Podcast
Questions and Answers
What is the primary goal of treatment in epilepsy?
What is the primary goal of treatment in epilepsy?
- Enhancing fast GABA mediated synaptic inhibition
- Preventing the occurrence of seizures (correct)
- Correcting the underlying cause of the disorder
- Modifying the electrical properties of affected cells
What is the mechanism of action of Phenytoin?
What is the mechanism of action of Phenytoin?
- Inhibiting voltage-gated calcium channels
- Use-dependent block of sodium channels (correct)
- Modifying synaptic release processes
- Enhancing fast GABA mediated synaptic inhibition
What is the primary indication for Gabapentin in epilepsy treatment?
What is the primary indication for Gabapentin in epilepsy treatment?
- Myoclonic seizures
- Absence seizures
- Tonic-clonic seizures
- Focal seizures (correct)
What is the auxiliary subunit of voltage-gated P/Q type calcium channels that Gabapentin binds to?
What is the auxiliary subunit of voltage-gated P/Q type calcium channels that Gabapentin binds to?
What is a common side effect of long-term Phenytoin use?
What is a common side effect of long-term Phenytoin use?
What is the term used to describe patients who do not achieve control with two or more antiepileptic drugs?
What is the term used to describe patients who do not achieve control with two or more antiepileptic drugs?
What percentage of patients with epilepsy have their seizures completely controlled with optimal drug therapy?
What percentage of patients with epilepsy have their seizures completely controlled with optimal drug therapy?
What is the approximate percentage of the population affected by epilepsy?
What is the approximate percentage of the population affected by epilepsy?
What is the primary cause of seizures in epilepsy?
What is the primary cause of seizures in epilepsy?
What is the approximate percentage of epilepsy cases that are familial and involve genetic mutations?
What is the approximate percentage of epilepsy cases that are familial and involve genetic mutations?
What is the typical duration of antiepileptic drug therapy for patients with epilepsy?
What is the typical duration of antiepileptic drug therapy for patients with epilepsy?
What is the primary goal of treatment in Parkinson's disease?
What is the primary goal of treatment in Parkinson's disease?
What is the typical duration of therapy for epilepsy?
What is the typical duration of therapy for epilepsy?
What is the male to female ratio of Parkinson's disease incidence?
What is the male to female ratio of Parkinson's disease incidence?
What is the percentage of striatal dopamine that must be lost before symptoms of Parkinson's disease appear?
What is the percentage of striatal dopamine that must be lost before symptoms of Parkinson's disease appear?
What is the effect of dopamine on cholinergic neurons in the normal brain?
What is the effect of dopamine on cholinergic neurons in the normal brain?
What is the first line treatment for Parkinson's disease?
What is the first line treatment for Parkinson's disease?
What is the percentage of patients who show marked initial improvement with levodopa therapy?
What is the percentage of patients who show marked initial improvement with levodopa therapy?
What is the major limitation of levodopa therapy?
What is the major limitation of levodopa therapy?
What is the mechanism of action of trihexyphenidyl?
What is the mechanism of action of trihexyphenidyl?
What is the 'on-off' effect seen in patients on long-term levodopa therapy?
What is the 'on-off' effect seen in patients on long-term levodopa therapy?
