22 Questions
What is the mechanism of action of Caspofungin, Micafungin, and Anidulafungin?
Inhibition of B-(1,3)-D-glucan synthase
What is the primary mechanism of cell death caused by Caspofungin, Micafungin, and Anidulafungin?
Disruption of glucan synthesis leading to cell rupture
Which of the following fungi is NOT affected by Caspofungin, Micafungin, and Anidulafungin?
Cryptococcus neoformans
What is the mechanism of action of cycloserine against Mycobacterium tuberculosis?
Competitive inhibition of D-alanine involved in bacterial cell wall synthesis
What is the primary mechanism of action of Amphotericin B?
Binding to ergosterol in the cell membrane
Which of the following antitubercular drugs is no longer available?
Viomycin
What is the primary use of Nystatin?
Treatment of oral candidiasis
What is the main disadvantage of using Amikacin and Kanamicin in the treatment of MDR tuberculosis?
High cost
What is the primary use of Natamycin?
Treatment of fungal keratitis and blepharitis
What is the mechanism of action of fluoroquinolones against Mycobacterium tuberculosis?
Inhibition of bacterial DNA gyrase
Which of the following antitubercular drugs is contraindicated in patients with underlying psychiatric and seizure disorders?
Cycloserine
What is the primary activity of Clofazimine against Mycobacterium?
M. leprae
What is the primary mechanism of action of Rifampicin in treating tuberculosis?
Binding to the subunit of bacterial DNA-dependent RNA polymerase
What is the main component of the Mycobacterium tuberculosis cell wall?
Mycolic acid
Which of the following antitubercular drugs is a synthetic analogue of nicotinamide?
Pyrazinamide
What is the term for the staining technique used to visualize Mycobacterium tuberculosis?
Acid-Fast Staining
Which of the following antitubercular drugs is not recommended for use alone due to the risk of resistance?
Ethambutol
What is the main reason for the resistance of Mycobacterium tuberculosis to many antibiotics?
High concentration of lipids in the cell wall
Which of the following antitubercular drugs is known for its hepatotoxic effects?
Pyrazinamide
What is the mechanism of action of Pyrazinamide in treating tuberculosis?
Inhibiting the incorporation of mycolic acid in the cell wall
Which of the following antitubercular drugs is known for its vestibulotoxic effects?
Streptomycin
What is the term for the disease caused by Mycobacterium tuberculosis?
Koch Disease
Test your knowledge of antibiotics and urinary antiseptics, including quinolones, nitrofurans, and their interactions with other medications. Learn about their mechanisms of action and potential side effects.
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