24 Questions
Which of the following antibiotics is most effective in treating Gram+ infections?
Penicillins
What is the most serious complication of using Penicillins?
Hypersensitivity and nephropathy
Which of the following antibiotics is derived from a fungus?
Penicillins and Cephalosporins
What is the main reason for using combinations of antibiotics with beta-lactamase inhibitors?
To prevent the inactivation of antibiotics by beta-lactamase
Which of the following antibiotics has poor distribution to the CNS?
All of the above
Which of the following antibiotics is used to treat infections of the skin, GU, GI, respiratory tract, and soft tissues?
Penicillins
Why should Aminoglycosides be used cautiously in patients with Myasthenia Gravis or neuromuscular disorders?
Because they can increase muscle weakness
What is the main reason for the poor absorption of Aminoglycosides from the GI tract?
They are not absorbed from the GI tract due to their charge and size
Which of the following antibiotics is NOT used in surgical prophylaxis?
Beta-lactamase inhibitors
What is the mechanism of action of antibiotics used in the long-term treatment of acne?
Interference with production of free fatty acids
Which antibiotic is effective against gram-positive and gram-negative bacteria?
Chloramphenicol
What is the main indication for the use of Metronidazole?
Treatment of intestinal protozoal infections
Which antibiotic is commonly used to treat MRSA infections?
Vancomycin
What is the potential adverse effect of rapid infusion of Vancomycin?
Flushing and skin rash
Which antibiotic is similar in action to macrolides?
Clindamycin
What is the indication for the use of Clindamycin?
Treatment of acne
What type of bacteria is Metronidazole effective against?
Anaerobic bacteria
What is the mechanism of action of fluoroquinolones?
Interfering with DNA gyrase
What is a contraindication for the use of fluoroquinolones?
Pregnant or lactating women
What is a common side effect of sulfonamides?
All of the above
What is the indication for clarithromycin in the treatment of H. pylori?
Helicobacter pylori infection
What is the primary mechanism of action of macrolides?
Inhibiting bacterial protein synthesis
What is a common interaction with macrolides?
Food can interfere with absorption
What is the primary indication for the combination of trimethoprim and sulfamethoxazole?
Urinary tract infections
This quiz covers the properties and uses of penicillins, including their administration, distribution, and effectiveness in treating various infections. It also explores the complications and side effects of penicillin use. Test your knowledge of these antibiotics and their derivatives!
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