Anti-Histamine Medication Study Notes
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Questions and Answers

What type of medication is Diphenhydramine (Benadryl) classified as?

  • Anticholinergic medication
  • H2 blocker
  • MAOI antidepressant
  • H1 blocker (correct)
  • What is the primary mechanism of action of anti-histamines in treating allergic reactions?

  • Increasing serotonin levels
  • Blocking histamine receptors (correct)
  • Reducing histamine release from mast cells
  • Reducing dopamine levels
  • What is a common side effect of anti-histamines?

  • Headache (correct)
  • Seizures
  • Confusion
  • All of the above
  • What is a potential interaction of anti-histamines with sedatives and tranquilizers?

    <p>Increased risk of drowsiness</p> Signup and view all the answers

    Which of the following anti-histamines is considered non-drowsy?

    <p>Loratadine (Claritin)</p> Signup and view all the answers

    What is a less common side effect of anti-histamines?

    <p>Hallucinations</p> Signup and view all the answers

    What is the primary function of H1 histamine receptors?

    <p>Allergic responses, smooth muscle contraction, and increased vascular permeability</p> Signup and view all the answers

    What is the effect of histamine release on blood vessels during an allergic reaction?

    <p>Vasodilation and increased blood flow</p> Signup and view all the answers

    What is the underlying cause of histamine intolerance?

    <p>Deficient diamine oxidase (DAO) enzyme or gastrointestinal disorders</p> Signup and view all the answers

    What is the role of histamine in the regulation of gastric acid secretion?

    <p>Stimulating gastric acid secretion and increasing gut motility</p> Signup and view all the answers

    What is the role of histamine in the brain?

    <p>Arousal and wakefulness, appetite regulation, sleep-wake cycle, and pain modulation</p> Signup and view all the answers

    What is a potential consequence of imbalances in histamine levels or receptor function in the brain?

    <p>Increased risk of neurological disorders, such as ADHD, anxiety, and depression</p> Signup and view all the answers

    Study Notes

    Anti-Histamine Study Notes

    Medication Interactions

    • Anti-histamines can interact with:
      • Sedatives and tranquilizers, increasing the risk of drowsiness
      • Anticholinergic medications, increasing the risk of dry mouth, constipation, and urinary retention
      • MAOI (monoamine oxidase inhibitors) antidepressants, increasing the risk of serotonin syndrome

    Histamine Blockers

    • Anti-histamines work by blocking histamine receptors (H1, H2, H3, H4) in the body
    • H1 blockers:
      • Diphenhydramine (Benadryl)
      • Loratadine (Claritin)
      • Cetirizine (Zyrtec)
    • H2 blockers:
      • Ranitidine (Zantac)
      • Famotidine (Pepcid)

    Allergic Reactions

    • Anti-histamines are used to treat allergic reactions by:
      • Reducing histamine release from mast cells
      • Blocking histamine receptors, reducing symptoms such as itching, sneezing, and runny nose

    Side Effects

    • Common side effects of anti-histamines:
      • Drowsiness
      • Dizziness
      • Dry mouth
      • Headache
      • Stomach upset
    • Less common side effects:
      • Confusion
      • Hallucinations
      • Seizures

    Non-Drowsy Options

    • Non-drowsy anti-histamines:
      • Loratadine (Claritin)
      • Cetirizine (Zyrtec)
      • Fexofenadine (Allegra)
      • Levocetirizine (Xyzal)
    • These medications are designed to reduce the risk of drowsiness, but may still cause drowsiness in some individuals.

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    Description

    Learn about anti-histamine medications, their interactions, effects, and side effects. Understand how they work, their types, and non-drowsy options. A study guide for medical students and professionals.

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