Pharmaceutical Chemistry - Antiepileptics

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Questions and Answers

Which of the following is NOT classified as a hydantoin derivative?

  • Methoin
  • Primidone (correct)
  • Ethoin
  • Phenytoin

Which of the following is an example of a benzodiazepine used as an antiepileptic?

  • Diazepam (correct)
  • Carbamazepine
  • Phenobarbitone
  • Sodium valproate

Which classification includes ethosuximide?

  • Hydantoin derivative
  • Succinimides (correct)
  • Benzodiazepine
  • Carboxylic acid derivative

What type of drug is phenytoin?

<p>Hydantoin (B)</p> Signup and view all the answers

Which of the following pairs a class of antiepileptic with the correct example drug?

<p>Iminostilbene - Carbamazepine (C)</p> Signup and view all the answers

Flashcards

Antiepileptic/Anticonvulsant Definition

Drugs used to treat epilepsy

Hydantoin Derivative Example

A type of anticonvulsant including drugs like phenytoin, ethoin, and methoin.

Hydantoin Chemical Structure

Imidazolidine 2,4-dione.

Phenytoin (drug class)

A hydantoin derivative used to treat epilepsy.

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Antiepileptic Drug Classification

Different groups of drugs (e.g., hydantoins, barbiturates, benzodiazepines) categorized by chemical structure or mechanism of action.

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Study Notes

Pharmaceutical Chemistry - Antiepileptics

  • Antiepileptics/Anticonvulsants are drugs used to treat various types of epilepsy.
  • Classification of Antiepileptics:
    • Hydantoin derivatives: Examples include phenytoin, etho-in, methoin.
    • Barbiturates: Examples include phenobarbital, mephobarbital.
    • Benzodiazepines: Examples include diazepam, nitrazepam.
    • Iminostilbene/Dibenzazepine derivatives: Example is carbamazepine.
    • Carboxylic acid derivatives: Example is sodium valproate.
    • Succinimides: Examples include ethosuximide, phensuximide.
    • Oxazolidinedione derivatives: Example is paramethadione.
    • Deoxy barbiturates: Example is primidone.
    • Phenyltriazines: Example is lamotrigine.
    • Cyclic GABA analogues: Example is gabapentin.
    • Newer drugs: Vigabatrin, topiramate, zonisamide, tiagabine.

Hydantoin Definition and Examples

  • Hydantoin is a chemical structure with the formula imidazolidine 2,4-dione.
  • Examples of hydantoin drugs include phenytoin, etho-in, methoin.
  • Phenytoin is a hydantoin derivative (imidazolidine 2,4-dione derivative).

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