Histamine and Antihistamines Quiz
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Questions and Answers

What is the primary mechanism of action of antihistamine drugs?

  • Binding to histamine receptors on nerve endings
  • Preventing the synthesis of histamine molecules
  • Competing with histamine for unoccupied receptors on basophils and mast cells (correct)
  • Pushing off histamine already bound to a receptor

When are antihistamines most beneficial in a histamine-mediated reaction?

  • After all free histamine molecules bind to cell membrane receptors
  • When all histamine molecules are already bound to receptors
  • During the release of histamine from basophils and mast cells
  • Before all free histamine molecules bind to cell membrane receptors (correct)

Which of the following is NOT a consequence of histamine binding that is prevented by H1 blockers?

  • Decreased capillary permeability (correct)
  • Vasodilation
  • Increased GI secretions
  • Increased salivary secretions

What are antihistamines indicated for the treatment of?

<p>Seasonal allergic rhinitis (B)</p> Signup and view all the answers

What is a contraindication for the use of antihistamines?

<p>Known drug allergy (B)</p> Signup and view all the answers

How do antihistamines affect the release and actions of histamine stored within basophils and mast cells?

<p>Prevent the release and actions of stored histamine (A)</p> Signup and view all the answers

What are the common adverse effects of benzonatate?

<p>Dizziness, headache, and sedation (C)</p> Signup and view all the answers

Which antitussive drug is classified as a pregnancy category C drug?

<p>Benzonatate (C)</p> Signup and view all the answers

What are the common adverse effects of codeine and hydrocodone?

<p>Sedation, nausea, and vomiting (B)</p> Signup and view all the answers

How does benzonatate work as an antitussive drug?

<p>By numbing or anesthetizing the cough receptors (B)</p> Signup and view all the answers

Which antitussive is commonly available over-the-counter (OTC)?

<p>Dextromethorphan (D)</p> Signup and view all the answers

What is a potential drug interaction associated with opioid antitussives like codeine and hydrocodone?

<p>Potentiation with other opioids and CNS depressants (C)</p> Signup and view all the answers

How do nasal decongestants primarily work?

<p>By constricting the small arterioles in the nasal mucous membranes (D)</p> Signup and view all the answers

Which of the following is not a commonly used intranasal steroid?

<p>Mometasone furoate (Nasonex) (C)</p> Signup and view all the answers

Which of the following drugs is an intranasal anticholinergic?

<p>Ipratropium (A)</p> Signup and view all the answers

What is the primary purpose of using intranasal steroids?

<p>To prevent nasal congestion (A)</p> Signup and view all the answers

Why are nasal decongestants referred to as sympathomimetics?

<p>Because they produce effects similar to sympathetic nervous system stimulation (D)</p> Signup and view all the answers

What is the mechanism of action of adrenergic drugs like ephedrine and oxymetazoline?

<p>By constricting small arterioles supplying nasal structures (B)</p> Signup and view all the answers

Which of the following statements about codeine-containing cough suppressants is true?

<p>They can cause respiratory depression as part of their effects. (D)</p> Signup and view all the answers

What is the pregnancy category classification of codeine?

<p>Category C (C)</p> Signup and view all the answers

What characteristic makes dextromethorphan different from codeine when used in recommended dosages?

<p>It is safe. (A)</p> Signup and view all the answers

In what dosage forms is dextromethorphan available?

<p>Lozenges, liquid-filled capsules, tablets, and suspension (A)</p> Signup and view all the answers

What patient condition is a contraindication for using dextromethorphan?

<p>Asthma or emphysema (B)</p> Signup and view all the answers

What is the most significant difference between codeine and dextromethorphan in terms of potential abuse?

<p>Codeine has become a popular drug of abuse while dextromethorphan has not. (C)</p> Signup and view all the answers

What is a contraindication for inhaled intranasal steroids?

<p>Nasal mucosal infection (A)</p> Signup and view all the answers

What is an important aspect to include in the assessment when using decongestants?

<p>Assessment of signs and symptoms before and after use (D)</p> Signup and view all the answers

What is a common side effect associated with antitussive therapy?

<p>Sedation, dizziness, and drowsiness (D)</p> Signup and view all the answers

What additional aspect might the prescriber order for individuals with chronic respiratory disease before prescribing certain drugs?

<p>Further studies to determine safety (B)</p> Signup and view all the answers

What is used to provide more information during the assessment in addition to respiratory parameters?

<p>Pulse oximetry readings with vital signs (B)</p> Signup and view all the answers

Which of the following is a potential drug interaction to assess for when administering certain medications?

<p>Alcohol (C)</p> Signup and view all the answers

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