembolism (VTE)?

  • Vascular injury and Hypercoagulability
  • Platelet-derived growth factor (PDGF) and Thrombocytes
  • Deep vein thrombosis (DVT) and Pulmonary embolism (PE) (correct)
  • Venous stasis and Coagulation cascade
  • What are the three primary components of Virchow’s triad, which contributes to clot formation in the venous circulation?

  • Coagulation cascade, Deep vein thrombosis (DVT), Pulmonary embolism (PE)
  • Venous stasis, Vascular injury, Hypercoagulability (correct)
  • Platelet-derived growth factor (PDGF), Thrombocytes, Serotonin
  • HemoStasis, Anticoagulant, Procoagulant mechanism
  • What is the function of Platelets during hemostasis?

  • To initiate vascular spasms
  • To regulate the coagulation cascade
  • To maintain the balance of blood
  • To provide a close barrier to stop bleeding (correct)
  • What are the three phases in rapid sequence during clot formation in hemostasis?

    <p>Vascular spasms, Platelet plug formation, Coagulation (blood clotting)</p> Signup and view all the answers

    What is the main function of a blood clot?

    <p>To contain formed elements of the blood entangled in fibrin threads</p> Signup and view all the answers

    What is the mechanism that prevents loss from damaged blood vessels?

    <p>HemoStasis</p> Signup and view all the answers

    What is the other name for Platelets?

    <p>Thrombocytes</p> Signup and view all the answers

    What do the granules in platelets contain?

    <p>Enzymes, ADP, Platelet-derived growth factor (PDGF)</p> Signup and view all the answers

    What is the immediate effect of Vascular spasms during hemostasis?

    <p>Vasoconstriction</p> Signup and view all the answers

    What is the process of breaking down a blood clot?

    <p>Fibrinolysis</p> Signup and view all the answers

    What is the main function of Anticoagulant mechanism during hemostasis?

    <p>Prevent excessive clotting</p> Signup and view all the answers

    What factor doubles with each 10 years after the age of 50, increasing the risk of clotting disorders?

    <p>Age</p> Signup and view all the answers

    What is the normal range for activated partial thrombin time (aPTT)?

    <p>10-30 seconds</p> Signup and view all the answers

    What is the main function of D-dimer in the diagnosis of VTE?

    <p>To detect degradation products of fibrin blood clots</p> Signup and view all the answers

    What is the primary manifestation of Post Thrombotic Syndrome (PTS)?

    <p>Chronic lower extremity swelling, pain, and skin discoloration</p> Signup and view all the answers

    Which condition is associated with high red blood cell production and poses a risk for VTE?

    <p>Polycythemia vera</p> Signup and view all the answers

    What is the purpose of contrast venography in the context of VTE diagnosis?

    <p>To visualize the entire venous system in the lower extremity and abdomen</p> Signup and view all the answers

    In the Modified Wells Criteria, what score indicates a high probability of having acute DVT?

    <p>Score &gt; 3</p> Signup and view all the answers

    What is the primary purpose of pulmonary angiography in the context of VTE diagnosis?

    <p>To visualize the pulmonary arteries</p> Signup and view all the answers

    What is the main function of ultrasonography in the diagnosis of VTE?

    <p>To detect acute thrombosis</p> Signup and view all the answers

    What is the main purpose of ventilation-perfusion scans in the diagnosis of VTE?

    <p>To assess lung function</p> Signup and view all the answers

    What is the primary manifestation of DVT in terms of patient presentation?

    <p>Unilateral leg pain, swelling persisting after a night’s sleep</p> Signup and view all the answers

    What is the primary risk factor for VTE associated with vascular injury?

    <p>Trauma and indwelling venous catheters</p> Signup and view all the answers

    What is the main function of the Modified Caprini Risk Assessment Model for VTE?

    <p>To assess the risk of VTE in surgical patients</p> Signup and view all the answers

    Which condition is associated with venous stasis?

    <p>Obesity</p> Signup and view all the answers

    What is a long-term complication of deep vein thrombosis (DVT)?

    <p>Chronic lower extremity swelling</p> Signup and view all the answers

    What is a risk factor for venous thromboembolism (VTE)?

    <p>Anti-phospholipid antibodies</p> Signup and view all the answers

    What is a symptom frequently associated with deep vein thrombosis (DVT)?

    <p>Swelling persist after a night’s sleep</p> Signup and view all the answers

    Which test is used frequently for the initial evaluation of patients with suspected VTE?

    <p>D-dimer</p> Signup and view all the answers

    What is the normal range for D-dimer?

    <p>Less than 0.5 mg/L</p> Signup and view all the answers

    What is a characteristic of the intrinsic coagulation pathway?

    <p>Conversion of prothrombin to thrombin</p> Signup and view all the answers

    What is a characteristic of the extrinsic coagulation pathway?

    <p>Exposure of collagen to Factor XII &amp; thrombocytes</p> Signup and view all the answers

    What is the triggering step for the intrinsic coagulation pathway?

    <p>Slow to proceed</p> Signup and view all the answers

    What is the triggering step for the extrinsic coagulation pathway?

    <p>Exposure of collagen to Factor XII &amp; thrombocytes</p> Signup and view all the answers

    What is the monitoring test for the intrinsic coagulation pathway?

    <p>Less = bleeding More = clotting</p> Signup and view all the answers

    What is the monitoring test for the extrinsic coagulation pathway?

    <p>PT (10-30 sec)</p> Signup and view all the answers

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