Resp Pharm Part 1
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Questions and Answers

Which generation of antihistamines includes cetirizine and fexofenadine?

  • Fourth generation
  • First generation
  • Second generation (correct)
  • Third generation
  • What is the mechanism of action of peripheral acting antitussives?

  • Acting directly on cough receptors in the trachea, pharynx, and lungs (correct)
  • Reducing mucous viscosity for easier sputum expulsion
  • Causing irritation leading to increased bronchial secretions
  • Suppressing the cough reflex center in the brain
  • Which antitussive should be avoided in patients with COPD and asthma?

  • Hydrocodone
  • Benzonatate (correct)
  • Codeine
  • Dextromethorphan
  • What is a common side effect of mucolytics?

    <p>Bronchospasm</p> Signup and view all the answers

    Which action do expectorants have to help with sputum expulsion?

    <p>Causing irritation to increase bronchial secretions</p> Signup and view all the answers

    What is the main nursing implication for antitussives?

    <p>Recommend limiting use to 4 days</p> Signup and view all the answers

    Which symptom is a side effect of first-generation antihistamines?

    <p>Paradoxical excitement</p> Signup and view all the answers

    Which medication is used as an antidote for Acetaminophen poisoning and also as a mucolytic?

    <p>Acetylcysteine</p> Signup and view all the answers

    What is the primary nursing implication for expectorants?

    <p>Encourage increased fluid intake and humidification</p> Signup and view all the answers

    Which group of antihistamines can cause systemic effects like CNS and cardiac stimulation?

    <p>First Generation Antihistamines</p> Signup and view all the answers

    Which statement regarding the administration of antihistamines is correct?

    <p>Diphenhydramine should be given parenterally via deep intramuscular injection.</p> Signup and view all the answers

    Which of the following statements about nasal decongestants is incorrect?

    <p>Triamcinolone is a sympathomimetic nasal decongestant.</p> Signup and view all the answers

    Which of the following statements about central acting antitussives is correct?

    <p>They can cause respiratory depression and constipation as side effects.</p> Signup and view all the answers

    Which of the following statements about indirect acting expectorants is incorrect?

    <p>They act directly on bronchial glands to reduce mucous viscosity.</p> Signup and view all the answers

    Which of the following nursing implications is incorrect for mucolytics?

    <p>Store mucolytic solutions at room temperature and discard after 96 hours.</p> Signup and view all the answers

    Which of the following statements about antihistamines is true?

    <p>First-generation antihistamines are less likely to cause drowsiness compared to second-generation antihistamines.</p> Signup and view all the answers

    Which of the following statements regarding nasal decongestants is correct?

    <p>Assessing nasal mucosa is an important nursing implication when using nasal decongestants.</p> Signup and view all the answers

    Which of the following statements about peripheral acting antitussives is incorrect?

    <p>They suppress the cough reflex center in the brain.</p> Signup and view all the answers

    Which of the following statements about expectorants is true?

    <p>Direct acting expectorants act directly on bronchial glands to increase mucous production.</p> Signup and view all the answers

    Which of the following statements about mucolytics is incorrect?

    <p>Mucolytic solutions should be stored at room temperature and discarded after 48 hours.</p> Signup and view all the answers

    Which side effect is common with the use of first-generation antihistamines?

    <p>Drowsiness</p> Signup and view all the answers

    What is the primary action of sympathomimetics in nasal decongestants?

    <p>Constrict blood vessels in the nose</p> Signup and view all the answers

    Which drug is an example of a central acting antitussive?

    <p>Codeine</p> Signup and view all the answers

    In what way do indirect acting expectorants work?

    <p>By causing irritation to increase bronchial secretions</p> Signup and view all the answers

    Which side effect is associated with central acting antitussives?

    <p>Drowsiness</p> Signup and view all the answers

    What is a common adverse effect of expectorants?

    <p>Drowsiness</p> Signup and view all the answers

    How do first-generation antihistamines exert their effects?

    <p>By blocking histamine at H1 receptors</p> Signup and view all the answers

    'Which symptom should the nurse monitor for when administering central acting antitussives?

    <p>Euphoria and constipation</p> Signup and view all the answers

    Which correct option is associated with sympathomimetics?

    <p>Constrict blood vessels in the nose</p> Signup and view all the answers

    Which option is true regarding diphenhydramine and hydroxyzine?

    <p>They are first-generation antihistamines.</p> Signup and view all the answers

    Which of the following is the primary mechanism of action for second-generation antihistamines?

    <p>Preventing histamine from entering the receptor site</p> Signup and view all the answers

    What is the primary nursing implication when administering peripheral acting antitussives like benzonatate?

    <p>Ensure the capsules are swallowed whole</p> Signup and view all the answers

    How do direct acting expectorants help with sputum expulsion?

    <p>By reducing the viscosity of mucus</p> Signup and view all the answers

    Which of the following is a common adverse effect associated with the use of mucolytics?

    <p>Hypersensitivity reactions</p> Signup and view all the answers

    Which type of nasal decongestant works by decreasing mucous formation and reducing swelling?

    <p>Corticosteroids</p> Signup and view all the answers

    Which of the following is a common side effect associated with the use of first-generation antihistamines?

    <p>Drowsiness</p> Signup and view all the answers

    What is the primary action of sympathomimetics in nasal decongestants?

    <p>Constricting blood vessels in the nose</p> Signup and view all the answers

    Which of the following is an example of a central acting antitussive?

    <p>Dextromethorphan</p> Signup and view all the answers

    Which medication is used as both an antidote for acetaminophen poisoning and as a mucolytic?

    <p>Acetylcysteine</p> Signup and view all the answers

    Which of the following statements about indirect acting expectorants is incorrect?

    <p>They act directly on bronchial glands to increase secretions</p> Signup and view all the answers

    Which adverse effect is commonly associated with first-generation antihistamines?

    <p>Sedation</p> Signup and view all the answers

    What is the primary nursing implication for administering expectorants?

    <p>Position the patient in high fowlers</p> Signup and view all the answers

    Which drug is an example of a central acting antitussive?

    <p>Dextromethorphan</p> Signup and view all the answers

    What is the primary mechanism of action for second-generation antihistamines?

    <p>Blocking histamine at H1 receptors</p> Signup and view all the answers

    Which symptom is a common side effect of mucolytics?

    <p>Nausea and vomiting</p> Signup and view all the answers

    What is the primary nursing implication when administering peripheral acting antitussives like benzonatate?

    <p>Ensure capsules are swallowed whole</p> Signup and view all the answers

    'What symptom should the nurse monitor for when administering central acting antitussives?

    <p>Respiratory depression</p> Signup and view all the answers

    What is the primary concern when administering central acting antitussives to patients with increased intracranial pressure?

    <p>Worsening of intracranial pressure</p> Signup and view all the answers

    Which of the following statements regarding the administration of mucolytics is correct?

    <p>Liquid forms of mucolytics can be mixed with cola or fruit juice</p> Signup and view all the answers

    Which of the following statements regarding indirect acting expectorants is true?

    <p>They cause irritation leading to increased bronchial secretions</p> Signup and view all the answers

    Which of the following adverse effects is most commonly associated with the use of first-generation antihistamines?

    <p>Sedation and drowsiness</p> Signup and view all the answers

    Which of the following statements regarding nasal decongestants is correct?

    <p>Rebound congestion can occur with prolonged use beyond 4 days</p> Signup and view all the answers

    Which of the following nursing implications is most important when administering peripheral acting antitussives like benzonatate?

    <p>Ensure capsules are swallowed whole</p> Signup and view all the answers

    Which of the following statements regarding the mechanism of action of second-generation antihistamines is correct?

    <p>They block histamine at H1 receptors, preventing histamine from entering the receptor site</p> Signup and view all the answers

    Which of the following statements regarding the administration of expectorants is correct?

    <p>Deep breathing and coughing exercises should be encouraged</p> Signup and view all the answers

    Which of the following statements regarding the use of mucolytics is incorrect?

    <p>Liquid forms of mucolytics should be mixed with water</p> Signup and view all the answers

    Which of the following statements regarding the mechanism of action of direct acting expectorants is correct?

    <p>They act directly on bronchial glands</p> Signup and view all the answers

    What is the primary mechanism of action for second-generation antihistamines?

    <p>They block histamine at H1 receptors, preventing histamine from entering the receptor site.</p> Signup and view all the answers

    Which type of nasal decongestant works by decreasing mucous formation and reducing swelling?

    <p>Corticosteroids</p> Signup and view all the answers

    What is the primary nursing implication when administering peripheral acting antitussives like benzonatate?

    <p>Ensure benzonatate capsules are swallowed whole</p> Signup and view all the answers

    Which medication is used as both an antidote for acetaminophen poisoning and as a mucolytic?

    <p>Acetylcysteine (Cetylev)</p> Signup and view all the answers

    Which of the following statements regarding the mechanism of action of direct acting expectorants is correct?

    <p>They act directly on bronchial glands to increase secretions.</p> Signup and view all the answers

    Study Notes

    • Antihistamines work by blocking histamine at H1 receptors to prevent its action, used for hypersensitivity reactions, seasonal allergies, nausea, vomiting, and motion sickness.
    • First-generation antihistamines include diphenhydramine, hydroxyzine, and promethazine, while second-generation ones include cetirizine, loratadine, fexofenadine, and desloratadine.
    • Side effects of antihistamines may include drying effect, drowsiness, hypotension, gastrointestinal irritation, photosensitivity reactions, and paradoxical excitement.
    • Nursing implications for antihistamines involve taking with food (except loratadine), avoiding fruit juice with fexofenadine, administering parenterally in a deep IM injection, and monitoring drowsiness levels.
    • Nasal decongestants are used to drain sinus cavities, with corticosteroids decreasing mucous formation and sympathomimetics constricting blood vessels in the nose.
    • Side effects of nasal decongestants can be systemic (CNS and cardiac stimulation) and local (rebound congestion), requiring assessment of nasal mucosa and monitoring blood pressure and heart rate.
    • Antitussives can be central acting (suppressing cough reflex center) or peripheral acting (acting directly on cough receptors), with examples like codeine, hydrocodone, dextromethorphan, and benzonatate.
    • Nursing implications for antitussives involve avoiding in conditions like COPD and asthma, ensuring benzonatate capsules are swallowed whole, and informing the physician if cough persists beyond 5-7 days.

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