Antibiotic Resistance and Traditional Medicinal Plants

Antibiotic Resistance Crisis

• Two million people in the US acquire antibiotic-resistant infections each year, with the number continuing to rise.
• The dwindling efficacy of pharmaceutical antibiotics has led to a renewed interest in traditional medicinal plants for supporting the body's antimicrobial defenses.

Botanicals with Antimicrobial Activity

• Artemisia annua has potent antimalarial activity and is also effective against various pathogens, including periodontal microbes and Staphylococcus aureus.
• Berberine, found in Berberis species, has potent antimicrobial activity against pathogenic microbes.
• Cinnamon essential oil has antimicrobial activity against Borrelia burgdorferi, H.pylori, Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, and Candida albicans.
• CBD, a phytocannabinoid, is a potent antimicrobial, inhibiting the growth of Staphylococcus aureus and Streptococcus pneumoniae with a potency similar to vancomycin and daptomycin.

Botanicals Modulating Cytokine Response

• Curcuminoids, including curcumin and turmeric essential oils, possess antimicrobial and anti-inflammatory effects.
• Curcumin inhibits the growth of Staphylococcus aureus, E.coli, Salmonella, and Candida, while decreasing pro-inflammatory cytokines.
• Boswellia has antimicrobial activities against Staphylococcus aureus, Streptococcus pneumoniae, E.coli, Klebsiella pneumonia, Pseudomonas aeruginosa, and Proteus vulgaris.
• A combination of curcumin and Boswellia extract is more potent than either compound alone for supporting a healthy cytokine response.

Liver and Mast Cell Support

• Milk thistle is profoundly hepatoprotective, supporting liver function and balancing the immune system and systemic inflammatory responses.
• Quercetin, found in edible plants, helps stabilize mast cells, modulating the body's inflammatory response to immune stressors.

Building a Resilient Internal Terrain

• Andrographis and propolis are rich sources of immunomodulatory compounds that support a healthy internal terrain.
• Andrographolide has potent immune-stimulating, anti-microbial, anti-inflammatory properties.
• Propolis has immunomodulatory, antibacterial, antiviral, and antifungal effects.

SEDS Delivery Technology

• Self-emulsifying delivery systems (SEDS) represent a new frontier in nutraceutical delivery systems.